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Single molecule sequencing-guided scaffolding and correction of draft assemblies

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Although single molecule sequencing is still improving, the lengths of the generated sequences are inevitably an advantage in genome assembly. Prior work that utilizes long reads to conduct genome assembly has mostly focused on correcting sequencing errors and improving contiguity of de novo assemblies.

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Nội dung Text: Single molecule sequencing-guided scaffolding and correction of draft assemblies

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