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Animal trials
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Part 2 book "Animal cruelty investigations - A collaborative approach from victim to Verdict™" includes contents: Search warrants and seizures, evidence collection, veterinary forensic necropsy, report writing, protective custody (live animals), media and fundraising, forfeiture, surrender, and related legal remedies, trial.
354p
dianmotminh01
14-05-2024
2
0
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Part 2 book "Updates on brucellosis" includes content: Blood cultures for the diagnosis of human brucellosis, antibiotic susceptibility testing of brucella species - old and new drugs, recombinant proteins as antigens in serological diagnosis of brucellosis, treatment of brucellosis, treatment of human brucellosis — review of evidence from clinical trials, control of animal brucellosis — the most effective tool to prevent human brucellosis.
144p
oursky09
08-11-2023
4
2
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Part 1 book "No way to treat a friend - Lifting the lid on complementary and alternative veterinary medicine" includes content: What is complementary and alternative veterinary medicine; why CAVM appears to work in animals; what is science and why does it matter; when thinking goes wrong, but we just know it works.
143p
oursky09
12-11-2023
3
2
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Continued part 1, part 2 of ebook "Veterinary epidemiology (Third edition)" provides readers with content including: clinical trials; diagnostic testing; comparative epidemiology; the economics of animal disease; health schemes; the control and eradication of disease; glossary of terms; basic mathematical notation and terms; some computer software; veterinary epidemiology on the internet; multipliers used in the construction of confidence intervals based on the normal distribution, for selected levels of confidence;...
323p
lytamnguyet
04-08-2023
5
2
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This Master by Research project aims to develop the human gas capsule that enables realtime intestinal gas profiling in a low-cost, non-invasive and accurate manner. The safety, viability, reliability and repeatability of the capsule will be evaluated in both laboratorial environments and animal trials that are influenced by dietary effect, heat-stress-induced gut disorder and dietary supplemental therapeutic agent.
104p
runthenight04
02-02-2023
4
1
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Cardiopulmonary bypass-related myocardial ischemia-reperfusion injury is a major contributor to post‑ operative morbidity. Although transcutaneous electrical nerve stimulation (TENS) has been found to have cardiopro‑ tective effects in animal studies and healthy volunteers, its effects on cardiac surgery under cardiopulmonary bypass patients have not been evaluated.
11p
viisaacnewton
26-04-2022
10
1
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Org 25435 is a new water-soluble alpha-amino acid ester intravenous anaesthetic which proved satisfactory in animal studies. This study aimed to assess the safety, tolerability and efficacy of Org 25435 and to obtain preliminary pharmacodynamic and pharmacokinetic data.
11p
viisaacnewton
26-04-2022
11
1
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Bovine respiratory disease (BRD) continues to be great challenge in calf rearing units. The urgent need to decrease the use of antibiotics and increase animal welfare in beef production has forced us to introduce new preventive methods. Vaccinations could contribute to the solution, but the high incidence of BRD already at an early age has made it difficult to introduce suitable vaccination programs.
10p
vigalileogalilei
28-02-2022
5
1
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Acupuncture has been used as a treatment for pain associated with osteoarthritis (OA) for thousands of years; however, there is a lack of definitive evidence for this indication in humans or animals. The aim of this study was to prospectively evaluate the efficacy of acupuncture on lameness and clinical function in dogs affected by naturally-occurring OA using objective outcome measures.
11p
vigandhi
23-02-2022
9
1
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Large-scale phenotype data can enhance the power of genomic prediction in plant and animal breeding, as well as human genetics. However, the statistical foundation of multi-trait genomic prediction is based on the multivariate linear mixed effect model, a tool notorious for its fragility when applied to more than a handful of traits.
25p
viarchimedes
26-01-2022
10
0
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The significant development in the construction of microscale cell culture platforms and the interest in bioanalytical analysis have recently resulted in the emergence of a new concept of ‘organ-on-a-chip’ systems. Organon-a-chip is a new three-dimensional (3D) in vitro microfabricated unit that contains a multichannel microfluidic cell culture. Even if many informative and useful data are obtained from animal models and in vitro assays, they are still limited for extrapolation to human systems during drug design and development.
24p
tudichquannguyet
29-11-2021
6
1
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Mutant peptides presented by MHC (major histocompatibility complex) Class II in cancer are important targets for cancer immunotherapy. Both animal studies and clinical trials in cancer patients showed that CD4 T cells specific to tumor-derived mutant peptides are essential for the efficacy of immune checkpoint blockade therapy by PD1 antibody.
9p
vitzuyu2711
29-09-2021
10
1
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Mechanical ventilation (MV) is the primary form of support for acute respiratory distress syndrome (ARDS) patients. However, intra- and inter-patient-variability reduce the efficacy of general protocols. Model-based approaches to guide MV can be patient-specific.
10p
vianthony2711
16-04-2021
4
2
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Idiopathic pulmonary fibrosis (IPF) is a severe and progressive respiratory disease with poor prognosis. Despite the positive outcomes from recent clinical trials, there is still no cure for this disease. Pre-clinical animal models are currently largely limited to small animals which have a number of shortcomings.
15p
vimontana2711
05-04-2021
13
3
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There is a need for agents that suppress inflammation and progression of chronic obstructive pulmonary disease. p38 mitogen-activated protein kinase (p38 MAPK) has been associated with this disorder, and several inhibitors of this cascade are in clinical trials for its treatment, but their efficacy and utility are unknown.
14p
vimontana2711
05-04-2021
9
2
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Mesenchymal stromal cells (MSC) have shown promising results in the treatment of tendinopathy in equine medicine, making this therapeutic approach seem favorable for translation to human medicine. Having demonstrated that MSC engraft within the tendon lesions after local injection in an equine model, we hypothesized that they would improve tendon healing superior to serum injection alone.
14p
vitennessee2711
01-02-2021
11
2
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Hepatocellular carcinoma (HCC) is one of the leading causes of cancer mortality in the world. Therefore, more and more studies are developing novel therapies to treat this disease. The pre-clinical trials on animals are a vital step to evaluate the efficacy as well as side effects of these novel therapies. Hence, this study aimed to develop the murine model of HCC using 3 kinds of mice: NOD/SCID, nude and Balb/c mice.
7p
larachdumlanat127
02-01-2021
12
2
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Malignant pleural effusions (MPE) are a common and fatal complication in cancers including lung or breast cancers, or malignant pleural mesothelioma (MPM). MPE animal models and immunotherapy trials in MPM patients previously suggested defects of the cellular immunity in MPE.
9p
vijennie2711
29-09-2020
12
0
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This disease is more prevalent in winter months mostly in the rice growing parts of India. Mostly younger buffaloes are more frequently affected than cattle. The disease cause general malaise, edema of the extremities, general wasting with necrosis and sloughing of the epidermis. The possibilities of mycotoxins produced from the wheat straw, dry grass or sorghum hay might be the one of the reason for this condition. The condition is usually a febrile and limits the movements of the affected animals due to painful condition of the legs.
3p
trinhthamhodang7
31-08-2020
18
2
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An On Farm Trial was conducted to evaluate the effect of shatavari (Asparagus recemosus) on milk production in lactating buffaloes which were parturated 1 to 4 months before commencement of trial. Total 20 lactating buffaloes were selected and fed 50 gm powder of shatavari roots in concentrates once in a day for a period of 180 days. The milk production was increased 0.60+ 0.27 kg (9.67%) daily respectively as compared to their previous production. Increase in the income by feeding shatavari came to Rs. 12.00/day/animal and B:C ratio was found 1:2.28.
3p
kethamoi5
03-06-2020
7
0
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