Advances in experimental medicine and biology

The book provides comprehensive overviews on the diversity of biosurfactant-producing microorganisms and types of biosurfactant molecules that are made. Also, the book includes a state-of-the-art discussion on the use of alternative substrates and fermentation approaches for biosurfactant production.

361p vimeyers 29-05-2024 3 2   Download

Ebook "TNF receptor associated factors (TRAFs)" is the only literature that is entirely devoted to TRAFs. Almost every aspect of TRAF signaling is covered, including the different TRAF family members, their distinct biological functions, the TRAF structures, their modes of receptor recognition, the signaling mechanisms, and the roles of TRAFs in normal cellular functions and in viral infection.

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Ebook "Current topics in complement II" to discuss recent advances in this rapidly-evolving field. This volume represents a collection of topics on the “novel” functions of complement, pathophysiology, protein structures, and complement therapeutics discussed during the conference.

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Ebook "Relaxin and related peptides" discusses the established paradigms, the contradictions, and the most recent findings and future directions in the field of relaxin research. The array of diverse topics are highlighted, ranging from evolution of relaxin family peptides and receptors to their cell signaling, from the role of relaxin in reproduction to the newly discovered functions in cancer progression and in the nervous system.

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Ebook "Breast cancer chemosensitivity" include in-depth discussions on multidrug resistance by P-glycoprotein and the multidrug resistance protein family, resistance to therapeutic agent-induced apoptosis, cell cycle deregulation, deregulation of DNA repair, loss of tumor suppressor genes, integrin-mediated adhesion, insulin-like growth factors, epidermal growth factor, and ErbB2 in modulating breast cancer response to systemic therapy, especially, certain chemotherapeutic agents.

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Ebook "Early life origins of health and disease" is a new book which presents and discusses the many factors that may have impact on normal development. In a concise and readable manner, the authors consider both the proven and suggestive evidence that the high prevalence of hypertension, diabetes, obesity and, in some populations, kidney disease, may not be all due to genetics or adult environment alone.

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In ebook "Genome instability in cancer development" studies on animal tumour viruses and chromosome rearrangements in human tumours have concurred to identify so-called ‘proto-oncogenes’ and ‘tumour suppressor genes’, whose deregulation promotes carcinogenesis. These important findings not only explain the occurrence of certain hereditary tumours, but they also set the stage for the development of anti-cancer drugs that specifically target activated oncogenes.

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Ebook "Adhesion-GPCRs: Structure to function" have made a courageous effort to address the key concepts of adhesion-GPCR biology, including the evolution and biochemistry of adhesion-GPCRs; there are extensive discussions on the functional nature of these receptors during development, the immune response and tumourgenesis. Finally, there are chapters dedicated to adhesion-GPCR signalling, an area of intense investigation.

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Ebook "RNA exosome" is arising as a major facilitator to this effect. Structural and functional data gathered over the last decade have illustrated the biochemical importance of this multimeric complex and its many co-factors, revealing its enormous regulatory power. By gathering some of the most prominent researchers in the exosome field, it is the aim of this volume to introduce this fascinating protein complex as well as to give a timely and rich account of its many functions.

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Ebook "RAMPs (Advances in experimental medicine and biology, Volume 744)" provides a general introduction to RAMPs including its discovery. The second chapter (by Poyner and colleagues) and the third chapter (by Bomberger and colleagues) are intended to provide in depth discussion on how the different RAMP isoforms can regulate various aspects of receptor signaling especially stimulated with calcitonin gene related peptide (CGRP) and adrenomedullin. In addition, in the third chapter, Bomberger et al discuss the differences in RAMP2 and -3 with regard to their role in receptor trafficking.

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Ebook "Protein metabolism and homeostasis in aging (Advances in experimental medicine and biology, Volume 694)" provided of the current knowledge in the area, including protein synthesis, accuracy and repair, post-translational modifications, degradation and turnover, and how they define and influence aging. The chapters mainly focus on well-characterised factors and pathways, but new areas are also presented, where associations with aging are just being elucidated by current experimental data.

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Ebook "Prokaryotic systems biology (Advances in experimental medicine and biology, Volume 883)" focuses on innovative experimental and computational approaches for charting interaction networks in bacterial species.

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Ebook "Proteomic methods in neuropsychiatric research (Advances in experimental medicine and biology, Volume 974)" will be of high interest to clinical scientists, physicians and pharmaceutical company scientists as it gives insights into the latest technologies enabling the revolution of personalized medicine. It is of direct interest to both technical and bench biomarker scientists as it gives step by step instructions on how to carry out each of the protocols.

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Ebook "Digenetic trematodes (Advances in experimental medicine and biology, Volume 766)" is to present the major trematodes and their corresponding diseases in the framework of modern parasitology, considering matters such as the application of novel techniques and analysis of data in the context of host-parasite interactions and to show applications of new techniques and concepts for the studies on digenetic trematodes.

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Ebook "Crossroads between innate and adaptive immunity IV (Advances in experimental medicine and biology, Volume 785)" presents a collection of reviews derived from work presented at the Aegean Conference: “4th Crossroads between innate and adaptive immunity”. This meeting was the fourth in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity.

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Ebook "Retinal degenerative diseases: Laboratory and therapeutic investigations (Advances in experimental medicine and biology, Volume 664)" provides readers with contents including: basic science underlying retinal degeneration; molecular genetics and candidate genes; diagnostic, clinical, cytopathological and physiologic aspects of retinal degeneration; macular degeneration;...

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Ebook "Transgenic microalgae as green cell factories (Advances in experimental medicine and biology, Volume 616)" book includes chapters focussing on biotechnological applications of transgenic microalgae. The enormous amount information generated by the genomic or cDNA sequencing projects and its implications on the development of new biotechnological applications of microalgae are analysed in Chapter 6.

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Ebook "Programmed cell death in cancer progression and therapy (Advances in experimental medicine and biology, Volume 615)" give a comprehensive overview of the mechanisms that are involved in mediating and regulating PCD in cancer. We also provide a detailed indication of the utility of PCD in cancer therapy. This book will be a valuable resource for researchers investigating the role of PCD in cancer and other diseases, researchers investigating the molecular mechanism of chemotherapeutic agents and drug-resistance in cancer and for physicians using chemotherapeutic agents.

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Ebook "Advances in food mycology (Advances in experimental medicine and biology, Volume 571)" was attended by some 35 participants, drawn from among food mycology and related disciplines around the world. The workshop was highly successful, with papers devoted to media and methods development in food mycology, as is usual with these workshops. Particular emphasis was placed on the fungi which produce mycotoxins, especially their ecology, and through ecology, potential control measures.

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Ebook "Bioactive components of milk (Advances in experimental medicine and biology, Volume 606)" is divided into four parts. The first part focuses on bioactive milk lipid components, which very widely among mammalian species. The second part describes different aspects of biological active colostrums and milk proteins and their derivatives, with special concern on species specific effects.

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