Adverse effects

Pharmacological treatments, primarily oral NSAIDs, constituted 73.9% usage for knee osteoarthritis. Despite the known adverse effects of NSAIDs, they are recommended for KOA management. This study aimed to analyze the cost-effectiveness of hyaluronic acid injections relative to oral medication treatment in patients with KOA from health insurance payer’s perspective.

11p viwalton 02-07-2024 0 0   Download

Patients with hematological malignancies often require multidrug therapy using a variety of antineoplastic agents and supportive care medications. This increases the risk of drug-related problems (DRPs). Determining DRPs in patients hospitalized in hematology services is important for patients to achieve their drug treatment goals and prevent adverse effects.

8p vishanshan 27-06-2024 1 1   Download

Lung adenocarcinoma, a leading cause of cancer-related mortality, demands precise prognostic indicators for effective management. The presence of spread through air space (STAS) indicates adverse tumor behavior.

12p vishanshan 27-06-2024 2 1   Download

Immune checkpoint inhibitors (ICI) combined with chemotherapy are efficacious for treating advanced non-small cell lung cancer (NSCLC); however, the effectiveness of this approach in the malignant pleural effusion (MPE) population is unclear. This study evaluated ICI plus chemotherapy in NSCLC patients with MPE.

9p vishanshan 27-06-2024 1 1   Download

Nervous system toxicity (NST) is one of the most frequent and dangerous side effects of chimeric antigen receptor T-cell (CAR-T) therapy, which is an effective treatment for related tumors in most relapsed/refractory (r/r) hematologic malignancies. Current clinical trial data do not fully reflect the real-world situation. Therefore, this study evaluated the NST of CAR-T therapy using the FDA Adverse Event Reporting System (FAERS).

11p vishanshan 27-06-2024 2 1   Download

This study’s goal was to assess the most prevalent short-term side effects experienced by patients with localized breast cancer, undergoing chemotherapy based on anthracyclines and taxane-containing treatments, at the medical oncology department of the Mohammed VI University Hospital of Marrakech, Morocco.

8p vishanshan 27-06-2024 1 1   Download

The implementation time of continuous nursing improvement based on the direct reporting system was the demarcation point. We retrospectively collected and analyzed nursing adverse event reports and hospitalization data from Xiangtan Central Hospital before implementation (2015–2018) and after implementation (2019–2022).

7p vishanshan 27-06-2024 1 1   Download

Adherence to chemotherapy treatment is recognized as a crucial health concern, especially in managing cancer patients. Chemotherapy presents challenges for patients, as it can lead to potential side effects that may adversely affect their mobility and overall function.

6p vishanshan 27-06-2024 3 1   Download

Recent advances in the management of pancreatic neuroendocrine tumors (pNETs) highlight the potential benefits of temozolomide, an alkylating agent, for these patients. In this meta-analysis, we aimed to assess the outcome of temozolomide, alone or in combination with other anticancer medications in patients with advanced pNET.

15p vikoch 27-06-2024 1 1   Download

Recently, propolis has shown potential cardioprotective effects against myocardial infarction. However, challenges in its clinical application have arisen, primarily due to concerns regarding dosage and potential adverse effects. To address this, we suggest integrating propolis into polyvinyl alcohol (PVA)/gelatin hydrogel to regulate the localized release of propolis at infarcted sites.

7p visergeyne 18-06-2024 0 0   Download

The objective of this study is to evaluate the impact of financial development on financial inclusion in Vietnam. Using data from the General Statistics Office and the World Bank, and through quantitative analysis, research results show that attracting FDI capital flows has a positive impact on financial inclusion. Furthermore, economic growth helps comprehensive financial development. However, financial development does not have a clear relationship with financial inclusion. In some cases, international trade can have an adverse effect on financial inclusion.

6p leminhvu111 07-06-2024 0 0   Download

This leading textbook in the field examines the mechanisms underlying toxicity, particularly the events at the molecular level and the factors that determine and affect toxicity. The new edition is updated to reflect the latest research into the biochemical basis of toxicology and the growing concerns over the adverse effects of drugs, environmental pollution, and occupational hazards.

467p vimeyers 29-05-2024 4 2   Download

The concept of sustainability has been widely accepted in tourism to minimize the adverse effects of tourism. This study aims to develop a comprehensive set of indicators to help assess progress toward sustainable tourism for development in Kien Giang, Vietnam.

19p viohoyo 25-04-2024 3 1   Download

This research aims to find out: (1) the more effective learning model on students' divergent-thinking skills; (2) the better adversity quotient on students' divergent-thinking skills; (3) the better adversity quotient to improve students' divergent-thinking skills in each learning model; and (4) the better learning model to improve students' divergent-thinking skills in each adversity quotient.

12p viarnault 25-04-2024 2 1   Download

This research aims to analyze the effects of intelligence quotient, emotional quotient, spiritual quotient, and adversity quotient on the graduates quality of vocational higher education. Data were collected from 217 cadets at Surabaya Shipping Polytechnic who already took an internship as respondents using stratified cluster random technique.

13p viarnault 25-04-2024 1 1   Download

Legislative body and judicial ruling enrols the law for human resource management, this law is generally refereed as legal context. It is quite comprehensive and complex context. It is applicable for handling the discrimination of employment and labours. This paper presents the detail of legal context of administration of law in the Jordan country . It also studies and compare law system with other countries. This research concentrates on the validity standards and laws which are used in legal context. Features of ethics and privacy related to the human resource management is discussed.

10p longtimenosee07 29-03-2024 5 2   Download

Variability in drug efficacy and adverse effects are observed in clinical practice. While the extent of genetic variability in classic pharmacokinetic genes is rather well understood, the role of genetic variation in drug targets is typically less studied.

15p vioraclene 31-03-2024 4 1   Download

Available anti-ulcer drugs unveil partial effectiveness and numerous adverse reactions. The present study investigated the possible protective effect of the herbal formulation Vien Khoi Tim (VKT) on indomethacininduced gastric mucosal damage in rats.

9p vilarry 12-03-2024 3 2   Download

In recent decades, cannabis has been widely used around the world for medical and recreational purposes, both legally and illegally. Aside from its therapeutic benefits, cannabis exhibits many adverse effects. Psychosis is one of the potentially harmful effects of cannabis.

4p vigojek 02-02-2024 2 1   Download

Nivolumab is an immune checkpoint inhibitor that blocks inhibitors of T-cell activation and blunts antitumor immunity and is used in the treatment of various cancers. However, immune checkpoint inhibitors have immune-related adverse effects on various organs due to promoting T-cell activity against host tissues by blocking inhibition of T-cell function.

5p vigojek 02-02-2024 3 1   Download