Antiepileptic drugs
-
A description of our current understanding of antiepileptic drug use during pregnancy, this book includes chapters on the impact of seizures on the mother and developing child, changes in maternal physiology during pregnancy and its impact on drug disposition, and the pharmacokinetic differences between the various anti-seizure medications.
235p vimeyers 29-05-2024 7 2 Download
-
Ebook Behavioural neurology of antiepileptic drugs: A practical guide - Part 2 includes content: Behavioural co-morbidities in epilepsy, antiepileptic drugs and behaviour - mechanisms of action; carbamazepine, oxcarbazepine, and eslicarbazepine; clonazepam and clobazam, ethosuximide, levetiracetam, piracetam, and brivaracetam,…and other contents. Invite you to consult the details.
87p longtimenosee03 01-02-2024 2 0 Download
-
Ebook Behavioural neurology of antiepileptic drugs: A practical guide - Part 2 includes content: Comparative evidence and clinical scenarios, phenobarbital and primidone, phenytoin, pregabalin, other antiepileptic drugs - rufinamide, lacosamide, perampanel,…and other contents. Invite you to consult the details.
85p longtimenosee03 01-02-2024 5 0 Download
-
Dyskinesia is a movement disorder categorized by involuntary movement of muscle. Although dyskinesia can be brought on by taking medications, it can also be a symptom of a variety of diseases. Antiepileptic druginduced involuntary movements have been well researched. Rare reports have been made for dyskinesia, a type of dystonia caused by phenytoin.
3p vitiki 30-01-2024 7 2 Download
-
Part 2 book "Rang and Dale's pharmacology" includes content: Chemical transmission and drug action in the central nervous system, amino acid transmitters, other transmitters and modulators, neurodegenerative diseases, general anaesthetic agents, analgesic drugs, local anaesthetics and other drugs affecting sodium channels, anxiolytic and hypnotic drugs, antiepileptic drugs, antipsychotic drugs, antidepressant drugs, psychoactive drugs, drug abuse and dependence
348p muasambanhan05 22-01-2024 4 2 Download
-
Epilepsy is a chronic non-communicable disease that can affect all ages, genders, races, and social classes with large treatment costs that vary widely between countries and regions. Perampanel is a new generation of antiepileptic drugs (AEDs), but cost-effectiveness reports are inconsistent in several countries that have conducted pharmacoeconomic evaluations.
9p vipriyankagandhi 27-07-2022 9 2 Download
-
The relationship between monogenic and polygenic forms of epilepsy is poorly understood and the extent to which the genetic and acquired epilepsies share common pathways is unclear. Here, we use an integrated systems-level analysis of brain gene expression data to identify molecular networks disrupted in epilepsy
18p vialfrednobel 29-01-2022 10 0 Download
-
Lamotrigine (LMT), chemically known as [6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine], is a broad spectrum antiepileptic drug, used as monotherapy and as an adjunct with other antiepileptic drugs for treatment of partial and generalized toxic-clonic seizures.
10p tocectocec 25-05-2020 16 0 Download
-
Cutaneous adverse reactions (CARs) from antiepileptic drugs (AEDs) are common, ranging from mild to life-threatening, including Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). The identification of subjects carrying the HLA-B*15:02, an inherited allelic variant of the HLAB gene, and the avoidance of carbamazepine (CBZ) therapy in these subjects are strongly associated with a decrease in the incidence of carbamazepine-induced SJS/TEN. In spite of the strong genetic associations, the initiation of hypersensitivity for AEDs is still not very well characterized.
10p caothientrangnguyen 09-05-2020 10 1 Download
-
Gender-based pharmacokinetics and/or pharmacodynamics differences can result in differences in treatment which can accordingly affect the drug safety and/or efficacy. A new validated bio-analytical LC-MS/ MS method was developed for the estimation of ezogabine, a third-generation antiepileptic drug, in human plasma using oxcarbazepine as an internal standard (IS) and to study the gender effect on the pharmacokinetic parameters in Egyptian human subjects.
6p partimesinhvien 08-05-2020 18 1 Download
-
This active, open observational study aimed to investigate adverse drug reactions (ADRs) associated with six commonly used antiepileptic drugs (AEDs) in southern Chinese outpatients with epilepsy from 2003 to 2015.
8p vimax2711 30-03-2020 7 1 Download
-
Sodium valproate is one of the most widely used antiepileptics and mood stabilizers. However, this drug may induce acute pancreatitis. Few cases have been reported so far, mainly on the pediatric patients who underwent antiepileptic treatment.
3p vimax2711 27-03-2020 14 0 Download
-
Despite the high prevalence of seizure, epilepsy and abnormal electroencephalograms in individuals with autism spectrum disorder (ASD), there is little information regarding the relative effectiveness of treatments for seizures in the ASD population.
18p virubber2711 21-03-2020 7 0 Download
-
This study investigated whether long-term treatment with antiepileptic drugs (AEDs) had negative effects on statural growth and serum calcium levels in children with epilepsy in Taiwan.
7p vinatri2711 29-02-2020 19 1 Download
-
Levetiracetam is a broad spectrum antiepileptic drug (AED) with proven efficacy when used as adjunctive therapy against myoclonic seizures. We report two patients suffering from epilepsy with myoclonic-astatic epilepsy (MAE) who experienced a paradoxical worsening of seizures after initiation of treatment with LEV, a finding not previously described.
4p vichengshin2711 26-02-2020 16 1 Download
-
Children with longstanding use of antiepileptic drugs (AEDs) are susceptible to developing low bone mineral density and an increased fracture risk. However, the literature regarding the effects of AEDs on growth in epileptic children is limited.
6p vichengna2711 25-02-2020 23 1 Download
-
Elevated rates of affective disturbance in children with benign childhood epilepsy with centrotemporal spikes (BCECTS) have been reported. However, it remains unclear how anxiety and depression are related to epilepsy, and it is unknown whether these mood disorders are influenced by the use of antiepileptic drugs.
6p videshiki2711 21-02-2020 32 1 Download
-
No guidelines exist concerning the maintenance antiepileptic drug to use after neonatal seizures. Practices vary from one hospital to another. The aim of this study was to investigate etiologies and to report on the use of maintenance antiepileptic therapy in our population of full-term neonates presenting neonatal seizures.
9p virome2711 13-01-2020 15 1 Download
-
Voltage-gated sodium channels (VGSCs) are drug targets for the treatment of epilepsy. Recently, a decreased risk of cancer associated with sodium channel-blocking antiepileptic drugs (AEDs) has become a research focus of interest.
12p viwashington2711 04-12-2019 6 1 Download
-
The long term use of antiepileptic drugs possesses many unwanted effects; thus, new safe combinations are urgently mandated. Hence, the present study aimed to investigate the anticonvulsant effect of kava alone or in combination with a synthetic anticonvulsant drug, diazepam (DZ). To this end, female Wistar rats were divided into two subsets, each comprising 6 groups as follows: group (i) received 1% Tween 80 p.o. and served as control, while groups (ii) and (iii) received kava at two dose levels (100 and 200 mg/kg, p.o.). The remaining three groups received (iv) DZ alone (10 mg/kg p.o.
8p kethamoi1 17-11-2019 17 1 Download