Basics of nucleic acids

In ebook "Nucleic acid drugs (Advances in Polymer science, Volume 249)" the basic concept of antisense and siRNA strategies is summarized by Dr. Yano of Nippon Shinyaku Co. The antisense strategy can be regarded as the striking NAD concept that was logically innovated in the mid-1970s. Originally, oligonucleotides complementary to mRNAs were thought to physically block translational steps in gene expression resulting in the blocking of protein synthesis.

189p coduathanh1122 27-03-2024 1 1   Download

Ebook "Extracellular nucleic acids (Nucleic acids and molecular biology, Volume 25)" covers nearly all of the newly developing fields related to extracellular nucleic acids, including those of basic biology, ecology and the medical sciences, and provides readers with the latest knowledge on them. Extracellular nucleic acids have recently emerged as important players in the fields of biology and the medical sciences.

239p cotieubac1004 15-03-2024 0 0   Download

Part 1 book "Biochemistry for dummies" includes content: Biochemistry - What you need to know and why; seems so basic - water chemistry and Ph, fun with carbon - organic chemistry; amino acids - the building blocks of protein; protein structure and function enzyme kinetics - getting there faster, what we crave - carbohydrates; lipids and membranes, nucleic acids and the code of life.

170p oursky05 20-09-2023 6 3   Download

Clustered regularly interspaced short palindromic repeats/CRISPR-associated proteins (CRISPR/Cas) is an acquired immune system found in bacteria and archaea that can specifically silence or degrade a foreign single or double strand nucleic acid to protect it from infection. In recent years, the CRISPR/Cas9 system has rapidly been evolved into a genome editing technology, in which the Cas9 endonuclease can be targeted to specific DNA sequences by guide RNAs (gRNAs) that are easily programmable.

16p tudichquannguyet 29-11-2021 21 1   Download

Lecture Basic Biomechanics (6e) - Chapter 2: Kinematic concepts for analyzing human motion. This chapter presents the following content: From atoms to molecules, water and living things, molecules of life, carbohydrates, lipids, proteins, nucleic acids.

20p nanhankhuoctai9 23-07-2020 17 1   Download

(bq) part 1 book "molecular diagnostics for dermatology" presents the following contents: introduction, basics of nucleic acids and molecular biology, molecular methods; risk assessment, diagnosis, and prognosis - using molecular tools to diagnose melanoma, predict its behavior and evaluate for inheritable forms,...

182p thangnamvoiva5 14-07-2016 64 2   Download

Chapter 23 introduce to carbohydrates and nucleic acids. After completing this chapter, students will be able to: Draw and identify the structures of glucose, its anomers, and its epimers, as Fischer projections and as chair conformations; correctly name monosaccharides and disaccharides, and draw their structures from their names; predict the reactions of carbohydrates in acidic and basic solutions, and with oxidizing and reducing agents;...

59p tangtuy02 11-03-2016 52 3   Download

After completing this chapter, students will be able to: Know the basic structures of nucleosides, nucleotides, and nucleic acids; know the difference between the syn and anti conformation of nucleotides and nucleosides; know the actual structures of the 4 deoxyribonucleotide triphosphates (dATP, dCTP, dGTP, dTTP), and the 4 ribonucleotide triphosphates (ATP, CTP, GTP, UTP). Know which ones are purines and which ones are pyrimidines. Draw all in anti conformation;...

25p tangtuy02 08-03-2016 40 2   Download

Translin protein is highly conserved in eukaryotes. Human translin binds both ssDNA and RNA. Its nucleic acid binding site results from a combina-tion of basic regions in the octameric structure. We report here the first bio-chemical characterization of wild-typeDrosophila melanogaster(drosophila) translin and a chimeric translin, and present 3.5 A ˚ resolution crystal struc-tures of drosophila P168S mutant translin from two crystal forms.

15p galaxyss3 07-03-2013 52 3   Download

RNomics is a newly emerging sub-discipline of genomics that categorically studies the structure, function and processes of non-coding ribo nucleic acids in a cell. MicroRNomics is a sub-field of RNomics that describes the biogenesis and mechanisms of tiny RNA regulators, and their involvement in the processes of development, differentiation, cell proliferation, cell death, chromosomal segregation and metabolism. The discovery of microRNAs in species ranging from Caenorhabditis elegans (C.

580p hyperion75 18-01-2013 60 7   Download

the micro- and nano- transport of biomolecules is of interest to a wide range of scientific and engineering communities. application areas include miniaturized technology that will support and advance key sectors, including healthcare, food provisioning, environment services, etc. this is generally intended for undergraduate students from chemical, life and physical sciences wanting to find out about the basic properties of biomolecules and how they can be transported in liquids on the micro- to nano-scale.

0p sn_buon 29-11-2012 52 3   Download

Developing countries devote all their available capacities to safeguard their small and poor farmers from being sidelined by things like growing competition through efficient support measures. They use their flexibilities to provide production-linked support to the fullest extent as, on the one hand, such payments are easier to administer and as they help creating basic food security by increasing production of staple crops. Support to rural development in general and to the environment would rank lower.

36p tieuyeuquai456 08-10-2012 64 2   Download

Information about plant genetic diversity is necessary for the development of appropriate strategies in conservation biology as well as in many other applied fields. From a basic evolutionary standpoint, genetic diversity is assumed to be crucial for the evolutionary potential of a species. Research programs that aim to investigate population structure provide evolutionary insights into the demographic patterns of diverse organisms (Milligan et al., 1994).

576p conquynho32 18-09-2012 74 8   Download

This book focuses on the basic electrochemical applications of DNA in various areas, from basic principles to the most recent discoveries. The book comprises theoretical and experimental analysis of various properties of nucleic acids, research methods, and some promising applications.

59p beobobeo 01-08-2012 101 22   Download

The field of biochemistry is diverse and forms parts of diverse fields including cell biology, molecular biology and medical sciences. Biochemistry is the study of the molecules of life like proteins, lipids, carbohydrates and nucleic acids. Studying the structure, properties and reactions of these important molecules would help in better understanding life as a whole. The practical aspect along with the theoretical background would help in better understanding these mechanisms. This book tries to address and compile some of the routinely used protocols in biochemistry for easy access.

142p chuyenphimbuon 21-07-2012 90 12   Download