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Antagonistic activity
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Part 1 book "Basic and clinical pharmacology" includes contents: Introduction - The nature of drugs and drug development and regulation, drug receptors and pharmacodynamics, pharmacokinetics and pharmacodynamics - rational dosing and the time course of drug action, drug biotransformation, pharmacogenomics, introduction to autonomic pharmacology; cholinoceptor activating and cholinesterase inhibiting drugs; cholinoceptor blocking drugs; adrenoceptor agonists and sympathomimetic drugs, adrenoceptor antagonist drugs,... and other contents.
502p
dianmotminh01
17-05-2024
3
3
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Study on the antagonistic activity against two pathogenic bacteria in humans (Staphylococcus aureus and Streptococcus pneumoniae) of the Streptomyces MIP_L26 (Called MIP_L26), isolated from the soil in the root zone of the May Chang tree; to investigate the biological characteristics of MIP_L26.
6p
viohoyo
02-04-2024
3
2
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Ebook "Food emulsifiers and their applications (Second edition)" has focused on the design and application of emulsifiers as versatile food ingredients. The second edition has updated and expanded applications, from both theoretical and practical perspectives. The first three chapters describe design, synthesis, analysis, and commercial preparation of emulsifiers. Synergistic and antagonistic interactions with other food ingredients, such as carbohydrates, proteins, and water, are discussed in the next three chapters.
433p
manmanthanhla0201
27-02-2024
2
1
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B-cell lymphoma 2 (Bcl-2) family proteins are key regulators of apoptosis, which possess four conserved Bcl-2 homologies (BH) domains. Among the BH domains, the BH3 domain is considered as a potent ‘death domain’ while the BH4 domain is required for anti-apoptotic activity.
18p
visharma
20-10-2023
3
2
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Aprepitant inhibits the development and metastasis of gallbladder cancer via ROS and MAPK activation
Aprepitant, as a neurokinin-1 receptor (NK-1R) antagonist, originally applied for curing chemotherapyinduced nausea and vomiting, has been reported to have significant antitumor effect on several malignant tumors.
14p
visharma
20-10-2023
8
2
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In this study, we isolated rice endophytic bacteria and selected strains that have antagonistic activity against Dz for application in controlling the foot rot disease. The endophytic strain VY81 isolated from stem of a rice plant with foot rot disease was studied in details since it had prominent antagonistic activity against Dz.
9p
vimulcahy
18-09-2023
6
3
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Within the domain of neurorehabilitation, the scientific community has increasingly advocated for the employment of robotic apparatuses to facilitate prolonged and intensive motor therapy. Of particular importance is the frequently neglected hand and wrist rehabilitation, which is instrumental in regaining the fundamental abilities required for daily activities.
7p
viisac
15-09-2023
9
5
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Biocontrol of stem end disease agent, Alternaria alternata YZU, on pitaya is more interested in altering the application of chemical pesticides. This study was conducted to characterize antagonistic phosphate solubilizing bacteria (PSB) from rhizosphere soil for their biocontrol activities against A. alternata YZU under laboratory and greenhouse conditions.
8p
viberkshire
09-08-2023
10
4
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Stem end rot is the most destructive disease caused by Alternaria alternata YZU in pitayagrowing regions of Vietnam. This study was conducted to characterize antagonistic phosphatesolubilizing bacteria (PSB) from rhizosphere soil for their biocontrol activities against A. alternata YZU and evaluate the effect of temperature, pH, and water activity on that antagonism.
8p
vispiderman
15-06-2023
9
1
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Pathogenic Escherichia coli (E. coli) is an important causative agent for infectious diseases in pigs and causes significant economic loss. The global concern of antimicrobial resistance of bacteria raises awareness of the alternative ways of using antimicrobial peptides (AMPs).
13p
vidarwin
22-02-2022
4
1
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In vitro analyzing the antagonistic activity of seventy native bacterial isolates towards plant tumorigenic Agrobacterium tumefaciens resulted in a selection of eight potential biocontrol agents. These isolates were screened for their antagonistic effect in vitro as well as their efficacy in reducing gall formation in planta.
7p
schindler
30-12-2021
9
0
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These isolates were screened, in vitro, according to their capacities to produce plant growth promoting substance i.e. IAA, phosphate, potassium solubilization, chitinase activities and hydrogen cyanide. Results indicated that 36 bacterial isolates showed IAA production, 25 HCN production, 57 chitinase activities, 39 phosphate and 105 potassium solubilizers.
8p
schindler
30-12-2021
9
0
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This study aimed to investigate the antagonistic effect of three strains of the genus Bacillus on toxigenic fungi contaminating food commodities, with emphasis on two ochratoxigenic isolates (A. ochraceus, A. westerdijkiae) and two aflatoxigenic isolates (A. flavus and A. parasiticus). In vitro studies were carried out using two different methods for cultivation tested bacilli with fungal isolates – coincubation and dual culture method.
7p
mudbound
10-12-2021
8
1
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In this study, we performed the pharmacophore modeling and 4D-QSAR research of alkynylphenoxyacetic acid analogues as CRTh2 receptor opponent agents by utilizing the electron conformational genetic algorithm method. Quantum chemical calculations and conformational analyses of the compounds were carried out at HF/6-31G* level. Then electron conformational matrices of congruity were prepared for each conformer of each compound, which are represented by electronic and structural properties.
21p
tudichquannguyet
29-11-2021
10
0
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In clear cell renal cell carcinoma, 80% of cases have biallelic inactivation of the VHL gene, leading to constitutive activation of both HIF1α and HIF2α. As HIF2α is the driver of the disease promoting tumour growth and metastasis, drugs targeting HIF2α have been developed. However, resistance is common, therefore new therapies are needed.
12p
vimahuateng
26-11-2021
8
1
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Epigenetic modifications including DNA methylation and post-translational modifications of histones are known to regulate gene expression. Antagonistic activities of histone acetyltransferases (HATs) and histone deacetylases (HDACs) mediate transcriptional reprogramming during insect development as shown in Drosophila melanogaster and other insects.
15p
viseulgi2711
31-08-2021
11
1
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Wilt caused by Fusarium oxysporum f. sp. ricini poses a major problem in all the castor growing areas of the country. Since the soil borne disease can be effectively controlled by biocontrol agents, the present study was conducted to know the antagonistic activity of different bioagents in vitro at department of Plant Pathology, College of Agriculture, UAS, GKVK, Bengaluru during 2019-20.
8p
caygaocaolon11
21-04-2021
19
1
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The tissue factor (TF)-dependent extrinsic pathway has been suggested to be a central mechanism by which the coagulation cascade is locally activated in the lungs of patients with acute lung injury and acute respiratory distress syndrome (ALI/ARDS) and thus represents an attractive target for therapeutic intervention.
8p
vianthony2711
16-04-2021
12
2
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Epithelial-mesenchymal transition (EMT) has been proposed as a mechanism in the progression of airway diseases and cancer. Here, we explored the role of acetylcholine (ACh) and the pathway involved in the process of EMT, as well as the effects of mAChRs antagonist.
11p
vimontana2711
05-04-2021
9
1
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This study evaluated the effects of aclidinium bromide, a long-acting muscarinic antagonist indicated for maintenance treatment of chronic obstructive pulmonary disease (COPD), on exercise endurance, dyspnea, lung hyperinflation, and physical activity.
12p
vimontana2711
05-04-2021
10
1
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