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Bacterial operons
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Efficient regulation of bacterial genes in response to the environmental stimulus results in unique gene clusters known as operons. Lack of complete operonic reference and functional information makes the prediction of metagenomic operons a challenging task; thus, opening new perspectives on the interpretation of the host-microbe interactions.
14p
vilichoo2711
25-06-2021
14
1
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Differential RNA sequencing (dRNA-seq) is a high-throughput screening technique designed to examine the architecture of bacterial operons in general and the precise position of transcription start sites (TSS) in particular.
11p
vikentucky2711
26-11-2020
11
0
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Inferring operon maps is crucial to understanding the regulatory networks of prokaryotic genomes. Recently, RNA-seq based transcriptome studies revealed that in many bacterial species the operon structure vary with the change of environmental conditions.
14p
vikentucky2711
26-11-2020
5
0
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We are creating software for agent-based simulation and visualization of bio-molecular processes in bacterial and eukaryotic cells. As a first example, we have built a 3-dimensional, interactive computer model of an Escherichia coli bacterium and its associated biomolecular processes.
23p
vikentucky2711
24-11-2020
7
1
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Bacterial operons are considerably more complex than what were thought. At least their components are dynamically rather than statically defined as previously assumed. Here we present a computational study of the landscape of the transcriptional units (TUs) of E. coli K12, revealed by the available genomic and transcriptomic data, providing new understanding about the complexity of TUs as a whole encoded in the genome of E. coli K12.
9p
vioklahoma2711
19-11-2020
8
2
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The order of genes in bacterial genomes is not random; for example, the products of genes belonging to an operon work together in the same pathway. The cotranslational assembly of protein complexes is deemed to conserve genomic neighborhoods even stronger than a common function.
8p
vicolorado2711
23-10-2020
27
1
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Violacein is a deep violet compound that is produced by a number of bacterial species. It is synthesized from tryptophan by a pathway that involves the sequential action of 5 different enzymes (encoded by genes vioA to vioE).
8p
vihamax2711
21-04-2020
10
1
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In chapter 7 we will explore one strategy bacteria employ to control the expression of their genes: by grouping functionally related genes together so they can be regulated together easily. Such a group of contiguous, coordinately controlled genes is called an operon.
49p
tangtuy05
30-03-2016
56
2
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Chapter 7 - Operons: Fine control of bacterial transcription. In this chapter we will explore one strategy bacteria employ to control the expression of their genes: by grouping functionally related genes together so they can be regulated together easily. Such a group of contiguous, coordinately controlled genes is called an operon.
47p
tangtuy02
08-03-2016
58
2
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Chapter 18 - Regulation of gene expression. When you finish this chapter, you should: Explain the concept of an operon and the function of the operator, repressor, and corepressor; explain the adaptive advantage of grouping bacterial genes into an operon; explain how repressible and inducible operons differ and how those differences reflect differences in the pathways they control;...
49p
tangtuy02
08-03-2016
30
2
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The Na + F1F0 ATP synthase operon of the anaerobic, acetogenic bacte-rium Acetobacterium woodiiis unique because it encodes two types of csubunits, two identical 8 kDa bacterial F0-like csubunits (c2 and c3 ), with two transmembrane helices, and a 18 kDa eukaryal V0 -like (c1 ) csubunit, with four transmembrane helices but only one binding site.
9p
media19
06-03-2013
36
2
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SurE, the stationary-phase survival protein of Salmonella typhimurium, forms part of a stress survival operon regulated by the stationary-phase RNA polymerase alternative sigma factor. SurE is known to improve bacterial viability during stress conditions.
10p
vinaphone15
28-02-2013
26
1
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Mycobacterium tuberculosis, the most successful bacterial pathogen, causes tuberculosis, a disease that still causes more than 2 million deaths per year. ArylamineN-acetyltransferase is an enzyme that is conserved in most Mycobacteriumspp.
9p
cosis54
08-12-2012
47
3
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Nowadays, with over a thousand bacterial genomes sequenced, even greater opportunities have opened for experimental or computational global analysis of metabolism, physiology, and evolution. In particular, the access to comprehensive sets of molecular components (genes, proteins, regulatory signals) is at the basis of the development of novel integrative approaches, aiming at understanding the function of specific sets of these components (operons, regulons, metabolic pathways, protein complexes, etc.) in the context of the whole organism.
0p
bachduong1311
07-12-2012
53
3
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