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A clinical approach
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cancer (GC) lacks serum biomarkers with clinical diagnostic value. Multi-omics analysis is an important approach to discovering cancer biomarkers. This study aimed to identify and validate serum biomarkers for GC diagnosis by cross-analysis of proteomics and transcriptomics datasets.
13p
vishanshan
27-06-2024
2
1
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There is an aberrant expression of NBAT-1 in various human cancers, which was proven to limit the proliferation, invasion, and metastasis of tumour cells via multiple approaches. Most existing research focuses on sample size and discrete outcomes. Thus, a quantitative meta-analysis was performed to elucidate the prognostic value of lncRNA NBAT-1 expression in cancer patients.
12p
vishanshan
27-06-2024
2
1
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Patient-centred measurement (PCM) emphasizes a holistic approach wherein the voices of patients are reflected in the standardized use of patient-reported outcome and experience measures and are represented throughout the continuum of measurement activities. Given the challenges of routinely integrating patient self reports into clinical care decisions, the perspectives of all healthcare system stakeholders, especially patients, is necessary to advance the science of PCM.
13p
vishanshan
27-06-2024
1
1
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This paper responds to the recently published article by Wang et al. and will expand the discourse regarding management of localized MCC. Specifically, we will discuss the surgical excision approaches; alternative treatment options for MCC including radiotherapy, Mohs micrographic surgery and novel immunotherapy agents being investigated through several clinical trials.
3p
vikoch
27-06-2024
2
1
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The efficacy and safety of subxiphoid thoracoscopic thymectomy (SVATS) for early thymoma are unknown. The purposes of this meta-analysis were to evaluate the effectiveness and safety of SVATS for early thymoma, to compare it with unilateral intercostal approach video thoracoscopic surgery (IVATS) thymectomy, and to investigate the clinical efficacy of modified subxiphoid thoracoscopic thymectomy (MSVATS) for early anterior mediastinal thymoma.
13p
vikoch
27-06-2024
3
1
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Evidence suggests a direct correlation between the quality of postoperative orthopaedic rehabilitation and the effectiveness of the surgery. Clinical orthopaedic rehabilitation: A team approach helps today’s orthopaedic teams apply the most effective, evidence-based protocols for maximizing return to function following common sports injuries and post-surgical conditions.
732p
vimeyers
29-05-2024
6
2
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Ebook "Lymphangiogenesis in cancer metastasis" covers all aspects of this new field from the fundamental role that protein growth factors and their receptors play in lymphangiogenesis to the potential application of these advances to cancer diagnosis and treatment. Other clinical aspects explored include the mechanisms and importance of lymph node metastasis, the role of the lymphatics in lymphangioleiomyomatosis and Kaposi’s sarcoma, and approaches for imaging lymphatics in cancer.
254p
dongmelo
27-05-2024
6
2
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In this study, two derivatives of hydrazineylidene-3-oxopropanal: chlorophenyl (CPHO) and Nitrophenyl (NPHO) substituted hydrazineylidene compounds were synthesized, spectroscopically characterized using (FT-IR, UV, and NMR), and theoretically modelled as a potential drug for the treatment of antiviral hepatitis (HBV and HCV) using insillico molecular docking approach.
17p
dianmotminh02
03-05-2024
3
1
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Part 1 book "Kanski’s clinical ophthalmology - A systematic approach" includes content: Examination techniques, eyelids, lacrimal drainage system, dry eye, conjunctiva, cornea, orbit, corneal and refractive surgery.
297p
zizaybay1101
30-04-2024
3
2
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Part 2 book "Kanski’s clinical ophthalmology - A systematic approach" includes content: Episclera and sclera, lens, retinal vascular disease, glaucoma, acquired macular disorders, uveitis, neuro ophthalmology, hereditary fundus dystrophies, ocular tumours, vitreous opacities, strabismus, ophthalmic side effects of systemic medication, trauma.
620p
zizaybay1101
30-04-2024
3
2
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Part 1 book "Clinical imaging of spinal trauma - A case based approach" includes content: Normal variants and mimickers recommendations, pitfalls, and controversies - trauma to uncompromised spine (typically unstable, typically stable, soft tissue injuries).
101p
zizaybay1101
30-04-2024
2
2
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Part 2 book "Clinical imaging of spinal trauma - A case based approach" includes content: Thoracolumbar trauma classification, specifics of pediatric spinal trauma, trauma to compromised spine.
42p
zizaybay1101
30-04-2024
5
2
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Ebook "Strategies in regenerative medicine: Integrating biology with materials design" approach soon led to biomedical implants with improved clinical performances, but also to a new aspiration; rather than replacing damaged tissues and organs scientists and clinicians nowadays aim at their partial or complete regeneration. As a consequence of this ambition, the disciplines of tissue engineering and regenerative medicine have recently emerged.
515p
ladongphongthanh1008
22-04-2024
4
2
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Ebook "CFTR and cystic fibrosis: From structure to function" is devoted to the CFTR protein and cystic fibrosis, and it provides an updated perspective of the genetic, functional and cellular processes involved in this conformational disorder. Starting with a historical perspective on cystic fibrosis and its clinical features, the author departs into an in-depth description of the biology of the CFTR protein, ending with a discussion on the latest approaches aimed at developing corrective therapies for cystic fibrosis.
70p
tracanhphuonghoa1007
22-04-2024
3
2
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Part 1 book "Evidence-Based geriatric nursing protocols for best practice" includes content: Developing and evaluating clinical practice guidelines - A systematic approach; measuring performance, improving quality; age related changes in health; sensory changes; excessive sleepiness; assessment of physical function; interventions to prevent functional decline in the acute care setting; assessing cognitive function,... and other contents.
380p
muasambanhan10
03-04-2024
4
2
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A multi-disciplinary approach to promote engagement, inform decision-making and support clinicians and patients is increasingly advocated to realise the potential of genome-scale sequencing in the clinic for patient benefit. Here we describe the results of establishing a genomic medicine multi-disciplinary team (GM-MDT) for case selection, processing, interpretation and return of results.
12p
vibransone
28-03-2024
2
2
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Tumor cell-intrinsic mechanisms and complex interactions with the tumor microenvironment contribute to therapeutic failure via tumor evolution. It may be possible to overcome treatment resistance by developing a personalized approach against relapsing cancers based on a comprehensive analysis of cell typespecific transcriptomic changes over the clinical course of the disease using single-cell RNA sequencing (scRNA-seq).
21p
vibransone
28-03-2024
3
2
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Populations of closely related microbial strains can be simultaneously present in bacterial communities such as the human gut microbiome. We recently developed a de novo genome assembly approach that uses read cloud sequencing to provide more complete microbial genome drafts, enabling precise differentiation and tracking of strain-level dynamics across metagenomic samples.
17p
vibransone
28-03-2024
9
1
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Massively parallel DNA sequencing, such as exome sequencing, has become a routine clinical procedure to identify pathogenic variants responsible for a patient’s phenotype. Exome sequencing has the capability of reliably identifying inherited and de novo single-nucleotide variants, small insertions, and deletions.
11p
vioraclene
31-03-2024
3
1
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Precision medicine approaches are ideally suited for rare tumors where comprehensive characterization may have diagnostic, prognostic, and therapeutic value. We describe the clinical case and molecular characterization of an adolescent with metastatic poorly differentiated carcinoma (PDC).
17p
vioraclene
31-03-2024
8
1
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