Abnormal prothrombin

Factor VII deficiency is a rare inherited bleeding disorder that has similar clinical presentation to hemophilia. Even though factor VII deficiency is an extremely rare bleeding disorder, it does occur in our setting. This case highlights the need for clinicians to consider this condition when faced with challenging patients presenting with bleeding disorders.

4p vidoctorstrange 06-05-2023 2 2   Download

Several studies have reported that daptomycin induced artificial prolongation of prothrombin time (PT) in some test reagents, particularly in warfarin users. However, it remains unknown whether the artificial prolongation can be affected by coagulation abnormalities other than the use of warfarin.

5p vimax2711 30-03-2020 12 2   Download

Commonly used tests of hemostasis provide the initial screening for clotting factor activity (Fig. 110-1), and disease phenotype often correlates with the level of clotting activity. An isolated abnormal prothrombin time (PT) suggests FVII deficiency, whereas a prolonged activated partial thromboplastin time (aPTT) indicates most commonly hemophilia or FXI deficiency (Fig. 110-1). The prolongation of both PT and aPTT suggests deficiency of FV, FX, FII, or fibrinogen abnormalities.

5p thanhongan 07-12-2010 70 2   Download