Response surface methodology optimization of polyhydroxyalkanoate by recombinant Bacillus megaterium pPSPHAR1/1 strain using fish processing waste production

Polyhydroxyalkanoates (PHAs) are biomaterials that are accumulated intracellularly by bacterial cells in response to nutrient imbalances under environmental stress. Polyhydroxybutyrate (PHB) is a bioplastic that is of interest to research to find an alternative to fossil-derived plastics.