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Adult patients
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This study aimed to assess lower limb strength and some related factors among older people with dementia examined and treated at the National Geriatric Hospital. Three-quarters of older dementia patients have impaired lower limb strength. Our results highlighted that diabetes, and geriatric syndromes such as malnutrition, high fall risk, dependence, and partial dependence were significantly associated with lower limb strength in older patients with dementia.
9p
vikoch
27-06-2024
1
1
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The aim of this study was to assess the knowledge, attitudes, and practices regarding cancer prevention, and associated characteristics to inform the development of targeted cancer prevention campaigns and policies.
10p
vishanshan
27-06-2024
1
1
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Glioblastoma (GBM) is the most common adult malignant brain tumour, with an incidence of 5 per 100,000 per year in England. Patients with tumours showing O6 -methylguanine-DNA methyltransferase (MGMT) promoter methylation represent around 40% of newly diagnosed GBM.
12p
vishanshan
27-06-2024
1
1
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Glioblastoma is the most common and most aggressive malignant primary brain tumor in adults. Glioblastoma cells synthesize and secrete large quantities of the excitatory neurotransmitter glutamate, driving epilepsy, neuronal death, tumor growth and invasion.
7p
vishanshan
27-06-2024
2
1
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Despite advancements in managing metastatic clear cell renal carcinoma (mccRCC) through antiangiogenic tyrosine kinase inhibitors and immunotherapy, there remains a demand for novel treatments for patients experiencing progression despite the use of these medications.
8p
vishanshan
27-06-2024
2
1
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Adolescents and young adults (AYAs) with cancer, defined as individuals aged 15–39 years at initial cancer diagnosis, form a unique population; they face age-specific issues as they transition to adulthood. This paper presents the protocol for the development of a core outcome set (COS) for AYAs with cancer
12p
vishanshan
27-06-2024
1
1
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In 2016, Uganda added Hydroxyurea (HU) to the list of essential drugs to treat sickle cell disease SCD. However, Hydroxyurea utilization has been low for several countries in sub-Saharan Africa. This study examined patient-related barriers to hydroxyurea use among adolescent and adult patients with sickle cell disease in Mulago and Kiruddu hospitals, in Uganda.
18p
vishanshan
27-06-2024
1
1
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This can be particularly useful for older, frail patients to better tolerate surgery. The aim of this study was to identify what barriers and facilitators healthcare professionals in Germany experienced in the implementation and delivery of the multimodal prehabilitation programme “PRAEP-GO” for (pre-) frail adults aged 70 years and older to inform the implementation of prehabilitation into standard care.
12p
vishanshan
27-06-2024
1
1
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This study focuses on the geographical areas of the four communities where RaDAR memory clinics were first developed and implemented and describes the services and supports available to older adults including memory clinic patients and families living in these areas.
13p
vishanshan
27-06-2024
1
1
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Health professionals in Colombian and many parts of the world, in some cases, work in precarious conditions and intend to migrate to other countries in search of better living conditions for themselves and their families, which results in inadequate distribution worldwide and in the quality of care throughout the health system, which can ultimately influence the quality of life of patients in their health-disease processes.
12p
vishanshan
27-06-2024
1
1
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The growing number of older adults with chronic diseases challenges already strained healthcare systems. Fragmented systems make transitions between healthcare settings demanding, posing risks during transitions from in-patient care to home. Despite efforts to make healthcare person-centered during care transitions, previous research indicates that these ambitions are not yet achieved.
10p
vishanshan
27-06-2024
1
1
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Patient satisfaction is an important indicator of the quality of healthcare. Pain is one of the most common symptoms among cancer patients that needs optimal treatment; rather, it compromises the quality of life of patients.
9p
vishanshan
27-06-2024
1
1
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It is unclear whether hepatectomy, which ranges in invasiveness from partial to major hepatectomy, is safe and feasible for older adult patients. Therefore, we compared its postoperative complications and long-term outcomes between younger and older adult patients.
13p
vikoch
27-06-2024
1
1
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Gliomas are the deadliest malignant tumors of the adult central nervous system. We previously discovered that beta2-microglobulin (B2M) is abnormally upregulated in glioma tissues and that it exerts a range of oncogenic effects. Besides its tissue presence, serum B2M levels serve as biomarkers for various diseases. This study aimed to explore whether serum B2M levels can be used in the diagnosis and prognosis of gliomas.
10p
vikoch
27-06-2024
1
1
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Patients at risk of skin cancers can develop varying types of cutaneous malignancies. However, some subjects may develop only one type of lesion. In this cross-sectional study, the spectrum of premalignant (PM) and malignant skin lesions and their risk factors were studied.
13p
vikoch
27-06-2024
1
1
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Screening of cancer is the maximum effort and critical element for providing health related care in order to decrease cancer related dealt because of the disease burden is in its advanced stages. Unfortunately, advanced-stage presentation and late diagnosis of cancers endure a problem in low-income countries including Ethiopia. However, there is scarcity of published articles about the problem in Ethiopia.
8p
vikoch
27-06-2024
1
1
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Pediatric low-grade glioma (pLGG) is essentially a single pathway disease, with most tumors driven by genomic alterations affecting the mitogen-activated protein kinase/ERK (MAPK) pathway, predominantly KIAA1549::BRAF fusions and BRAF V600E mutations. This makes pLGG an ideal candidate for MAPK pathway-targeted treatments.
11p
vikoch
27-06-2024
1
1
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This handbook describes the perioperative management of adult patients who undergo cardiac surgery at our centre. Although it was written by numerous authors, each chapter was carefully edited to reflect the collective view of our health care team.
281p
vimeyers
29-05-2024
3
2
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Hypertension is prevalent in the elderly, affecting two-thirds of individuals aged 60 years and older. Ambulatory blood pressure measurement (ABPM) is recommended for diagnosing and managing hypertension in this population. This study aimed to characterize 24-hour ABPM profiles and their association with cardiovascular risk factors in older adults with high-risk hypertension.
10p
viambani
21-05-2024
3
2
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Measles is an acute infectious disease which occurs in children and adults who are not immune to measles. However, adult patients with measles often have more severe symptoms than children. Description of the clinical and subclinical features, complications, and some related factors to complications of adult patients with measles.
8p
vicarlos
16-05-2024
1
0
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