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Glioblastoma (GBM) is a relatively prevalent primary tumor of the central nervous system in children, characterized by its high malignancy and mortality rates, along with the intricate challenges of achieving complete surgical resection. This study embarks on the task of evaluating the effectiveness of MZ1, an inhibitor of BRD4 meticulously designed to specifically target SEs, within the intricate framework of GBM.
19p
vikoch
27-06-2024
2
1
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In this research, a single-step polymeric novel particle was synthesized from oak bark extract by nanoemulsion polymerization technique for the first time in the literature. It has been shown that the synthesized particles are achieved without losing any antioxidant and antibacterial properties of the oak bark extract. In this study, the p(OB) particles were reported for the first time and were characterized in terms of antioxidant, blood compatible, H2O2 scavenging, antibacterial, and antifungal potential to evaluate their use in biocompatible materials with drug release system potential.
13p
dianmotminh02
03-05-2024
3
1
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Ebook "Cell death signaling in cancer biology and treatment" is to describe state-of-the-art approaches and future opportunities for achieving this goal by targeting mechanisms and pathways that regulate cancer cell death. In this book, molecular defects in cell death signaling that characterize cancer cells, including dysregulation of cell death due to overexpression/hyperactivation of oncoproteins, as well as the loss of tumor suppressor proteins will be described.
412p
tracanhphuonghoa1007
22-04-2024
3
1
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Based on shaking experiment results of a full-scale 4-story steel building conducted on E-Defense – the world largest shaking table in Japan, the characterization of twisting behavior can be achieved. Exploration on twisting motion of the specimen building is presented in this paper, addressing global rotational responses in various increasing excitation levels.
4p
visergey
02-04-2024
5
0
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Ebook "Photoelectrochemical water splitting: Standards, experimental methods, and protocols" outlines many of the techniques involved in materials development and characterization for photoelectrochemical (PEC) – for example, proper metrics for describing material performance, how to assemble testing cells and prepare materials for assessment of their properties, and how to perform the experimental measurements needed to achieve reliable results towards better scientific understanding.
130p
coduathanh1122
27-03-2024
2
1
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Ebook "Principles of polymer design and synthesis" aimed at the advanced undergraduate or graduate student, provides future scientists and engineers with the fundamental knowledge of polymer design and synthesis to achieve specific properties required in everyday applications. In the first five chapters, this book discusses the properties and characterization of polymers, since designing a polymer initially requires us to understand the effects of chemical structure on physical and chemical characteristics.
314p
coduathanh1122
27-03-2024
3
1
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Aplastic anemia is an intractable disease characterized by pancytopenia, susceptibility to infection, and difficulty in achieving hemostasis. In patients with severe periodontal disease and aplastic anemia, spontaneous bleeding from the gingival tissue due to thrombocytopenia and during brushing is common, which may further exacerbate dental issues.
8p
vilazada
31-01-2024
5
2
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Ebook "Polymer science: A comprehensive reference - Volume 6: Macromolecular architectures and soft nano-objects" focuses on several aspects of controlled macromolecular architectures and soft nano-objects including hybrids and bioconjugates. Many of the achievements would have not been possible without new characterization techniques like AFM that allowed direct imaging of single molecules and nano-objects with a precision available only recently.
844p
loivantrinh
29-10-2023
7
3
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The study aimed to isolate oil-degrading bacterial strains from the contaminated soil of Cam Ranh, Khanh Hoa, and develop a robust indigenous bacterial consortium for bioremediation of crude oil pollution. From a total of seven oil-polluted soil samples collected in Cam Ranh, after 3-fold enrichment in liquid mineral salt medium containing 5% crude oil mixed in diesel DO (w/v), 7 bacterial isolates were achieved.
8p
giangnhanly
02-10-2023
4
2
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Peyronie’s disease is a chronic inflammatory condition of the corpora cavernosa characterized by the formation of plaque in the tunica albuginea, which results in penile deformity. Conservative medical approaches encompass oral, topical, and physical treatment.
15p
vigamora
23-05-2023
9
2
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To achieve the aim, the first objective is preliminary experiments on preparation of polypropylene blends with silicone elastomer masterbatch and characterize by analysis of mass composition, mechanical properties, and dynamic mechanical properties to investigate any improvement of properties. The silicone elastomer masterbatch will then be substituted with propylene-maleic anhydride graft copolymer waxes or other compatibilizers.
147p
runthenight05
01-03-2023
4
2
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In this study, a new copolymer, which is a combination of two chemical structure (9,10-di(furan-2-yl)anthracene and 3,4-ethylenedioxythiophene was synthesized via electrochemical synthesis methods in the electrolyte medium of 0.1 M TBAPF6 / ACN solution. PEDOT homopolymer was also electrosynthesized for comparator experiments of the polymer formations in the same medium. The characterizations of polymers were achieved with general optical and electrochemical characterization techniques.
10p
lyhuyenthu
31-01-2023
7
2
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This study described the performance of carbon nanofiber modified chitosan (CNF@CS) composite microspheres for the controlled release of the Ibrutinib (IBR) drug. The surface morphology, particle sizes, and functional group contents of the microspheres were characterized by attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FTIR), scanning electron, and optical microscopy measurements.
10p
lyhuyenthu
31-01-2023
6
2
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Polysaccharides such as xanthan, locust bean gum or chitosan are easily crosslinked and purified using citric acid in an ecofriendly process. In order to achieve an improved sorption capability towards hydrophobic solutes, β-cyclodextrin, a cyclic oligosaccharide, and lignin, a natural aromatic polymer, are incorporated in the same process.
10p
viginny
30-12-2022
9
4
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Starch is a polysaccharide widely present in nature and characterized by a wide range of applications. This often implies the necessity for various novel properties with respect to those of native starch, mainly achievable via chemical modification.
19p
viginny
30-12-2022
12
2
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In this paper, cantilever beams are designed and fabricated on silicon wafers. L-Edit software is used to design two masks for light exposure step. Fabrication process including photolithography, copper thermal evaporation, and etching is done to achieve the designed cantilever beams.
8p
vifred
23-12-2022
17
3
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For high throughput native mass spectrometry (MS) protein characterization, it is advantageous to desalt and separate proteins by size exclusion chromatography (SEC). Sensitivity, resolution, and speed in these methods remain limited by standard SEC columns.
11p
vironald
15-12-2022
6
2
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In recent years with the explosion of research in artificial intelligence, deep learning models based on convolutional neural networks (CNNs) are one of the promising architectures for practical applications thanks to their reasonably good achievable accuracy. However, CNNs characterized by convolutional layers often have a large number of parameters and computational workload, leading to large energy consumption for training and network inference.
10p
vikissinger
03-03-2022
11
2
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Functional characterization of non-coding elements in the human genome is a major genomic challenge and the maturation of genome-editing technologies is revolutionizing our ability to achieve this task. Oncogene-induced senescence, a cellular state of irreversible proliferation arrest that is enforced following excessive oncogenic activity, is a major barrier against cancer transformation.
13p
vigalileogalilei
27-02-2022
10
1
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Technological limitations have hindered the large-scale genetic investigation of tandem repeats in disease. We show that long-read sequencing with a single Oxford Nanopore Technologies PromethION flow cell per individual achieves 30× human genome coverage and enables accurate assessment of tandem repeats including the 10,000-bp Alzheimer’s disease-associated ABCA7 VNTR.
16p
vielonmusk
30-01-2022
5
0
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