Advanced breast cancer

The purpose of this phase II study was to evaluate the feasibility of hypofractionated radiotherapy (HFRT) with a dose of 36.5Gy in 10 fractions in postmastectomy patients. From March 2014 to December 2015, 85 patients with locally advanced breast cancer were eligible to participate in this study with a schedule of 36.5Gy in 10 fractions.

8p vielonmusk 21-01-2022 11 1   Download

The ESR1 gene encodes Estrogen Receptor alpha (ERα), which plays a role in the tumourigenesis of breast cancer. A single nucleotide polymorphism (SNP) in intron 1 of this gene called ESR1 PvuII (rs2234693) has been reported to increase the risk of breast cancer. This study aimed to investigate the ESR1 PvuII polymorphism as a prognostic and predictive factor guiding the choice of therapy for advanced breast cancer.

7p vielonmusk 21-01-2022 39 1   Download

To investigate the prognostic value of derived neutrophil to lymphocyte ratio (dNLR) and lactate dehydrogenase (LDH) in patients with advanced HER2 positive breast cancer treated with trastuzumab emtansine.

13p vielonmusk 21-01-2022 18 1   Download

Eribulin methylate (eribulin) improved the overall survival (OS) of eribulin-treated patients with HER2- negative advanced breast cancer (ABC) in prospective and retrospective studies. However, the effect of eribulin on OS as first-line chemotherapy and the characteristics of the patients who benefited from eribulin remain unclear.

10p vielonmusk 21-01-2022 16 1   Download

Trastuzumab and fulvestrant combination therapy is one of the treatment options for patients with hormone receptor- and human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer; however, there are limited studies evaluating the efficacy of this combination therapy.

7p vielonmusk 21-01-2022 18 1   Download

Methylglyoxal is the most important intracellular glycation agent, formed nonenzymatically from triose phosphates during glycolysis in eukaryotic cells. Methylglyoxal-derived advanced glycation end-products are involved in neurodegenerative disorders (Alzheimer’s, Parkinson’s and familial amy-loidotic polyneurophathy) and in the clinical complications of diabetes.

11p fptmusic 12-04-2013 43 2   Download

NMR studies on the interaction of sugars with the C-terminal domain of an R-type lectin from the earthworm Lumbricus terrestris Hikaru Hemmi1, Atsushi Kuno2, Shigeyasu Ito2,3, Ryuichiro Suzuki2,3, Tsunemi Hasegawa3 and Jun Hirabayashi2 1 National Food Research Institute, National Agriculture and Food Research Organization (NARO), Tsukuba, Japan 2 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan 3 Department of Material and Biological Chemistry, Yamagata University, Yamagata, Japan Keywords earthworm Lumbricus ...

11p viettel02 22-02-2013 76 3   Download

The BCL-2 homology domain 3 (BH3)-only protein, B-cell lymphoma 2 interacting mediator of cell death (BIM) is a potent pro-apoptotic protein belonging to the B-cell lymphoma 2 protein family. In recent years, advances in basic biology have provided a clearer picture of how BIM kills cells and how BIM expression and activity are repressed by growth factor signalling pathways, especially the extracellular signal-regulated kinase 1⁄2 and protein kinase B pathways.

13p viettel02 20-02-2013 39 1   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Magnitude of risks and benefits of the addition of bevacizumab to chemotherapy for advanced breast cancer patients: Meta-regression analysis of randomized trials

9p toshiba22 21-11-2011 61 3   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Evaluation of HER2 and p53 expression in predicting response to docetaxel-based first-line chemotherapy in advanced breast cancer

9p toshiba22 21-11-2011 54 5   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Radiation therapy planning with photons and protons for early and advanced breast cancer: an overview...

11p toshiba10 15-10-2011 56 2   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: "Concurrent chemo-radiotherapy following neoadjuvant chemotherapy in locally advanced breast cancer...

8p toshiba10 15-10-2011 43 4   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: "Constitutive gene expression profile segregates toxicity in locally advanced breast cancer patients treated with high-dose hyperfractionated radical radiotherapy...

7p toshiba10 15-10-2011 52 2   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: Radiation induced apoptosis and initial DNA damage are inversely related in locally advanced breast cancer patients...

5p toshiba9 14-10-2011 43 3   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Recent advances in the surgical care of breast cancer patients

17p matuot_238 12-10-2011 51 4   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Sentinel lymph node biopsy using dye alone method is reliable and accurate even after neo-adjuvant chemotherapy in locally advanced breast cancer - a prospective study

7p hoami_238 11-10-2011 46 5   Download

Making a Treatment Plan From information on the extent of disease and the prognosis and in conjunction with the patient's wishes, it is determined whether the treatment approach should be curative or palliative in intent. Cooperation among the various professionals involved in cancer treatment is of the utmost importance in treatment planning.

5p konheokonmummim 03-12-2010 72 4   Download