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The dog as a naturally-occurring model for insulin-like growth factor type 1 receptoroverexpressing breast cancer: An observational cohort study
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Dogs spontaneously develop invasive mammary carcinoma with a high prevalence of the triple-negative (TN) subtype (lack of ER-Estrogen Receptor and PR-Progesterone Receptor expression, lack of HER2-Human Epidermal Growth Factor Receptor 2 overexpression), making this animal model relevant for investigating new therapeutic pathways.
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