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Adrenergic drugs
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Increases in α-synuclein protein expression are suspected to increase the risk of the development of Parkinson’s disease (PD). A recent study has demonstrated that β2-adrenergic receptor (β2AR) agonists decrease histone acetylation in the α-synuclein gene and suppress transcription.
3p
vioraclene
31-03-2024
3
2
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Part 1 book "Veterinary anesthesia and analgesia - The fifth edition of lumb and jones" includes content: Anesthetic risk and informed consent, anesthesia equipment, monitoring anesthetized patients, anesthetic emergencies and resuscitation, euthanasia and humane killing, general pharmacology of anesthetic and analgesic drugs, anticholinergics, adrenergic agents, sedatives and tranquilizers, opioids, non steroidal anti inflammatory drugs,... and other contents.
568p
muasambanhan02
18-12-2023
2
0
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Ritodrine, a tocolytic β2-agonist, has been used extensively in Europe and Asia despite its safety concerns. This study was designed to identify associations between β2-adrenergic receptor (ADRB2) polymorphisms and adverse drug events (ADEs) in patients with preterm labor treated with ritodrine.
6p
vinarcissa
21-03-2023
2
1
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This was investigated for the enantioslective separation of different classes of pharmaceuticals namely - and -blockers, anti-inflammatory and antifungal drugs, norepinephrine-dopamine reuptake inhibitor, catecholamines, sedative hypnotics, anti-histaminics, anticancer drugs, antiarrhythmic drugs, flavonoids, amino acids, alpha-2 adrenergic agonist, adrenaline and miscellaneous.
9p
viginny
23-12-2022
6
3
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Ovarian chronic inflammation has been known to incidence in the laying hen mainly via increasing laying frequency and microbial infection, especially during late stage of production period. This study was aimed to evaluate beta-2 adrenergic agonist (Beta-2 Adrenergic Agonist, BAA) Salmeterol and beta blocker (Beta Blocker, BB).
13p
vidarwin
23-02-2022
9
1
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Catecholamines are the first-line vasopressors used in patients with septic shock. However, the search for novel drug candidates is still of great importance due to the development of adrenergic hyposensitivity accompanied by a decrease in catecholamine activity. Terlipressin (TP) is a synthetic vasopressin analogue used in the management of patients with septic shock. In the current study, we aimed to compare the effects of TP and catecholamine infusion in treating septic shock patients.
8p
vizhangzhidong
29-12-2021
7
0
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After the SMART trial evaluating the safety of salmeterol (long-acting beta-2-agonist (LABA)) in asthma patients, regulatory actions were taken to promote a guideline-adherent prescribing of LABA only to patients receiving inhaled corticosteroids (ICS). We aim to analyse LABA- and ICS-related prescription patterns after the SMART trial in Germany.
10p
vimontana2711
05-04-2021
12
2
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Salbutamol-induced lactic acidosis is a rare presentation that could manifest in specific clinical context as acute asthmatic attack treatment. An increase of glycolysis pathway leading to pyruvate escalation is the mechanism of hyperlactatemia in β2-adrenergic agonist drug.
4p
vimichigan2711
26-03-2021
8
2
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Repurposing existing medications for antineoplastic purposes can provide a safe, cost-effective, and efficacious means to further augment available cancer care. Clinical and preclinical studies suggest a role for the ßadrenergic antagonist (ß-blocker) propranolol in reducing rates of tumor progression in both solid and hematologic malignancies.
12p
vibaku2711
22-07-2020
20
2
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Clonidine is an imidazoline sympatholytic, acting on both α2-adrenergic and imidazoline receptors in the brainstem to induce antihypertensive and negative chronotropic effects in the vasculature and heart respectively.
4p
vimax2711
30-03-2020
11
2
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Timolol maleate (TiM), a nonselective b-adrenergic blocker, is a potent highly effective agent for management of hypertension. The drug suffers from extensive first pass effect, resulting in a reduction of oral bioavailability (F%) to 50% and a short elimination half-life of 4 h; parameters necessitating its frequent administration. The current study was therefore, designed to formulate and optimize the transfersomal TiM gel for transdermal delivery.
11p
kequaidan1
16-11-2019
19
2
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(bq) part 1 book "pharmacology for health professionals" presentation of content: foundations of clinical pharmacology, drugs that affect the central nervous system, drugs that affect the peripheral nervous system.
262p
thangnamvoiva23
06-10-2016
42
6
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(BQ) Part 1 of the document Cardiovascular pharmacotherapeutics presents the following contents: Basic principles of clinical pharmacology relevant to cardiology, the placebo effect in the treatment of cardiovascular disease, health economic considerations in cardiovascular drug utilization, Alpha-and Beta-Adrenergic blocking drugs,..
492p
thangnamvoiva4
01-07-2016
52
4
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(BQ) Continued part 1, part 2 of the document Textbook of organic medicinal and pharmaceutical chemistry presents the following contents: Centralnervous system depressants, central dopaminergic signaling agents, anticonvulsants, central nervous system stimulants, adrenergic agents, drugs acting on the renal system,...
568p
thangnamvoiva3
28-06-2016
60
6
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Adrenergic receptors (ARs) are expressed in almost all organs and tissues and regulate a large number of diverse physiological processes upon activation by epinephrine and norepinephrine. There are three families of ARs, a1, a2, and b-ARs, with distinct pharmacological properties and functions. Since the first identification of bARs more than three decades ago, research on ARs has led to the establishment of many fundamental concepts in G protein-coupled receptor (GPCR) pharmacology.
0p
hotmoingay
04-01-2013
62
2
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Phenylephrine, hệ thống (Neo-Synephrine) Chú ý: sĩ nên lưu ý về Trước khi sử dụng Sử dụng thông tin đầy đủ Quy định: * Mạch thất bại trong dị ứng, sốc, hoặc do thuốc ↓ BP * Hành động: α-adrenergic chủ vận Liều lượng: Người lớn. Nhẹ trung bình ↓ BP: 2-5 mg IM hay SQ ↑ BP trong 2 h, 0,1-0,5 mg IV nâng BP trong 15 phút.
32p
meomap9
26-12-2011
75
3
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Anyone who administers drugs acting on cardiovascular adrenergic mechanisms requires an understanding of how they act in order to use them to the best advantage and with safety. Adrenergic mechanisms Classification of sympathomimetics: by mode of action and selectivity for adrenoceptors Individual sympathomimetics Mucosal decongestants Shock Chronic orthostatic hypotension Adrenaline, noradrenaline and dopamine are formed in the body and are used in therapeutics. The natural synthetic path is: tyrosine — dopa — dopamine — noradrenaline — adrenaline.
13p
bigbaby87
03-09-2010
85
9
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Introductio: β-Blockers (β-adrenergic receptor antagonists) block the effects of catecholamines on signal transmission through β-receptors; they cause hypotension by decreasing the heart beat rate and cardiac output, and prevent the attacks of arrhythmia and angina pectoris. In the brain, the drugs attenuate migraine by suppressing the dilation of blood vessels; in the eye, they decrease intraocular pressure by suppressing the production of aqueous humor.
8p
bigbaby87
01-09-2010
105
7
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