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Antiviral drugs
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This book contains information obtained from authentic and highly regarded sources. While all reasonable efforts have been made to publish reliable data and information, neither the author[s] nor the publisher can accept any legal responsibility or liability for any errors or omissions that may be made. The publishers wish to make clear that any views or opinions expressed in this book by individual editors, authors or contributors are personal to them and do not necessarily reflect the views/opinions of the publishers.
4894p
vimeyers
29-05-2024
4
1
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Part 3 book "Basic and clinical pharmacology" includes contents: Beta lactam and other cell wall and membrane active antibiotics; tetracyclines, macrolides, clindamycin, chloramphenicol, streptogramins and oxazolidinones; aminoglycosides and spectinomycin; sulfonamides, trimethoprim, & quinolones; antimycobacterial drugs; antifungal agents; antiviral agents; miscellaneous antimicrobial agents disinfectants, antiseptics and sterilants,... and other contents.
686p
dianmotminh01
17-05-2024
4
3
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In this study, two derivatives of hydrazineylidene-3-oxopropanal: chlorophenyl (CPHO) and Nitrophenyl (NPHO) substituted hydrazineylidene compounds were synthesized, spectroscopically characterized using (FT-IR, UV, and NMR), and theoretically modelled as a potential drug for the treatment of antiviral hepatitis (HBV and HCV) using insillico molecular docking approach.
17p
dianmotminh02
03-05-2024
3
1
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Ebook "Synthesis and characterization of glycosides (Second edition)" is a short and comprehensive study on the best known approaches for preparing the main types of glycosides. It covers synthetic pathways of challenging glycosides known as antiviral or antineoplastic drugs, and synthetic substrates used for enzymatic detection, including those used for detection of gene markers in plant biotechnology. The author pays special attention to the structural characterization of glycosides and provides the basic tools for the structural assignment through NMR, X-Ray and mass spectra techniques.
432p
tracanhphuonghoa1007
22-04-2024
3
2
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While effective vaccines are being administered globally, there is still a great need for antiviral therapies as antigenically novel SARS-CoV-2 variants continue to emerge across the globe. Viruses require host factors at every step in their life cycle, representing a rich pool of candidate targets for antiviral drug design.
18p
viellison
28-03-2024
1
1
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Human immunodeficiency virus-1-associated neurocognitive disorder is a known complication in individuals treated with antiretroviral therapy. Cerebrospinal fluid escape, which is defined as discordant higher cerebrospinal fluid viremia than plasma, may occur in antiretroviral therapy-experienced individuals.
4p
vigojek
02-02-2024
2
1
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Transplant recipients are at high risk of coronavirus disease 2019, and a timely supply of antivirals should be prioritized for those patients. Complicated drug‒drug interactions limit the use of Paxlovid (nirmatrelvir/ ritonavir) coadministered with tacrolimus.
4p
vitiki
30-01-2024
2
2
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Part 1 book "Canine and feline infectious diseases" includes content: Isolation in cell culture, immunoassays, nucleic acid detection assays, principles of antiinfective therapy, antiviral and immunomodulatory drugs, antibacterial drugs, antifungal drugs, antiprotozoal drugs, infection control programs for dogs and cats,.... and other contents.
285p
oursky09
12-11-2023
12
2
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Part 2 book "Principles of virology (4/E - Vol 2: Pathogenesis and control)" includes content: Human immunodeficiency virus pathogenesis, vaccines, antiviral drugs, evolution, emergence, unusual infectious agents.
221p
oursky07
24-10-2023
5
2
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At present, there are a variety of antiviral drugs for HBV in clinical practice, but there is no standard scheme for transcatheter arterial chemoembolization(TACE) combined with antiviral drugs. The aim of this study was to investigate whether TACE must be combined with antiviral therapy in patients of HBV-related hepatocellular carcinoma(HCC).
11p
vischultz
20-10-2023
4
1
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Part 2 book "Drug therapy for infectious diseases of the dog and cat" includes content: Imidocarb dipropionate, meglumine antimoniate, milbemycin oxime, ponazuril (toltrazuril sulfone), primaquine phosphate, pyrantel pamoate, potentiated sulfas, antiviral agents,... and other contents.
167p
oursky04
14-09-2023
3
2
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This work describes the electrochemical investigation of a promising antiviral agent, favipiravir (FAV) utilizing a nonmodified glassy carbon (GC) electrode, along with a unique voltammetric approach that can determine FAV with a good degree of accuracy, speed, and cost-effectiveness. Using cyclic voltammetry, the compound demonstrated a single well-defined and an irreversible oxidation peak at approximately +1.12 V (vs. Ag/AgCl) in Britton–Robinson (BR) buffer at pH 10.0.
12p
lyhuyenthu
31-01-2023
5
2
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Feline calicivirus (FCV) is a common and highly prevalent pathogen causing upper respiratory diseases in kittens and felines in recent years. Due to the substantial genetic variability of the viral genes, existing vaccines cannot provide complete protection. Therefore, research on FCV antiviral drugs has received much attention.
9p
vigandhi
23-02-2022
14
1
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The effects of ionic strength and temperature on the dissociation constants of adefovir (PMEA) and cidofovir (HPMPC) used as antiviral drugs were studied at 298 K, 308 K, and 318 K in aqueous media and at different ionic strength backgrounds of NaCl potentiometrically. The dissociation constants of the ligands were determined via the calculation of the titration data with the SUPERQUAD computer program. The thermodynamic parameters (∆G, ∆H , and ∆S) for all species were calculated.
9p
langthannam
29-12-2021
6
0
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A series of novel thiazoles and 1,3-thiazine derivatives were synthesized in good yield via reaction of ethyl 3-(1-(2-thiocarbamoylhydrazono)ethyl)-1,5-diphenyl-1H -pyrazole-4-carboxylate with hydrazonoyl halides and arylidenemalononitriles, respectively. The structure of the newly synthesized products was elucidated via elemental analysis, spectral data, and alternative routes whenever possible. Moreover, the antiviral screening of the products was evaluated and the results revealed that some of them have strong to moderate potency against the rabies virus compared with the reference drug.
13p
langthannam
29-12-2021
6
0
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To investigate the risk of hepatitis B virus (HBV) reactivation in rheumatoid arthritis (RA) patients with HBV carrier state during treatment of disease-modifying antirheumatic drugs (DMARDs) and the use of antiviral prophylaxis in real-world clinical practice.
10p
vianttinic2711
20-04-2021
14
2
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Host factors of influenza virus replication are often found in key topological positions within proteinprotein interaction networks. This work explores how protein states can be manipulated through controllability analysis: the determination of the minimum manipulation needed to drive the cell system to any desired state.
13p
vijisoo2711
27-10-2020
7
0
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Researchers have extensively focused on marine originated antimicrobial drugs, looking at the fact that terrestrial source of antibiotics are exhausted and demand of newer class of antimicrobials due to ever increasing resistance level in existing drug classes. Antibiotics like antibacterial, antiviral, antifungal agents are among the pharmaceutical agents being developed from marine resources (Mayer and Hamann, 2002).
6p
cothumenhmong7
09-09-2020
14
1
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Etravirine (ETV) was approved as the second generation drug for use in individuals infected with HIV-1 in 2008 by the U.S. FDA with its unique antiviral activity, high specificity, and low toxicity. However, there are some shortcomings of the existing synthetic routes, such as the long reaction time and poor yield.
6p
vijiraiya2711
27-05-2020
8
1
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The selectivity index of these compounds is similar to that of cidofovir. Although antiviral activity was evident in secondary assays, significant virus inhibition occurred at or near the cytotoxic concentration (SI90=1).
8p
tocectocec
25-05-2020
9
0
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