Association mapping

Double-strand breaks (DSBs) result from the attack of both DNA strands by multiple sources, including radiation and chemicals. DSBs can cause the abnormal chromosomal rearrangements associated with cancer. Recent techniques allow the genome-wide mapping of DSBs at high resolution, enabling the comprehensive study of their origins.

14p vimichaelfaraday 25-03-2022 17 1   Download

Upland rice grows on 19 million ha, about 15% of the world's rice plantation [2]. The production of upland rice is crucial to agricultural economy of many countries [15]. The yield of upland rice is very low with an average of about 1 t/ha. Drought is a major constraint to the productivity of upland rice.

10p 12120609 01-06-2020 11 1   Download

Understanding the genetic complexity of traits is an important objective of small grain temperate cereals yield and adaptation improvements. Bi-parental quantitative trait loci (QTL) linkage mapping is a powerful method to identify genetic regions that co-segregate in the trait of interest within the research population. However, recently, association or linkage disequilibrium (LD) mapping using a genome-wide association study (GWAS) became an approach for unraveling the molecular genetic basis underlying the natural phenotypic variation.

17p partimesinhvien 08-05-2020 17 1   Download

Common rust, caused by Puccinia sorghi, is an important foliar disease of maize that has been associated with up to 50% grain yield loss. Development of resistant maize germplasm is the ideal strategy to combat P. sorghi.

14p vishikamaru2711 29-04-2020 10 0   Download

Protein MUTYH là enzyme DNA glycosylase có vai trò quan trọng trong hệ thống sửa chữa cắt bỏ base giúp ngăn chặn các đột biến do các gốc oxy hóa tự do. Các đột biến ở gen MUTYH gây nên bệnh đa polyp liên quan đến gen MUTYH (MAP - MUTYH -associated polyposis) dẫn đến ung thư đại trực tràng.

5p vihermes2711 03-10-2019 40 0   Download

We reported previously on the purification and partial characterization of a putative microtubule-associated protein (MAP) from bovine adrenal cor-tex with an approximate molecular mass of 250 kDa. The protein was expressed ubiquitously in mammalian tissues, and bound to microtubules in vitro and in vivo, but failed to promote tubulin polymerization into microtubules. In the present study, partial amino acid sequencing revealed that the protein shares an identical primary structure with the widely distri-buted iron storage protein, ferritin....

0p awards 05-04-2013 50 2   Download

he 8.5 kDa chloroplast protein CP12 is essential for assembly of the phosphoribulokinase⁄glyceraldehyde-3-phosphate dehydrogenase (GAPDH) complex fromChlamydomonas reinhardtii. After reduction of this complex with thioredoxin, phosphoribulokinase is released but CP12 remains tightly associated with GAPDH and downregulates its NADPH-dependent activity.

12p inspiron33 25-03-2013 38 4   Download

Eph receptor tyrosine kinases regulate many important biological pro-cesses. In the present study, we explored the substrate specificity of the EphA4 receptor tyrosine kinase using peptide arrays. We define a consen-sus substrate motif for EphA4 and go on to identify and test a number of potential EphA4 substrates and map their putative site(s) of phosphoryla-tion.

11p media19 06-03-2013 47 4   Download

Strategies for the chemical construction of synthetic proteins with precisely positioned post-translational modifications or their mimics offer a powerful method for dissecting the complexity of functional protein alteration and the associated complexity of proteomes.

11p media19 06-03-2013 48 2   Download

In many laboratories, the requirement of microtubule-associated proteins (MAPs) and the stabilization of microtubules for the elongation of neurites has been intensively investigated, with controversial results being obtained. We have observed that the neurite microtubules of Cath.a-differentiated (CAD) cells, a mouse brain derived cell, are highly dynamic structures, and so we analyzed several aspects of the cytoskeleton to investigate the molecu-lar causes of this phenomenon.

14p vinaphone15 25-02-2013 40 4   Download

The interplay between geometry and topology on complex algebraic varieties is a classical theme that goes back to Lefschetz [L] and Zariski [Z] and is always present on the scene; see for instance the work by Libgober [Li]. In this paper we study complements of hypersurfaces, with special attention to the case of hyperplane arrangements as discussed in Orlik-Terao’s book [OT1]. Theorem 1 expresses the degree of the gradient map associated to any homogeneous polynomial h as the number of n-cells that have to be added to a generic hyperplane section D(h) ∩ H to obtain the complement in...

36p tuanloccuoi 04-01-2013 225 7   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Association mapping and marker-assisted selection of the lettuce dieback resistance gene Tvr1

0p panasonic06 25-12-2011 34 3   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Association mapping of common bacterial blight resistance QTL in Ontario bean breeding populations

11p panasonic02 14-12-2011 40 6   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: A consensus linkage map for molecular markers and Quantitative Trait Loci associated with economically important traits in melon (Cucumis melo L.)

14p panasonic02 14-12-2011 74 4   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: A low-cost open-source SNP genotyping platform for association mapping applications...

11p thulanh19 09-11-2011 73 4   Download

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học quốc tế đề tài: Estimated breeding values and association mapping for persistency and total milk yield using natural cubic smoothing splines

13p toshiba18 08-11-2011 54 3   Download

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học quốc tế đề tài: Linear models for joint association and linkage QTL mapping

17p toshiba18 08-11-2011 66 6   Download

The Genetic Map Given the size and complexity of the human genome, initial efforts aimed at developing genetic maps to provide orientation and to delimit where a gene of interest may be located. A genetic map describes the order of genes and defines the position of a gene relative to other loci on the same chromosome. It is constructed by assessing how frequently two markers are inherited together (i.e., linked) by association studies. Distances of the genetic map are expressed in recombination units, or centiMorgans (cM).

5p konheokonmummim 03-12-2010 69 4   Download

BÀI 11 – ASSOCIATIVE CONTAINER (CÁC BỘ LƯU TRỮ LIÊN KẾT) Bao gồm map (ánh xạ) multimap (đa ánh xạ) set (tập hợp) multiset (đa tập hợp) Sự khác nhau giữa các associative container và sequential container ở một điểm: -các sequential container lưu trữ các phần tử (gọi là các value) và các value này được truy xuất tuần tự theo vị trí của chúng trong bộ lưu trữ -các associative container lưu trữ các phần tử (gọi là các value) và các khóa (gọi là các key) ......

6p yukogaru 26-07-2010 86 11   Download

XML is rapidly establishing itself as the metagrammar for interorganizational communication around the Internet. It is becoming increasingly urgent that business analysts, systems analysts, and software developers be able to: • model the information to be represented in XML. • describe the relationships between the XML and the systems to process it. Having done so, they must also be able to rapidly generate the boilerplate code associated with implementing these processes.

8p doxuan 07-08-2009 456 46   Download