Antigenic mimicry

Chlamydia pneumoniae is a common cause of atypical community acquired pneumonia (CAP). The diagnostic approach of chlamydial infections remains a challenge. Diagnosis of delayed chlamydial-associated complications, involving complex autoimmune pathophysiological mechanisms, is still more challenging.

8p vimackenziebezos 29-11-2021 9 1   Download

Computational methods provide approaches to identify epitopes in protein Ags to help characterizing potential biomarkers identified by high-throughput genomic or proteomic experiments. PEPOP version 1.0 was developed as an antigenic or immunogenic peptide prediction tool.

17p vicolorado2711 23-10-2020 10 0   Download

In endemic area, nasopharyngeal carcinoma (NPC) tumor cells harbor EBV latent infection and expresses viral antigens such as EBNA1, LMP1 and LMP2. In this study, we established a NPC-mimicry animal model and assessed the therapeutic potential of LMP1 vaccine.

9p vimale2711 25-08-2020 17 1   Download

Trichuris ovis is one of the prevalent and non-pathogenic nematode of sheep. The whole anterior part of T. ovis remains embedded in the caecal mucosa of sheep with any marked inflammatory reaction. Helminth parasites evade host immune response by acquiring some host proteins or by mimicry of host antigens. The present study was conducted to explore any molecular mimicry between the T. ovis and sheep.

14p trinhthamhodang1213 29-05-2020 9 0   Download

Outer-Membrane Components Associated with Virulence Meningococcal strains are characterized by the expression of capsular polysaccharide and other outer-membrane structures, including LOS (endotoxin). Outer-membrane blebbing, meningococcal autolysis, molecular mimicry, genome plasticity, horizontal DNA exchange, and phase and/or antigenic variation are all important in meningococcal virulence. Capsule The polysaccharide capsule is a major—if not the major—virulence factor of N. meningitidis.

5p colgate_colgate 21-12-2010 74 2   Download