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Antibody structure prediction
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Ebook "Hemorrhagic fever viruses: Methods and protocols" presents protocols that analyze and explore hemorrhagic fever viruses (HFV). This book is divided into 5 parts: Part I begins with an overview on predicting viral pandemics and then covers methods for surveillance, diagnosis, and classification of HFV. This includes an antibody capture method using Lassa virus antigens. Part II discusses structural studies and reverse genetics of HFV.
416p
lucchinguyen
28-12-2023
5
3
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Tralokinumab is an anti–interleukin (IL)-13 monoclonal antibody investigated for the treatment of severe, uncontrolled asthma in two Phase III clinical trials, STRATOS 1 and 2. The STRATOS 1 biomarker analysis plan was developed to identify biomarker(s) indicative of IL-13 activation likely to predict tralokinumab efficacy and define a population in which there was an enhanced treatment effect; this defined population was then tested in STRATOS 2.
17p
vimaine2711
26-03-2021
14
2
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The de novo design of a novel protein with a particular function remains a formidable challenge with only isolated and hard-to-repeat successes to date. Due to their many structurally conserved features, antibodies are a family of proteins amenable to predictable rational design.
13p
viwyoming2711
16-12-2020
16
1
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Recent efforts in HIV-1 vaccine design have focused on immunogens that evoke potent neutralizing antibody responses to a broad spectrum of viruses circulating worldwide. However, the development of effective vaccines will depend on the identification and characterization of the neutralizing antibodies and their epitopes.
15p
vikentucky2711
26-11-2020
13
1
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Computational methods provide approaches to identify epitopes in protein Ags to help characterizing potential biomarkers identified by high-throughput genomic or proteomic experiments. PEPOP version 1.0 was developed as an antigenic or immunogenic peptide prediction tool.
17p
vicolorado2711
23-10-2020
10
0
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Canine parvovirus is the major cause of haemorrhagic gastroenteritis in canines worldwide. There is a high morbidity and mortality in the young puppies. The currently available CPV vaccine is protecting from all antigenic strains but still there is vaccination failure as the strains are emerging at higher rate.
6p
angicungduoc6
22-07-2020
7
1
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Low molecular weight haptens (
14p
viuchiha2711
21-04-2020
10
0
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Edwardsiella tarda is a Gram negative bacterium with a wide host range, mainly affecting fishes. It is a dreaded pathogen of cat fish culture. The presence of large number of serotypes of the pathogen makes the vaccine production against the pathogen a difficult task. Here in this study the suitability of outer membrane protein W (OMP W) as a vaccine candidate against E. tarda was investigated.
12p
trinhthamhodang1212
06-04-2020
11
2
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