Beta cell

Lung adenocarcinoma is the main type of lung cancer in women. Our previous findings have evidenced that 25-hydroxycholesterol (25-HC) promotes migration and invasion of lung adenocarcinoma cells (LAC), during which LXR as a 25-HC receptor plays an important role.

14p vishanshan 27-06-2024 2 1   Download

Hepatocellular carcinoma (HCC) is the most common type of malignant liver tumor with poor prognosis. In this study, we investigated the expression of transforming growth factor beta regulator 4 (TBRG4) in HCC and its effects on the proliferation, invasion, and metastasis of HCC cells, and analyzed the possible molecular mechanisms.

17p vikoch 27-06-2024 1 1   Download

Part 3 book "Basic and clinical pharmacology" includes contents: Beta lactam and other cell wall and membrane active antibiotics; tetracyclines, macrolides, clindamycin, chloramphenicol, streptogramins and oxazolidinones; aminoglycosides and spectinomycin; sulfonamides, trimethoprim, & quinolones; antimycobacterial drugs; antifungal agents; antiviral agents; miscellaneous antimicrobial agents disinfectants, antiseptics and sterilants,... and other contents.

686p dianmotminh01 17-05-2024 4 3   Download

Ebook "A systems biology approach to study metabolic syndrome" is to provide the target audience, specifically students of Medicine, Biology, Systems Biology and Bioinformatics, as well as experienced researchers in research fields relevant to metabolic syndrome (MetS) with an overview of the challenges and opportunities in systems biology and how it can be used to tackle MetS.

393p ladongphongthanh1008 22-04-2024 3 2   Download

We have previously reported an antigen-specific protocol to induce transplant tolerance and linked suppression to human embryonic stem cell (hESC)-derived tissues in immunocompetent mice through coreceptor and costimulation blockade. However, the exact mechanisms of acquired immune tolerance in this model have remained unclear.

14p vibransone 28-03-2024 2 2   Download

The efficacy of checkpoint blockade immunotherapies in colorectal cancer is currently restricted to a minority of patients diagnosed with mismatch repair-deficient tumors having high mutation burden. However, this observation does not exclude the existence of neoantigen-specific T cells in colorectal cancers with low mutation burden and the exploitation of their anti-cancer potential for immunotherapy.

15p vibransone 28-03-2024 2 2   Download

Retinoid therapy is widely employed in clinical oncology to differentiate malignant cells into their more benign counterparts. However, certain high-risk cohorts, such as patients with MYCN-amplified neuroblastoma, are innately resistant to retinoid therapy.

22p vioraclene 31-03-2024 2 2   Download

T and B cell receptor (TCR, BCR) repertoires constitute the foundation of adaptive immunity. Adaptive immune receptor repertoire sequencing (AIRR-seq) is a common approach to study immune system dynamics. Understanding the genetic factors influencing the composition and dynamics of these repertoires is of major scientific and clinical importance.

19p vibransone 28-03-2024 3 2   Download

Ebook "Stem cell therapy for diabetes" provides essential reading for those especially interested in tracking the progress in applying of one of the most exciting new developments in bio-medicine towards a cure for diabetes. Stem Cell Therapy for Diabetes, one of the latest installments of the Stem Cell Biology and Regenerative Medicine series, reviews the three main approaches for generation of sufficient numbers of insulin-producing cells for restoration of an adequate beta-cell mass: beta-cell expansion, stem-cell differentiation, and nuclear reprogramming.

294p cotieubac1004 15-03-2024 0 0   Download

Single-cell RNA sequencing (scRNA-seq) provides valuable insights into human islet cell types and their corresponding stable gene expression profiles. However, this approach requires cell dissociation that complicates its utility in vivo.

24p vicwell 29-02-2024 2 1   Download

Permanent neonatal diabetes mellitus (PNDM) presents with dehydration and hyperglycemia, which usually occurs during the frst 12 months of life. Activating mutations of beta-cell adenosine triphosphate-sensitive potassium [KATP] channel subunits that cause opening of the channel are associated with PNDM.

5p vilazada 31-01-2024 5 2   Download

Type 1 diabetes mellitus (T1DM) is a lifelong diagnosis that involves immune-mediated damage of pancreatic beta cells and subsequent hyperglycemia, manifesting as: polyuria, polydipsia, polyphagia, and weight loss.

5p vitiki 30-01-2024 5 2   Download

Part 2 book "Small animal imaging" includes content: Cell tracking and transplant imaging; beta cell imaging as part of “imaging on metabolic diseases”; in vivo preclinical imaging of developmental biology; imaging in gynecology research; imaging in cardiovascular research; imaging in neurooncology; imaging in neurology research II - Exploring plasticity and cognitive networks by in vivo MRI,... and other contents.

355p muasambanhan03 02-01-2024 5 2   Download

Part 2 book "Canine and feline endocrinology" includes content: Diabetic ketoacidosis, beta cell neoplasia - insulinoma, canine hyperadrenocorticism; hyperadrenocorticism in cats; hypoadrenocorticism; pheochromocytoma and multiple endocrine neoplasia; glucocorticoid therapy; hypercalcemia and primary hyperparathyroidism; hypocalcemia and primary hypoparathyroidism.

355p muasambanhan01 13-12-2023 4 2   Download

Nonerythrocytic spectrin beta 1 (SPTBN1) is an important cytoskeletal protein that involves in normal cell growth and development via regulating TGFβ/Smad signaling pathway, and is aberrantly expressed in various cancer types.

20p vischultz 20-10-2023 2 1   Download

Heat shock protein beta-1 (HSPB1) is a crucial biomarker for pathological processes in various cancers. However, the clinical value and function of HSPB1 in breast cancer has not been extensively explored.

18p visharma 20-10-2023 5 2   Download

Nghiên cứu này giúp người đọc hiểu rõ hơn về cách thức thiết kế một vector tái tổ hợp hướng đến mục tiêu phát triển hệ thống xúc tác toàn tế bào (whole-cell biocatalysts), từ đó mở ra nhiều cơ hội tạo ra nhiều cấu trúc plasmid tái tổ hợp khác trong công nghệ protein tái tổ hợp.

5p vipierre 30-09-2023 8 3   Download

Cuproptosis is a newly discovered programmed cell death dependent on mitochondrial respiratory disorder induced by copper overload. Pyruvate dehydrogenase E1 subunit beta (PDHB) is one of the cuproptosis genesand is a nuclear-encoded pyruvate dehydrogenase, which catalyzes the conversion of pyruvate to acetyl coenzyme A.

13p vioracle 29-09-2023 8 2   Download

Chronic obstructive pulmonary disease (COPD) is a common disease which negatively affects living quality and longevity of patients. Unfortunately, current COPD treatments are not radical. COPD is characterized by persistent neutrophil infiltrations mediated by inflammatory cytokines including interleukin (IL)-1β and IL-8 in the airway.

13p vimulcahy 18-09-2023 4 2   Download

Subcutaneous panniculitis like T-cell Lymphoma (SPTCL) - U lympho T dạng viêm mô mỡ dưới da là bệnh lý u lympho T nguyên phát tại da có biểu hiện lâm sàng giống viêm mô mỡ dưới da, đặc trưng bởi nhiều nốt hoặc các mảng thâm nhiễm dưới da, thường xuất hiện ở các chi và thường tiên lượng xấu nếu có kèm theo hội chứng thực bào máu.

9p viberbers 09-08-2023 3 2   Download