Albino wistar rats

In view of the toxic effects of theobromine and the medicinal potentials of Vernonia amygdalina, the present study therefore evaluated the effect of ethanol leaf extract of Vernonia amygdalina on the heart, liver and kidney of theobromine intoxicated male albino rats.

9p viisac 23-09-2023 4 1   Download

The renal function plays a leading role in long-term control of arterial pressure. The comparative analysis of renal cortex transcriptome in ISIAH rats with inherited stress-induced arterial hypertension and normotensive WAG rats was performed using RNA-Seq approach.

14p vinarcissa 21-03-2023 5 1   Download

It has been demonstrated that administration of exogenous ketone supplement ketone salt (KS) and ketone ester (KE) increased blood ketone level and delayed the onset of isoflurane-induced anesthesia in different rodent models, such as Wistar Albino Glaxo Rijswijk (WAG/Rij) rats. The modulatory effect of adenosinergic system may have a role in the ketone supplementation-evoked effects on isoflurane-generated anesthesia.

11p vizhangzhidong 29-12-2021 5 0   Download

In this study, protective effects of lithium borate (LTB) on spermatogenesis as well as histopathological and immunohistochemical findings of testes in experimentally induced acute Cadmium (Cd) toxicity in rats were determined. Twenty-eight male Wistar albino rats, were used, weighing 200–220 g. Rats were randomly divided into 4 groups: Control, Cd, LTB, and LTB + Cd. Rats were anesthetized with ketamine at the end of the sixth day, blood was taken from their hearts, and the rats were decapitated. Typically, the control and LTB groups exhibited similar values.

11p dolomite36 30-12-2021 9 0   Download

The aim of the present study was to clarify the effects of silymarin on experimental testicular ischemia / reperfusion injury. A total of 40 Wistar albino rats (10–12 weeks of age, weighing 280–300 g) were randomly divided into five groups. Control group: No surgical procedures were performed. Torsion 3 h / detorsion 3 h group; torsion 3 h / detorsion 24 h group; torsion 3 h / detorsion 3 h + silymarin (250 mg/kg) group; and torsion 3 h / detorsion 24 h + silymarin (250 mg/kg) group. In the study, 720° torsion was applied to the left testicle.

10p dolomite36 30-12-2021 13 0   Download

Anti-oxidative stress characters of extract was evaluated in liver and kidney antioxidant enzyme activities; catalase, superoxide dismutase, glutathione reductase, glutathione-S-transferase and glutathione peroxidase which were magnified in parallel with remarkable elevation on glutathione concentration comparable with diabetic control.

13p schindler 30-12-2021 9 0   Download

N-acetylcysteine amide (NACA) is a new antioxidant molecule with powerful radical scavenging properties. The aim of this study was to investigate neuroprotective effects of NACA against paraquat (PQ) toxicity in the midbrains of rats by using motor coordination tests and biochemical and histological analysis. Thirty adult Wistar albino rats were divided into three groups: Group 1: control (n = 10), Group 2: PQ (10 mg/kg) (n = 10), and Group 3: PQ (10 mg/kg) + NACA (100 mg/kg) (n = 10). NACA was administrated intraperitoneally 30 min before PQ injection.

11p tudichquannguyet 29-11-2021 6 1   Download

The medicinal plants combine three properties – curative, preventive and nutritive which provide the human body with necessary strength and vigour to cope with the disease and facilitate the action of the curative agents in the herbal drug. The major prevalent killers of India are cancer, diabetes, heart and liver diseases (Debnath et al., 2015).

290p spiritedaway36 26-11-2021 10 2   Download

The effect of aged garlic extract on different haematological parameters was studied. The study included 72 Wistar albino rats were divided into 12 rats in each group. Group I served as normal control group. To group II high fat diet control was given as diet control. Rats in the group III were administered aged garlic extract at 200mg/kg bw. Group IV rats were administered aged garlic extract at 200mg/kg.bw with high fat diet. Rats in group V were administered atorvastatin at15mg/kg.bw with high fat diet.

10p chauchaungayxua10 19-03-2021 17 1   Download

The present study was designed to evaluate the role of umbelliferone in alleviating hyperlipidemia and oxidative damage in streptozotocin induced diabetes mellitus in wistar albino rats. Six groups of rats were used as control, diabetic control, umbelliferone at 20 mg/kg b.wt., umbelliferone at 40 mg/kg b.wt. and combination of glibenclamide and umbelliferone at 20 mg/kg b. wt., was used in the study.

13p trinhthamhodang1216 19-11-2020 12 0   Download

Hence the objective of this study was to assess the reproductive toxicity in male albino Wistar rats induced by doxorubicin and ameliorative effect of quercetin to overcome the doxorubicin induced testicular toxicity.

12p nguaconbaynhay8 13-10-2020 8 2   Download

Cisplatin (CP) is considered one of the most effective and widely used anti-neoplastic drug in the treatment of different solid organ tumors. The present study was carried out to assess the hematological changes following CP administration in Wistar albino rats and its amelioration by extract of Andrographis paniculata (AP). The study included 60 Wistar albino rats were divided into 12 rats in each group. Group I served as normal control group.

8p angicungduoc6 22-07-2020 8 1   Download

Fomesafen is widely used as herbicide for weed control. Fomesafen have both foliar and soil activity. It mostly control broadleaves. Fomesafen is labeled for postemergence applications to soybeans, peanuts, and rice. Although bronzing or burning of soybean leaf tissue is evident after application, yield is rarely affected. The present study was designed to evaluate the effect of repeated exposure of Fomesafen (Herbicide) by oral gavage method on the blood biochemistry of female wistar rats.

9p kethamoi6 29-06-2020 17 1   Download

This study evaluates the anti-cancer effects of Tadalafil (potent PDE-5 inhibitor) in female albino wistar rats against n-methyl n-nitrosourea induced mammary gland carcinogenesis.

15p vikuala271 13-06-2020 11 2   Download

Tartrazine (Yellow 5 or E102) is a synthetic food dye able to modify perception and behavior, causing agitation, confusion, rhinitis and can produce hyperactivity syndrome in children when is combined with benzoates.

11p vijiraiya2711 27-05-2020 9 1   Download

This study was aimed at investigating the effect of crude oil contaminated feeds on selected serum enzymes and electrolyte levels in Albino wistar rats. Albino wistar rats weighing between 180g to 200g were obtained from Ladoke Akintola University of Technology Ogbomosho, OyoState and used for the study. The animals were grouped into five study groups with six (6) animals in each group. The animals were kept in a wellventilated room comprising control group, crude oil group, garlic treated group, Vitamin C treated group and Vitamin E treated group.

11p cothumenhmong5 17-05-2020 5 1   Download

This study investigated the anti-diabetic effect of ethanolic bark extract of Khaya senegalensis in Alloxan-induced diabetic albino Wistar rats. Sixty (60) female albino rats were randomly placed into six (6) study groups of ten (10) animals designated as; nondiabetic control (NDC), diabetic control (DC), and diabetic extract treated groups (DSB1, DSB2, and DSB3) receiving varying extract concentration of 100mg/kg, 200mg/kg, and 400mg/kg body weight respectively.

17p cothumenhmong5 17-05-2020 8 1   Download

This study investigates the effect of ethanol root and leaf extracts of Sida acuta on some kidney function indices and electrolytes in albino wistar rats. The rats were divided into 4 groups of 7 rats each. Group 1 was the control group, group II received an oral dose of 100 mg/kg leaf extract of Sida acuta daily, group III received an oral dose of 100 mg/kg root extract of Sida acuta daily while group IV received 50 mg/kg each of leaf extract and root extract of Sida acuta daily.

8p kethamoi4 16-04-2020 6 1   Download

This study was conducted to evaluate the effects of ethanol seed extract of Cola lepidota (Monkey kola) on lipid profile and haematological parameters of albino wistar rats. Twenty eight (28) adult albino wistar rats weighing between 170g-200g were randomly divided into four groups of 7 rats each. The control group (I) was fed with normal rat chow ad libitum. Group II received daily oral dose of 100mg/kg of the extract, Group III received daily oral dose of 200mg/kg of extract while Group IV received daily oral dose of 300mg/kg.

9p trinhthamhodang1212 06-04-2020 12 1   Download

The present study was conducted to evaluate the hepatoprotective effect of the Hydroethanolic extract of the stem bark Oroxylum indicum against CCl4 induced hepatotoxicity. The hydroethanolic extract was prepared. Albino Wistar rats were taken for the study. The extract was prepared at a dose rate of 100mg/kg body weight, 300mg/kg body weight, 900mg/kg body weight. Carbon tetrachloride was used to induce hepatotoxicity.

7p caygaocaolon4 01-04-2020 18 1   Download