The combination of methotrexate and cytosine arabinoside in newly diagnosed adult Langerhans cell histiocytosis: A prospective phase II interventional clinical trial

Langerhans Cell Histiocytosis (LCH) is a rare disease puzzling both children and adults, however outcome of adult patients is unfavorable. This prospective interventional trial aims to test the efficacy and safety of the combination of methotrexate and cytosine arabinoside in adult LCH patients.