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Regulation of calretinin in malignant mesothelioma is mediated by septin 7 binding to the CALB2 promoter
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The calcium-binding protein calretinin (gene name: CALB2) is currently considered as the most sensitive and specific marker for the diagnosis of malignant mesothelioma (MM). MM is a very aggressive tumor strongly linked to asbestos exposure and with no existing cure so far.
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