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Adenoviral vector
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Canine morbilivirus (canine distemper virus, CDV) is a highly contagious pathogen associated with high morbidity and mortality in susceptible carnivores. Although there are CDV vaccines available, the disease poses a huge threat to dogs and wildlife hosts due to vaccine failures and lack of effective treatment.
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vidarwin
23-02-2022
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Combining anti-cancer therapies with orthogonal modes of action, such as direct cytotoxicity and immunostimulatory, hold promise for expanding clinical benefit to patients with metastatic disease.
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vikuala271
13-06-2020
9
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One of the most commonly used vectors for gene therapy is the adenoviral vector; its ability to tightly regulate transgene expression is critical for optimizing therapeutic outcomes.
8p
viuchiha2711
21-04-2020
17
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Ever since their discovery adenoviruses have proven to be a tremendous asset to biologists. Through the study of the adenoviruses, we have learned not only about the virus structures, mechanisms of viral replication, but also about eukaryotic gene expression, alternative splicing, regulation of cell cycle progression, and apoptosis. In the last five years, there has been an explosion in the use of adenoviruses as vectors for gene transfer to a variety of mammalian cells.
334p
thuytienvang_1
31-10-2012
39
3
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The author also points out the exiting problems and obstacles in this field. In chapter seven, Adams et al. discuss how adenoviral vectors interact with human immune cells, particularly how adenoviral vectors interact with professional antigen presenting cells, namely dendritic cells. Chapter eight reviews the properties of the immune response induced by adenoviral vaccines and the mechanisms which control the quality of T cell response generated during such vaccination. Holst et al.
222p
kmkmkmkmkm
08-09-2012
44
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Adenoviral vectors serve as an excellent gene delivery system for a variety of cell types or organs for gene therapy and immunization applications. In the second section ‘Adenoviral Vector’, chapter five introduces the history of adenovirus research, the advantage and disadvantage of adenoviral vector, the adenoviral vector induced innate immune response, the evolution of adenoviral vector system, the application of adenoviral vector in gene therapy, and adenoviral vaccine.
340p
kmkmkmkmkm
08-09-2012
42
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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Molecular and macromolecular alterations of recombinant adenoviral vectors do not resolve changes in hepatic drug metabolism during infection
17p
dauphong7
13-01-2012
45
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Characterization of transgene expression in adenoviral vector-based HIV-1 vaccine candidates
7p
dauphong4
24-12-2011
38
2
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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Early Reversal of experimental colitis disease activity in mice following administration of an adenoviral IL-10 vector...
10p
thulanh27
13-12-2011
65
2
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Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: Improved gene delivery to human saphenous vein cells and tissue using a peptide-modified adenoviral vector Lorraine M Work1, Paul N Reynolds2 and Andrew H
0p
toshiba20
12-11-2011
52
2
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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: Improved vaccine protection against retrovirus infection after co-administration of adenoviral vectors encoding viral antigens and type I interferon subtypes...
15p
toshiba15
24-10-2011
32
2
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Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Comparison of osteogenic potentials of human rat BMP4 and BMP6 gene therapy using [E1-] and [E1-,E2b-] adenoviral vectors...
9p
thulanh9
07-10-2011
42
2
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Another local approach uses adenoviral-mediated expression of the tumor suppressor p53, which is mutated in a wide variety of cancers. This strategy has shown complete and partial responses in squamous cell carcinoma of the head and neck, esophageal cancer, and non-small cell lung cancer after direct intratumoral injection of the vector. Response rates (~15%) are comparable to those of other single agents.
5p
konheokonmummim
03-12-2010
65
4
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