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Asthma pathogenesis
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Part 2 book "Veterinary allergy" includes content: The pathogenesis of food allergy, cutaneous manifestations of food hypersensitivity, diagnostic workup of food hypersensitivity, flea biology and ecology, clinical signs of flea allergy dermatitis in dogs, diagnostic investigation of canine flea bite allergy,... and other contents.
248p
muasambanhan02
18-12-2023
1
0
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Part 1 book "Pediatric rhinosinusitis" includes content: Definitions and clinical signs and symptoms; burden and health impact of pediatric rhinosinusitis; pathogenesis of pediatric rhinosinusitis; imaging in pediatric rhinosinusitis; microbiology of pediatric sinusitis, the role of adenoids in pediatric sinusitis; allergy and sinusitis; rhinosinusitis and asthma in children; chronic rhinosinusitis in children with cystic fibrosis; sinusitis and immunodeficiency in children; pediatric rhinosinusitis and gastroesophageal reflux; pediatric sinusitis and adenoiditis.
160p
oursky09
12-11-2023
6
1
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Allergic asthma is a chronic airway inflammatory disease with a number of cytokines participating in its pathogenesis and progress. Interleukin (IL)-22, which is derived from lymphocytes, acts on epithelial cells and play a role in the chronic airway inflammation.
10p
vimackenziebezos
29-11-2021
13
1
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A number of studies have examined the association between mold exposure and childhood asthma. However, the conclusions were inconsistent, which might be partly attributable to the lack of consideration of gene function, especially the key genes afecting the pathogenesis of childhood asthma.
11p
vianthony2711
16-04-2021
11
2
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Neurokinins (NKs) participate in asthmatic airway inflammation, but the effects of NKs on airway smooth muscle cells (ASMCs) and those of corticosteroids on NKs are unknown. NK-1R is involved in the pathogenesis of asthma and that budesonide may downregulate the expression of NK-1R in the ASMCs and airways of asthmatic rats, which may alleviate neurogenic airway inflammation.
6p
vianthony2711
16-04-2021
11
2
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Impaired epithelial barrier function renders the airway vulnerable to environmental triggers associated with the pathogenesis of bronchial asthma. We investigated the influence of protocadherin-1 (PCDH1), a susceptibility gene for bronchial hyperresponsiveness, on airway epithelial barrier function.
12p
vimontana2711
05-04-2021
7
2
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As a main line of defense of the respiratory tract, the airway epithelium plays an important role in the pathogenesis of asthma. CDHR3 and EMSY were reported to be expressed in the human airway epithelium. Although previous genome-wide association studies found that the two genes were associated with asthma susceptibility, similar observations have not been made in the Chinese Han population.
9p
vimichigan2711
26-03-2021
10
2
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Persistent allergic airway diseases cause a great burden worldwide. Their pathogenesis is not clear enough. There is evidence that one of the recently described cytokine interleukin (IL) 22 may be involved in the pathogenesis of these diseases.
8p
vimichigan2711
26-03-2021
9
2
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The dysfunction of airway epithelial barrier is closely related to the pathogenesis of asthma. Secreted Hsp90α participates in inflammation and Hsp90 inhibitor protects endothelial dysfunction. In the current study, we aimed to explore the role of secreted Hsp90α in asthmatic airway epithelial barrier function.
12p
vimaine2711
26-03-2021
7
1
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Mitochondria contain their own DNA (MtDNA) that is very sensitive to oxidative stress and as a consequence could be damaged in quantity. Oxidative stress is largely recognized to play a key role in the pathogenesis of asthma and COPD and might have a role in the new intermediate phenotype ACOS (asthma-COPD overlap syndrome).
9p
vimaine2711
26-03-2021
9
2
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Recognition of the airway epithelium as a central mediator in the pathogenesis of asthma has necessitated greater understanding of the aberrant cellular mechanisms of the epithelium in asthma. The architecture of chromatin is integral to the regulation of gene expression and is determined by modifications to the surrounding histones and DNA.
11p
vimaine2711
26-03-2021
13
2
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The pathogenesis of asthma is a complex process involving multiple genes and pathways. Identifying biomarkers from asthma datasets, especially those that include heterogeneous subpopulations, is challenging.
13p
vicolorado2711
22-10-2020
8
0
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The CC-chemokine receptor 4 (CCR4) is thought potentially to play a critical role in asthma pathogenesis due to its ability to recruit type 2 T-helper lymphocytes to the inflamed airways. Therefore, CCR4 provides an excellent target for anti-inflammatory therapy.
11p
vienzym2711
03-04-2020
8
2
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Asthma is the most common chronic childhood disease. Imbalance of cytokines released from T helper cells and environmental factors, such as exposure to poly-aromatic hydrocarbon (PAH), play pivotal roles in the pathogenesis of asthma.
8p
vinatri2711
29-02-2020
14
1
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Asthma is a common respiratory disease with a high prevalence and morbidity that can seriously affect quality of life. Microbial colonization of the airway may participate in the pathogenesis of asthma, however the mechanisms involved have not been established. In the present study, we aimed to determine the composition of the microbiota in different asthmatic phenotypes from Northeast China.
9p
vinasaki2711
12-11-2019
11
1
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Wheezing appreciated on auscultation of the chest is the most common physical finding. The main physiological feature of asthma is episodic airway obstruction characterized by expiratory airflow limitation. The dominant pathological feature is airway inflammation, sometimes associated with airway structural changes. Asthma has significant genetic and environmental components, but since its pathogenesis is not clear, much of its definition is descriptive.
119p
dacotaikhoan
26-04-2013
56
2
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Air pollution is one of the most serious environmental threats to urban populations (Cohen 2005). Exposures vary among and within urban areas, but all people living in cities are exposed, and many are harmed, by current levels of pollutants in many large cities. Infants, young children, seniors and people who have lung and heart conditions are especially affected, but even young, healthy adults are not immune to harm from poor air quality.
42p
saimatkhauroi
01-02-2013
49
4
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Therapeutic immunosuppression has very broad applications in clinical medicine, ranging from prevention and treatment of organ and bone marrow transplant rejection, management of various autoimmune disorders (e.g., rheumatoid arthritis), skin diseases, allergies and asthma. Whereas traditionally only a small repertoire of immunosuppressive agents was available for clinical use, recent discoveries have significantly increased the number of approved agents, resulting in numerous trials to further evaluate their potential.
428p
wqwqwqwqwq
23-07-2012
98
7
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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: Th2 cytokines and asthma Interleukin-4: its role in the pathogenesis of asthma, and targeting it for asthma treatment with interleukin-4 receptor antagonists...
5p
toshiba13
22-10-2011
56
2
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Complex Genetic Disorders The expression of many common diseases such as cardiovascular disease, hypertension, diabetes, asthma, psychiatric disorders, and certain cancers is determined by a combination of genetic background, environmental factors, and lifestyle. A trait is called polygenic if multiple genes contribute to the phenotype or multifactorial if multiple genes are assumed to interact with environmental factors. Genetic models for these complex traits need to account for genetic heterogeneity and interactions with other genes and the environment.
7p
konheokonmummim
03-12-2010
68
3
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