Anti-inflammatory activity

Vetiver grass (Vetiveria zizanioides L.) is a perennial grass, native to India and now cultivated in many parts of the tropics. In this study, we examined the antiinflammatory activity of the ethanol extract from Vetiver roots through the albumin protein denaturation model.

6p visergeyne 18-06-2024 0 0   Download

Zoanthid is a potential natural resource with many biological activities, such as antioxidant, antiviral, antiinflammatory, and cytotoxic activity. Therefore, this study aimed to evaluate the antioxidant activity of 70% ethanol crude extract and dichloromethane fraction from Zoanthus vietnamensis. The total polyphenol content of ethanol and dichloromethane extracts were 19.36 ± 1.37 and 24.95 ± 0.63 mg GAE/g extract, respectively.

9p dianmotminh02 03-05-2024 4 1   Download

Flavonoids are a diverse group of natural compounds extensively studied in various research articles. They are widely distributed in the plant kingdom and exhibit various biological activities, including antioxidant, antiinflammatory, anticancer, antiviral, and antimicrobial effects. The genus Knema Lour., which contains many species in Southeast Asia, has been traditionally used to treat various ailments. The current review aims to provide a comprehensive update on the isolation of flavonoids and other secondary metabolites from the genus Knema Lour. between 1978 and 2022.

15p dianmotminh02 03-05-2024 5 2   Download

Bruguiera parviflora belongs to Bruguiera genus, which possesses several biological activities such as antidiabetic, antiinflammatory, and antioxidant. Phytochemical investigation of the ethyl acetate extract from Bruguiera parviflora leaves was carried out bioassay-guided isolation and obtained three known compounds, namely kochioside A (1), oleanolic acid (2) and quercitrin (3).

8p vibego 02-02-2024 1 0   Download

Ebook "Sesquiterpene lactones: Advances in their chemistry and biological aspects" addresses chemical and biological aspects related to sesquiterpene lactones (STLs). Experts in different fields have been invited to contribute on this class of compound's chemistry, isolation and identification, biological activities (antibacterial, antifungal, antiviral, antitrypanosomal, antileishmanial,antiplasmodial, antiproliferative and antiinflammatory), synthesis, biosynthesis, derivatization and QSAR analysis.

379p lamquandat 28-12-2023 7 2   Download

The Camellia tamdaoensis Hakoda et Ninh contains many useful phenolic compounds for human health, among them, flavonoids showed many biological activities such as antibacterial, antiinflammatory. In this study, we used the recovery extract method to collect concentrated solutions with high flavonoid content from golden tea leaves, in which ethanol served as solvents at the temperature of 70°C for 1 hour.

9p viberkshire 09-08-2023 6 2   Download

The medicinal plant Olax imbricata is well-known for its antioxidant, antiinflammatory, antibacterial, and diabetes-treating properties. It is essential to investigate the chemical composition and biological activity of Olax imbricata.

7p viwhitewolf 11-07-2023 3 2   Download

Onosma L., the largest genus of Boraginaceae, is represented by 105 species in Turkey with an endemism rate of 52%. Phytochemical studies indicate that Boraginaceae plants mainly comprise naphthoquinones with a wide range of biological activities including anticancer, antiinflammatory, wound healing, and antioxidant effects. However, few taxa of the genus Onosma have been investigated in detail for their bioactivities.

13p lyhuyenthu 31-01-2023 5 2   Download

Five naturalsecondary metabolites as cinnamic acid (1), (+)-catechin (2), (−)-epicatechin (3), p-coumaric acid (4), and ferulic acid (5) were isolated from Amanita caesarea based on antiinflammatory activity-guided extraction. Their structures (1−5) were determined by NMR spectra as well as by comparison with previously reported literature.

4p visirius 11-01-2023 5 2   Download

The role of recombinant activated protein C (aPC) during sepsis is still controversial. It showed antiinflammatory effect and improved the microvascular perfusion in experimental models of septic shock. The present study was aimed at testing the hypothesis that recombinant aPC therapy improves the microcirculation during severe sepsis.

8p viisaacnewton 26-04-2022 10 1   Download

Photodynamic therapy (PDT) applications enable light-controlled activation of drug candidates instead of their constitutive activities to prevent undesired side effects associated with their constant activities. A specific wavelength of light is utilized to enable electron mobility in the chemical structure, which results in differential activities that may alter cell viability and cellular functions. Canonical photodynamic therapy applications mostly focus on cytotoxicity-based antimicrobial and anticancer properties of the PDT agents.

9p langthannam 29-12-2021 9 0   Download

Nonsteroidal antiinflammatory drugs (NSAIDs) are widely used for the treatment of pain and inflammation. Some undesirable effects are linked with NSAIDs such as the gastrointestinal tract (GIT) toxicity and cardiovascular disturbances. At present the preparation of a hybrid molecular technique is being used to produce new analgesic and antiinflammatory molecules. Attachment of NSAIDs with nitric oxide and hydrogen sulfide releasing molecules produced some gastroprotective agents with improved analgesic and antiinflammatory activities.

20p tudichquannguyet 29-11-2021 7 1   Download

Voltammetric behaviors of six nitro-substituted benzamides, which are potential prodrug candidates for nitroreductase-based cancer therapy, were investigated using cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The electrochemical behavior of aromatic nitro (ArNO2) compounds by CV indicates that compounds involve various reduction/oxidation steps including the formation of aromatic nitro radical, nitroso, hydroxylamine, and amine groups.

19p tudichquannguyet 29-11-2021 4 1   Download

Ketoprofen and isoniazid together are a potential combination of a nonsteroidal antiinflammatory drug and an antitubercular medicine to treat tuberculosis and associated symptoms like fever and fatigue. The Schiff base of isoniazid with ketoprofen is synthesized in this research. Infrared spectroscopy (IR) and X-ray diffraction (XRD) analysis of the crystal packing proved the formation of the Schiff base and the existence of N-H···O hydrogen bonds between the hydrogen-bonded dimer of the Schiff base.

23p tudichquannguyet 29-11-2021 15 0   Download

A one-pot, environmentally friendly, and efficient protocol for the synthesis of novel polyfunctionalized benzo[a]pyrimido[5’,4’:5,6]pyrido[2,3-c ]phenazine derivatives has been reported by a one-pot, four-component sequential reaction between 2-hydroxynaphthalene-1,4-dione, benzene-1,2-diamines, benzaldehydes, and 6-amino-1,3-dimethyluracil in the presence of p-TSA as a nontoxic, inexpensive, ecofriendly, and efficacious solid acid catalyst. Two C-C bonds, two C=N bonds, and one C-N bond, as well as two new rings, were formed in this reaction.

10p tudichquannguyet 29-11-2021 19 1   Download

Pyrimidine derivatives are well known due to their remarkable pharmacological potential in various fields of science, and they are also present in some natural substances like DNA and RNA. These scaffolds manifest diversified biological activities such as antimicrobial, antiinflammatory, anti-HIV, antitubercular, antitumor, antineoplastic, and antimalarial. A pyrimidine ring is constructed when chalcones, amidines, guanidine, nitriles, isocyanates, urea, thiourea, and aminopyrazoles undergo condensation, coupling, or cyclization reactions.

38p tudichquannguyet 29-11-2021 11 1   Download

protect endangered tissueBenzoxazoles are DNA base bioisosteres and studies suggest that their derivatives have antiproliferative activities. Based on their antiproliferative activities they have been mostly studied as new generation anticancer drugs. In our study we exploited their antiproliferative effect, aiming to delineate bisbenzoxazole derivatives’ (RHE 231 and RHE 238) potential antiinflammatory effect on mouse macrophages that are activated in vitro through danger signal LPS stimulation. RAW 267.

15p tudichquannguyet 29-11-2021 10 1   Download

Teucrium species have been used in folk medicine as antidiabetic, antiinflammatory, antiulcer, and antibacterial agents. We have explored in vitro antidiabetic impacts of 2 natural diterpenoids, alysine A and alysine B, isolated from Teucrium alyssifolium.

23p tudichquannguyet 29-11-2021 4 0   Download

Isoquercitrin is a flavonoid chemical compound that can be extracted from different plant species such as Mangifera indica (mango), Rheum nobile, Annona squamosal, Camellia sinensis (tea), and coriander (Coriandrum sativum L.). It possesses various biological activities such as the prevention of thromboembolism and has anticancer, antiinflammatory, and antifatigue activities. Therefore, there is a critical need to elucidate and predict the qualitative and quantitative properties of this phytochemical compound using the high performance liquid chromatography (HPLC) technique.

13p tudichquannguyet 29-11-2021 12 1   Download

: This paper includes the result of the first study of the chemical composition, antioxidant, antiinflammatory, and antidiabetic activities of the essential oils of Glebionis coronaria (L.) Cass. ex Spach and Glebionis segetum (L.) Fourr. from Turkey. In the current study, nine and twenty-eight constituents were determined in the essential oils of aerial parts of G. coronaria (GCE) (92.1%) and G. segetum (GSE) (90.0%), respectively. The main components were capillin (65.9%) in GCE, capillene (53.4%) in GSE. The essential oil compositions were evaluated and compared with previous researches.

8p tudichquannguyet 29-11-2021 9 1   Download