Associations analysis

Part 1 book "Quantitative genetics, genomics and plant breeding" includes content: Quantitative genetics, genomics and the future of plant breeding; why quantitative geneticists should care about bioinformatics; QTL analysis - problems and (possible) solutions; association mapping in plant populations; integrating molecular techniques into quantitative genetics and plant breeding; use of molecular markers in plant breeding - drought tolerance improvement in tropical maize, explorations with barley genome maps;... and other contents.

235p dianmotminh04 12-07-2024 0 0   Download

Part 1 of ebook "Introduction to statistics and data analysis: With exercises, solutions and applications in R" provides readers with contents including: Chapter 1 - Introduction and framework; Chapter 2 - Frequency measures and graphical representation of data; Chapter 3 - Measures of central tendency and dispersion; Chapter 4 - Association of two variables; Chapter 5 - Combinatorics; Chapter 6 - Elements of probability theory; Chapter 7 - Random variables; Chapter 8 - Probability distributions;...

185p daonhiennhien 03-07-2024 3 1   Download

Children are especially vulnerable to Toxocara infestation and its severe complications, however, there has not been any published data on the disease prevalence and treatment effectiveness in pediatric population. This paper was to present preliminary results of the study to determine the prevalence of toxocariasis in children aged 3 to 15 in Ho Chi Minh City (HCMC) and its associated factors.

9p vikoch 27-06-2024 1 1   Download

Gastric cancer (GC) is one of the most prevalent malignant tumors worldwide and is associated with high morbidity and mortality rates. However, the specific biomarkers used to predict the postoperative prognosis of patients with gastric cancer remain unknown. Recent research has shown that the tumor microenvironment (TME) has an increasingly positive effect on anti-tumor activity. This study aims to build signatures to study the effect of certain genes on gastric cancer.

17p vishanshan 27-06-2024 1 1   Download

The tripartite motif (TRIM) proteins have been reported to play crucial roles in various malignancies. However, the clinical significance of TRIM proteins in colorectal cancer (CRC) remains controversial. This study aimed to evaluate the association between TRIM proteins and the clinicopathological features and survival outcomes in patients with CRC.

9p vishanshan 27-06-2024 1 1   Download

Numerous studies have indicated that cancer-associated fibroblasts (CAFs) play a crucial role in the progression of colorectal cancer (CRC). However, there are still many unknowns regarding the exact role of CAF subtypes in CRC.

20p vishanshan 27-06-2024 1 1   Download

The aim of this study was to assess the knowledge, attitudes, and practices regarding cancer prevention, and associated characteristics to inform the development of targeted cancer prevention campaigns and policies.

10p vishanshan 27-06-2024 2 1   Download

Through research on the gut microbiota (GM), increasing evidence has indicated that the GM is associated with esophageal cancer (ESCA). However, the specific cause-and-effect relationship remains unclear. In this study, Mendelian randomization (MR) analysis was applied to investigate the causal relationship between the GM and ESCA, including its subtypes.

14p vishanshan 27-06-2024 2 1   Download

This study aimed to conduct a comprehensive analysis, evaluating the prognostic significance of the baseline Advanced Lung Cancer Inflammation Index (ALI) and Gustave Roussy Immune (GRIm) Score in patients undergoing immune checkpoint inhibitor (ICI) therapy.

13p vishanshan 27-06-2024 1 1   Download

Colorectal cancer (CRC) is the 3rd most common malignancy with the liver being the most common site of metastases. In this context, we conducted a metaanalysis to synthesize and evaluate the reliability of evidence pertaining to prognostic factors associated with early recurrence (ER) in CRLM following LR.

18p vishanshan 27-06-2024 1 1   Download

Multiple studies have indicated that patients with high body mass index (BMI) may have favourable survival outcomes following treatment with an immune checkpoint inhibitor (ICI). However, this evidence is limited by several factors, notably the minimal evidence from randomised controlled trials (RCTs), the use of categorised BMI with inconsistent cut point definitions, and minimal investigation of contemporary combination ICI therapy.

8p vishanshan 27-06-2024 1 1   Download

Evidence from observational studies suggests an association between chronic obstructive pulmonary disease (COPD) and lung cancer. The potential interactions between the immune system and the lungs may play a causative role in COPD and lung cancer and offer therapeutic prospects.

9p vishanshan 27-06-2024 1 1   Download

HBV infection is the leading risk factor for HCC. HBV infection has been confirmed to be associated with the exhaustion status of CD8+ T cells and immunotherapeutic efficacy in HCC. In this study, we aimed to investigate the prognostic value of the CD8+ T-cell exhaustion signature and immunotherapy response in patients with HBV-related HCC.

15p vishanshan 27-06-2024 1 1   Download

A psychoneurological symptom cluster composed of cancer-related fatigue, emotional distress, sleep difficulties, and pain is very common among patients with cancer. Cognitive difficulties are also frequently associated with this cluster. Network analyses allow for an in-depth understanding of the relationships between symptoms in a cluster.

7p vishanshan 27-06-2024 2 1   Download

This study aimed to identify new pyroptosis-associated tumor antigens for use in mRNA vaccines and the screening of sensitive LUAD populations suitable for vaccination. The association between tumor immune infiltrating cell abundance and potential tumor antigens was investigated and visualized using the analysis modules of gene expression, clinical outcomes, and somatic copy number variation.

15p vishanshan 27-06-2024 2 1   Download

Circulating cell-free DNA (cfDNA, liquid biopsy) is a powerful tool to detect molecular alterations. However, depending on tumor characteristics, biology and anatomic localization, cfDNA detection and analysis may be challenging. Gliomas are enclosed into an anatomic sanctuary, which obstacles the release of cfDNA into the peripheral blood.

10p vishanshan 27-06-2024 1 1   Download

To improve patient outcomes and provider team practice, the California Perinatal Quality Care Collaborative (CPQCC) created the Simulating Success quality improvement program to assist hospitals in implementing a neonatal resuscitation training curriculum. This study aimed to examine the costs associated with the design and implementation of the Simulating Success program.

10p vishanshan 27-06-2024 2 1   Download

While some of the observed historic variation in prescribing behaviour has been lessened by the process of inspection and ratings, we find this change is small and appears to come from both improvements among lowerrated practices and deteriorations among higher-rated practices. While inspection and rating no doubt had other impacts, these prescribing indicators were largely unchanged.

8p vishanshan 27-06-2024 1 1   Download

Nurses turnover intention, representing the extent to which nurses express a desire to leave their current positions, is a critical global public health challenge. This issue significantly affects the healthcare workforce, contributing to disruptions in healthcare delivery and organizational stability.

11p vishanshan 27-06-2024 3 1   Download

Prolonged standing at work may contribute to increased risk of musculoskeletal pain in home care workers. Patients’ activities of daily living (ADL) score may be a proxy for home care workers’ standing time at work. The objective of the present study was to investigate the association between patients’ ADL self-care score, and workers standing time.

9p vishanshan 27-06-2024 1 1   Download