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Aged rats
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Bệnh gan do rượu bao gồm nhiều rối loạn lâm sàng: gan nhiễm mỡ do rượu, viêm gan do rượu (Alcoholic hepatitis - AH) các mức độ, xơ gan rượu (Alcoholic cirrhosis - AC) đi kèm các biến chứng của nó và viêm gan rượu cấp tính biểu hiện như đợt cấp suy gan mạn, gây nên bởi việc sử dụng rượu kéo dài1 . Có rất nhiều các chỉ số để đánh giá tiên lượng bệnh nhân bệnh gan do rượu, trong đó thang điểm ABIC được sử dụng ngày càng rộng rãi. Mục tiêu: Khảo sát giá trị thang điểm ABIC trong tiên lượng bệnh gan mạn do rượu.
5p
vigrab
28-02-2024
8
1
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There has been considerable interest in discovery of the genetic architecture of complex traits, particularly age-related neurodegenerative disorders. To predict disease risk and to understand its genetic basis in humans, it is necessary to study animal models.
17p
vinarcissa
21-03-2023
3
1
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Caloric restriction (CR) can increase longevity in rodents and improve memory function in humans. α-Lipoic acid (LA) has been shown to improve memory function in rats, but not longevity. While studies have looked at survival in rodents after switching from one diet to another, the underlying mechanisms of the beneficial effects of CR and LA supplementation are unknown.
18p
viaristotle
29-01-2022
12
0
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To investigate the role of IL-17A in the neuroinflammation and cognitive function of aged rats anaesthetized with sevoflurane through NF-κB pathway. Anti-IL-17A may alleviate neuroinflammation and oxidative stress via inhibiting NF-κB pathway, thereby attenuating post-operative cognitive dysfunction (POCD) in aged rats anaesthetized with sevoflurane.
9p
vampires36
30-12-2021
9
0
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Calcineurin (CaN) having a high expression in hippocampal neurons is closely related to apoptosis. Pretreatment with nimodipine can lower the apoptosis rate of hippocampal neuron to reduce the incidence of postoperative cognitive dysfunction (POCD).
7p
vampires36
30-12-2021
4
0
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This study aimed to evaluate effects of electric vagal nerve stimulation on early postoperation cognitive dysfunction in aged rats. Methods: A total of 33 male Sprague Dawley rats were selected and assigned randomly to three groups, control group (C, n = 10), splenectomy group (S, n = 10) and splenectomy+vagal nerve stimulation group (SV, n = 13).
11p
vizhangzhidong
29-12-2021
4
0
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Desflurane impairs hippocampal learning on day 1 of exposure: A prospective laboratory study in rats
Quick and complete recovery of cognitive function after general anesthesia is desirable, particularly for working-age patients. Desflurane is less likely to have long-term effects than older-generation inhalational anesthetics, however, its short-term effects have not been fully investigated. Our objective was to elucidate the short-term effects of desflurane exposure on learning and memory in young adult rats.
8p
vizhangzhidong
29-12-2021
7
0
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The mechanism of volatile anesthetics on vascular smooth muscle (VSM) contraction in the setting of diabetes mellitus (DM) remains unclear. The current study was designed to determine the efects of sevofurane (SEVO) and isofurane (ISO) on phosphoinositide 3-kinase (PI3K) and Rho kinase (ROCK) mediated KCl-induced vasoconstriction in aged type 2 diabetic rats.
8p
vidietmarhopp
29-12-2021
13
0
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The aim of the present study was to clarify the effects of silymarin on experimental testicular ischemia / reperfusion injury. A total of 40 Wistar albino rats (10–12 weeks of age, weighing 280–300 g) were randomly divided into five groups. Control group: No surgical procedures were performed. Torsion 3 h / detorsion 3 h group; torsion 3 h / detorsion 24 h group; torsion 3 h / detorsion 3 h + silymarin (250 mg/kg) group; and torsion 3 h / detorsion 24 h + silymarin (250 mg/kg) group. In the study, 720° torsion was applied to the left testicle.
10p
dolomite36
30-12-2021
13
0
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Tendon diseases and injuries are a serious problem for the aged population, often leading to pain, disability and a significant decline in quality of life. The purpose of this study was to determine the influence of aging on biochemistry and histology during tendon healing and to provide a new strategy for improving tendon healing.
10p
vimackenziebezos
30-11-2021
8
1
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Elevations in serum creatinine, uric acid, sodium, and potassium were reported in aged rats. Treatment with Ta-65 or pomegranate effectively ameliorated all the deteriorations induced by normal aging in male fertility and renal function. Ta-65 and pomegranate possessed strong antiaging activity by alleviating aging-induced male infertility through reestablishing the hormonal balance and testis architecture. They also alleviated the kidney dysfunction.
10p
thiencuuchu
27-11-2021
9
1
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Những Kim Tự Tháp Ai Cập vẫn luôn là một nghi vấn lớn đối với nhân loại. Có rất nhiều những câu hỏi đã được đặt ra, chẳng hạn: Ai đã xây dựng các Kim Tự Tháp? Họ xây dựng Kim Tự Tháp bằng cách nào? Và để làm gì? Nhưng không ai có thể trả lời chúng. Tuy nhiên, cuốn sách Năng lượng Kim Tự Tháp thời đại mới (The new age of Pyramiden ergy) này sẽ tiết lộ một phần nào đó cho người đọc những hiểu biết về Kim Tự Tháp từ các bậc thầy thiền định. Nguồn gốc, mục đích, và nguồn năng lượng phi thường kỳ diệu ẩn tàng trong những Kim Tự Tháp.
70p
lovebychance03
13-05-2021
22
1
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The effect of aged garlic extract on different haematological parameters was studied. The study included 72 Wistar albino rats were divided into 12 rats in each group. Group I served as normal control group. To group II high fat diet control was given as diet control. Rats in the group III were administered aged garlic extract at 200mg/kg bw. Group IV rats were administered aged garlic extract at 200mg/kg.bw with high fat diet. Rats in group V were administered atorvastatin at15mg/kg.bw with high fat diet.
10p
chauchaungayxua10
19-03-2021
17
1
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The study was conducted on weaned wistar male rats for the period of 8 weeks from 4 to 12 weeks of age and they were divided into 3 groups as control: rats fed diet without zinc supplementation, Treatment groups, T1 and T2: rats fed diet containing zinc sulphate @ 50mg and 100mg/kg body weight/day, respectively.
7p
chauchaungayxua10
19-03-2021
8
1
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Bone structure and strength are rapidly lost during conditions of decreased mechanical loading, and aged bones have a diminished ability to adapt to increased mechanical loading. This is a concern for older patients that experience periods of limited mobility or bed rest, but the acute effects of disuse on the bones of aged patients have not been thoroughly described.
11p
vitennessee2711
01-02-2021
17
2
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Knee osteoarthritis (KOA) is a degenerative knee disease commonly found in the ageing population. DNA methylation works with histone acetylation to participate in aging. Alterations of DNA methylation may involve the joint chondrocyte degeneration in KOA.
9p
vitennessee2711
02-02-2021
11
2
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Osteoarthritis (OA) is a common joint disease in aging societies, which is accompanied by chronic inflammation and degeneration of the joint structure. Inflammation of the infrapatellar fat pad (IFP) and synovial membrane (IFP surface) plays essential roles in persistent pain development in patients with OA.
10p
vivermont2711
28-01-2021
8
1
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Chronic inflammation with aging contributes to sarcopenia. Previous studies have suggested that the accumulation of adipose tissue in skeletal muscle, referred to as intermuscular adipose tissue (IMAT), increases with age and is associated with inflammation.
7p
vivermont2711
28-01-2021
7
1
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Three white female rats age approximately one year were presented with history of gradually increased swelling on thoracic region on left side and right side while other rat had mass on right side of neck. On the basis of history, clinical and ultrasonographic examinations diagnosed as a tumour and treated surgically under general anaesthesia. The histopathological examinations revealed fibroedinoma of mammary gland in two rats and a fibroma. All rats were recovered well without any complications.
4p
trinhthamhodang9
16-12-2020
10
1
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The study was undertaken for 150 days on female Sprague-Dawley rats to evaluate antioxidant effects on DMBA induced mammary tumours. A total of 80 rats were randomly allotted to 5 groups with 18 rats in 4 groups and 12 rats to the control group distributed to DMBA, DMBA + Tamoxifen and DMBA + Idivallathi mezhugu (IM) and IM groups. Rats were administered with 4 weekly doses of 5 mg DMBA/rat in olive oil by oral gavage beginning at 42nd day of age.
5p
kethamoi7
26-08-2020
5
1
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