Alternative end joining
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Genome editing of malaria parasites is key to the generation of live attenuated parasites used in experimental vaccination approaches. DNA repair in Plasmodium generally occurs only through homologous recombination. This has been used to generate transgenic parasites that lack one to three genes, leading to developmental arrest in the liver and allowing the host to launch a protective immune response.
18p viaristotle 29-01-2022 11 0 Download
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The House Labor, HHS, Education Subcommittee recently recommended significantly reduced funding for CPB of $333.75 million for FY 2013. Following this, bipartisan support for public media in the Congress emerged, with six Republican Members of the House joining 111 Democratic Members, and two Republican Senators joining 36 Democratic Senators as signers of a “Dear Colleague” letter supporting continued funding of CPB.
21p mebachano 01-02-2013 27 2 Download