Anti-hypertensive drugs

Previously studies shown a potential risk of antihypertensive medicines in relation to cancer susceptibility, which creating significant debate in the scientific community and public concern. We sought to investigate the relationship between antihypertensive medicines and cancer risk, by drug type and class.

10p visharma 20-10-2023 4 2   Download

Drug therapy to achieve the recommended target blood pressure remains the cornerstone of the management of hypertension. Today, there are strong evidences from randomized controlled trials that antihypertensive drugs are more effective than placebo at reducing cardiovascular mortality and morbidity.

8p vicaptainmarvel 21-04-2023 3 2   Download

A simple, stable, and specific high-performance liquid chromatography coupled with a DAD detector (HPLC-DAD) method has been developed and validated for the simultaneous determination of amlodipine, felodipine, furosemide, nifedipine, and spironolactone in traditional herbal products. The analytes were extracted in acetonitrile: water (50 : 50, v/v) with help of the ultrasonic. The separation of analytes was performed in an Apollo C18 column (250 × 4.6 mm; 5 µm) and a mobile phase consisting of mixture acetonitrile: 0.1% phosphoric acid in gradient elution.

10p chauchaungayxua12 11-07-2021 13 2   Download

To investigate the effects of coadministration of esaxerenone with amlodipine on the pharmacokinetics (PK) of each drug, and of esaxerenone on the PK of digoxin.

10p vidhaka2711 31-07-2020 51 3   Download

Changes in antihypertensive drug treatment are paramount in the adequate management of patients with hypertension, still, there is little information regarding changes in antihypertensive drug treatment in Switzerland. Our aim was to assess those changes and associated factors in a population-based, prospective study

9p vienzym2711 03-04-2020 8 1   Download

Clonidine is an imidazoline sympatholytic, acting on both α2-adrenergic and imidazoline receptors in the brainstem to induce antihypertensive and negative chronotropic effects in the vasculature and heart respectively.

4p vimax2711 30-03-2020 11 2   Download

Although the pathophysiological mechanisms of arterial hypertension are different in obese and lean patients, hypertension guidelines do not include specific recommendations for obesity-related hypertension and, therefore, there is a considerable uncertainty on which antihypertensive drugs should be used in this condition.

8p vienzym2711 30-03-2020 11 1   Download

Adherence to prescribed medication is an imperative issue which can be directly linked with the management of chronic diseases like hypertension; failure to adhere can affect the effectiveness of medication as well as the efficiency of the health care system.

10p vimax2711 30-03-2020 9 2   Download

Metolazone is a diuretic, saluretic and antihypertensive chemical compound from the quinazoline category that possesses medicinal features similar to those of other thiazide diuretic drugs. However, the pharmacokinetics of metolazone in the Chinese population has rarely been studied.

10p vimax2711 30-03-2020 30 2   Download

The present investigation focused on the development of Diltiazem HCl (DTH) matrix film and its characterization by in-vitro, ex-vivo and in-vivo methods. Films were prepared by solvent casting method by taking different ratios of hydroxypropyl methylcellulose K4M (HPMC K4M) and Eudragit RS100.

12p kequaidan1 16-11-2019 22 0   Download

Angiotensin-converting enzyme (ACE) plays a central role in blood pressure regulation by producing the vasoconstrictor angiotensin II. The inhibition of ACE with natural inhibitors, as alternatives to avoid the side effect of synthetic drugs, is a major target in the prevention of hypertension. In this study, we examined the separated caseins and whey proteins of goat milk for the presence of ACE inhibitory peptides.

9p kequaidan1 16-11-2019 19 1   Download

part 1 book “basic & clinical pharmacology” has contents: drug biotransformation, agents used in cardiac arrhythmias, diuretic agents, antihypertensive agents, vasoactive peptides, cholinoceptor-blocking drug, drugs used in asthma, antiseizure drugs,… and other contents.

604p tieu_vu13 06-08-2018 51 2   Download

(bq) part 1 book "pediatric drug doses" presents the following contents: analgesics, antiasthmatics, antiarrhythmics, antibiotics, anticoagulants, antidotes poisoning, antiemetics, antiepileptics, antifungals, antihypertensives,...

130p thangnamvoiva6 19-07-2016 60 3   Download

The increasing awareness of the importance of chirality in the context of biological activity has stimulated a growing demand for efficient methods for industrial synthesis of pure enantiomers including chiral antiinflammatory drugs such as naproxen (Xin et al., 2001) and ibuprofen (Lee et al., 1995; Ducret et al., 1998; Xie et al., 1998; Arroyo et al., 1999; Chen and Tsai, 2000); antihypertensive agents such as angiotensin-converting enzyme (ACE) inhibitors (e.g., captopril, enalapril, ceranopril, zofenapril, and lisinopril); and the calcium channel- blocking drugs such as diltiazem.

109p loixinloi 08-05-2013 53 4   Download

Hypertension and Chronic Kidney Disease: Cause and Consequence – Therapeutic Considerations 45 Elsa Morgado and Pedro Leão Neves Potassium-Sparing Diuretics in Hypertension 67 Cristiana Catena, GianLuca Colussi and Leonardo A. Sechi Hypertension and Renin-Angiotensin System Roberto de Barros Silva Pharmacokinetic Interactions of Antihypertensive Drugs with Citrus Juices 95 Yoshihiro Uesawa Drug Interaction

160p xumxaxumxit 13-04-2013 63 3   Download

Many of my friends have been anxious ever since Osteopathy became an established fact, that I should write a treatise on the science. But I was never convinced that the time was ripe for such a production, nor am I even now convinced that this is not a little premature. Osteopathy is only in its infancy, it is a great unknown sea just discovered, and as yet we are only acquainted with its shore-tide. When I saw others who had not more than skimmed the surface of the science, taking up the pen to write books on Osteopathy, and after having carefully examined their productions,...

119p hotmoingay9 02-02-2013 43 5   Download

With publication of the human genome has come an experiment in reductionism for drug discovery. With the evaluation of the number and quality of new drug treatments from this approach has come a reevaluation of target-based versus systems-based strategies. Pharmacology, historically rooted in systems-based approaches and designed to give systems-independent measures of drug activity, is suitably poised to be a major (if not the major) tool in this new environment of drug discovery.

294p mnemosyne75 02-02-2013 36 4   Download

Tham khảo sách 'modern pharmacology with clinical applications', y tế - sức khoẻ, y học thường thức phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả

811p mnemosyne75 02-02-2013 57 5   Download

Pharmacology has undergone major intellectual changes in the recent years and has become increasingly important to all medical, dental and other health professionals. The graduate students of dentistry may have to handle medical emergency during various dental procedures on the dental chair. Besides this, dentists have to look into various drug associated interactions. The broad goal of teaching pharmacology to undergraduate students is to inculcate rational and scientific basis of therapeutics keeping in view the dental curriculum and profession.

501p hyperion75 21-01-2013 62 7   Download

The sixth edition of Modern Pharmacology With Clinical Applications continues our commitment to enlisting experts in pharmacology to provide a textbook that is up-to-date and comprehensive. Designed to be used during a single semester, the book focuses on the clinical application of drugs within a context of the major principles of pharmacology. It is meant to serve students in medicine, osteopathy, dentistry, pharmacy, and advanced nursing, as well as undergraduate students.

811p gian_anh 18-10-2012 75 16   Download