Proteomic study of a Parkinson’s disease model of undifferentiated SH-SY5Y cells induced by a proteasome inhibitor

Parkinson's disease (PD) is one of the most common nervous system degenerative diseases. However, the etiology of this disease remains elusive. Here, a proteasome inhibitor (PSI)-induced undifferentiated SH-SY5Y PD model was established to analyze protein alterations through proteomic study.