Autoimmunity and transplantation

In the last decade, remarkable advances have been made in bone marrow transplantation (BMT), which is now becoming a powerful tool in the treatment of diseases such as leukemia, aplastic anemia, and congenital immunodeficiency. In animal experiments, it has been found that BMT can be used to treat not only systemic autoimmune diseases but also organ-specific autoimmune diseases. In humans, it has recently been shown that rheumatoid arthritis, ulcerative colitis, and Crohn's disease can be successfully treated after BMT.

335p vimeyers 29-05-2024 3 2   Download

Part 1 book "Laboratory medicine - The diagnosis of disease in the clinical laboratory" includes contents: Concepts in laboratory medicine, methods, autoimmune disorders involving the connective tissue and immunodeficiency diseases, histocompatibility testing and transplantation, infectious diseases, toxicology, diseases of infancy and childhood, blood vessels.

241p dianmotminh01 17-05-2024 5 3   Download

Initial comments on the effectiveness of surgical treatment of vitiligo Research subjects and methods: A prospective study on 12 cases of vitiligo that were successfully treated with autologous pigment cell transplant surgery. Research period from September 2018 to October 2022 at the Center for Plastic Surgery, Surgery & Regeneration - Le Huu Trac National Burn Hospital.

9p vioraclene 31-03-2024 6 2   Download

Pregnancy after liver transplantation poses a significant challenge to both the patient and the transplant team. We present the case of a 19-year-old European patient who underwent liver transplantation 5 years previously owing to autoimmune hepatitis.

9p vitiki 30-01-2024 2 2   Download

Autologous hematopoietic stem cell transplantation therapy has been widely used in recent decades for the treatment of hematological diseases, cancer, and autoimmune diseases. In autoimmune diseases, self-activated T lymphocytes and B lymphocytes secreting antibodies against host antigens are considered to be central in the pathogenesis of the disease.

7p vispacex 13-11-2023 6 2   Download

Part 2 book "Immunology" includes content: Immunity to protozoa and worms; primary immunodeficiencies; aids, secondary immunodeficiency and immunosuppression; vaccination; immunological tolerance; autoimmunity and autoimmune disease; transplantation and rejection; immunity to cancers; immediate hypersensitivity; hypersensitivity; hypersensitivity; hypersensitivity.

289p oursky08 04-11-2023 1 1   Download

Systemic lupus erythematosus (SLE) is a chronic disease that causes systemic inflammation which affects multiple organs. There is no cure for SLE. Conventional treatment options include antimalarial drugs, corticosteroids, and immune suppressants, but a number of patients are resistant to treatment or suffer from severe side effects.

6p visoros 01-11-2023 3 1   Download

Part 2 book "Lippincott's illustrated reviews, immunology" includes content: The well patient - how innate and adaptive immune responses maintain health; hypersensitivity reactions, immune deficiency, autoimmunity, transplantation, immune pharmacotherapy, tumor immunity, measurement of immune function

210p oursky05 20-09-2023 7 1   Download

End stage liver disease (ESLD) is associated with significant thrombotic complications. In this study, we attempted to determine if patients with ESLD, due to oncologic or autoimmune diseases, are susceptible to thrombosis to a greater extent than patients with ESLD due to other causes.

7p viisaacnewton 25-04-2022 19 1   Download

Highly polymorphic human leukocyte antigen (HLA) genes are responsible for fine-tuning the adaptive immune system. High-resolution HLA typing is important for the treatment of autoimmune and infectious diseases. Additionally, it is routinely performed for identifying matched donors in transplantation medicine.

10p vibeauty 23-10-2021 3 0   Download

Anti-CD3 immunotherapy was initially approved for clinical use for renal transplantation rejection prevention. Subsequently, new generations of anti-CD3 antibodies have entered clinical trials for a broader spectrum of therapeutic applications, including cancer and autoimmune diseases.

14p visilicon2711 20-08-2021 11 1   Download

Human leukocyte antigen (HLA) genes are critical genes involved in important biomedical aspects, including organ transplantation, autoimmune diseases and infectious diseases. The gene family contains the most polymorphic genes in humans and the difference between two alleles is only a single base pair substitution in many cases.

10p vikentucky2711 26-11-2020 12 1   Download

Renal cell carcinoma (RCC) is a tumor with immunogenic properties. Soluble interleukin-2 receptor (sIL-2R) has a role in T cell activation and may be important for immune regulation in various conditions, including infections, transplantation rejection, autoimmune inflammatory states, and cancer.

10p vidhaka2711 31-07-2020 10 1   Download

CD40, also called Bp50, is a novel member of the TNF receptor superfamily. Based on its important role in multiple physiological and pathological processes, the CD40 signaling pathway has become a vital target for treating transplantation, autoimmune diseases and cancers.

10p viuchiha2711 21-04-2020 11 0   Download

Long-term administration of classic immunosuppressants can induce severe adverse effects. The development of novel immunosuppressants confronts great challenges and opportunities. Ibrutinib, an approved drug for B-cell lineages and chronic graft versus host disease (cGVHD), exhibits immunosuppressive efficacy in autoimmune diseases.

11p vihasaki2711 12-11-2019 13 1   Download

CD8+CD28-T cells (CD8Ts) exert immunosuppressive effects in various autoimmune diseases. The current study was designed to investigate the role of defects in CD8Ts in liver transplantation (LT). The proportion of CD8Ts in peripheral blood was determined by flow cytometry.

8p vihasaki2711 12-11-2019 11 0   Download

Despite an increase in the development of biological therapies for autoimmune disease (AID), a proportion of patients remain treatment refractory, resulting in long term morbidity and increased rates of mortality. Furthermore, maintenance biologic therapies are associated with treatment-related side effects, significant financial cost, and restricted access, which is of particular relevance in the developing world.

10p viconandoyle2711 03-09-2019 8 0   Download

(BQ) Continued part 1, part 2 of the document Biology and immuno (Ninth edition) has contents: The mucosal immune system, manipulation of the immune response, autoimmunity and transplantation, failures of host defense mechanisms, allergy and allergic diseases,... and other contents. Invite you to refer.

0p thuongdanguyetan06 06-06-2019 20 1   Download

part 1 book “essentials of clinical immunology” has contents: basic components - structure and function, infection, immunodeficiency, anaphylaxis and allergy, autoimmunity, lymphoproliferative disorders, immune manipulation, transplantation, kidney diseases.

187p tieu_vu13 06-08-2018 32 3   Download

(BQ) Continued part 1, part 2 of the document Cellular and molecular immunology presents the following contents: Differentiation and functions of CD8+ effector T cells; B cell activation and antibody production, immunologic tolerance and autoimmunity, effector mechanisms of humoral immunity, immunity to microbes, transplantation immunology,...

307p thangnamvoiva5 14-07-2016 37 1   Download