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Acute skin toxicity
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Large-scale trials have shown that hypofractionated adjuvant breast radiotherapy was as effective in terms of survival and local control as conventional fractionated radiotherapy, and acute toxicity was reduced with hypofractionated radiotherapy.
10p
vileonardodavinci
23-12-2023
3
2
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Radiotherapy of head-and-neck cancer (SCCHN) is often associated with acute toxicity. In a previous trial, daily reminders by staff members to perform skin care resulted in less dermatitis. This randomized trial investigated whether a mobile application can replace these reminders.
9p
vialfrednobel
23-12-2023
4
3
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Cancers of the head and neck region are often characterized by locally advanced, non-metastatic disease. Standard treatments for advanced cervico-facial cancers of the skin or primary head and neck squamous cell carcinoma (HNSCC) include combinations of surgery, radiation and chemotherapy, which are associated with high rates of acute toxicity and complications.
10p
vischultz
20-10-2023
3
2
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The skin is the largest organ of the human body consisting of several layers possessing different properties and performing different physiological functions. The loss of skin integrity caused by a trauma or disease may provoke acute physiological and immune disorders that may even be fatal.
5p
vihulk
28-07-2023
4
2
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To identify predictive factors of radiation-induced skin toxicity in breast cancer patients by the analysis of dosimetric and clinical factors. In our experience dose inhomogeneity underneath G2 – G3 skin reactions seems to be the most important predictor for acute skin damage and in these patients more complex treatment techniques should be considered to avoid skin damage.
9p
vijennie2711
29-09-2020
15
1
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After breast-conserving radiation therapy most patients experience acute skin toxicity to some degree. This may impair patients’ quality of life, cause pain and discomfort. In this study, we investigated treatment and patient-related factors, including genetic polymorphisms, that can modify the risk for severe radiation-induced skin toxicity in breast cancer patients.
9p
vilisa271
22-09-2020
18
1
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Most cancer patients are treated with radiotherapy, but the treatment can also damage the surrounding normal tissue. Acute skin damage from cancer radiotherapy diminishes patients’ quality of life, yet effective biological interventions for this damage are lacking.
16p
vilisa271
22-09-2020
24
1
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Morphological and histo-pathological effects of a common broad spectrum systemic organophosphate insecticide, Phorate (O, O-Diethyl S-(ethylthio) methyl phasphoroditl) were evaluated on the integument of an epigeic earthworm, Eisenia fetida. The acute toxicity experiments were conducted by direct contact test (48 h) through a filter paper method recommended by OECD Guideline, 207. The LC50 value for 48 h was recorded and it was 20-40µl.
6p
angicungduoc6
20-07-2020
14
1
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This study was conducted with an objective to determine the immunotoxic effect of sub acute exposure of selenium (Se) in broilers with special reference to the Dinitroflurobenzene (DNFB) contact skin sensitivity test and pathomorphological alterations in histoarchitecture of lymphoid organs. The chicks were intoxicated orally with sodium selenite @ 2, 6 and10 ppm respectively in diet, daily for 35 days. The present study exhibited significant depression of cell mediated immunity in Se treated broilers as measured by DNFB skin contact sensitization test.
7p
trinhthamhodang1213
30-05-2020
6
0
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There is lack of information regarding; the toxicological and pathological consequences of phenol stressed Clarias gariepinus; as well as; the susceptibility of the stressed fish to disease occurrence. Static renewal bioassay was experimentally conducted to evaluate the toxic effects of phenol on the African catfish C. gariepinus. Ninety-six-hour acute toxicity tests revealed that the median lethal concentration of phenol (LC50) is 35 mg/L by immersion.
7p
kethamoi1
17-11-2019
9
1
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Complications Following Hematopoietic Cell Transplant Early Direct Chemoradiotoxicities The transplant preparative regimens commonly used cause a spectrum of acute toxicities that vary according to the specific regimen but frequently result in nausea, vomiting, and mild skin erythema (Fig. 108-1). Regimens that include high-dose cyclophosphamide can result in hemorrhagic cystitis, which can usually be prevented by bladder irrigation or with the sulfhydryl compound mercaptoethanesulfonate (MESNA); rarely, acute hemorrhagic carditis is seen.
5p
thanhongan
07-12-2010
64
3
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