The impairment of osteogenic differentiation of human adipose tissue-derived mesenchymal stem cells under high D-glucose concentrations

Type 2 diabetic patients have an increased risk of developing serious long-term complications such as cardiovascular disease, retinopathy, nephropathy, neuropathy, diabetic foot, and osteoporosis. However, the correlation between hyperglycaemia and osteoporosis has not yet been fully clarified.