Beta lactamase prevalence

. This study was carried out on 120 urine specimen collected from catheterized patients, aged between 20-70 yrs. The screening for ESBL production was done by the disc diffusion test as recommended by the Clinical and Laboratory Standards Institute(CLSI) and confirmed by the phenotypic disc confirmatory test (PDCT) and ESBL Hi Crome agar(Hi media-Mumbai).

6p chauchaungayxua12 29-07-2021 4 1   Download

The study was aimed to detect the occurrence and characterize extended-spectrum (ESBL) and AmpC (ACBL) beta-lactamases producing pathogenic E. coli (STEC) in diarrhoeal faecal samples collected from bovines. All the E. coli strains (13/21, 61.9%) isolated from bovine diarrhoea cases (n=21) were found to be ESBL producers. In total, 11 (84.6%) isolates were positive in cefoxitin– cloxacillin double-disc synergy (CC-DDS) test for AmpC production and the isolates were also confirmed by PCR for blaAmpC.

11p chauchaungayxua10 19-03-2021 8 2   Download

Beta-lactam antibiotics are the most commonly used antimicrobials against bacterial infections. In recent years, emergence of resistance to these antimicrobial agents due to production of β-lactamases has become a serious global health concern. It was reported as leading cause to ineffectiveness to antibiotic usage, increased morbidity and high cost of treatment. Extended spectrum beta-lactamases (ESBLs) detection amongst the Gram – negative bacilli is considered as an important marker of endemicity.

9p caygaocaolon8 07-11-2020 8 1   Download

Extended spectrum beta lactamase producers are posing a major obstacle in the therapeutic outcome of patients. They cause enzymatic hydrolysis of the beta lactum ring, resulting in resistance to penicillins and cephalosporins. The rise in ESBL producers results in prolonged treatment which leads to increased hospital stay and financial burden on the patient. It is necessary for all the hospitals to monitor ESBL producers to formulate preventive and therapeutic measures accordingly. The study was conducted in a tertiary care hospital during the period from December 2015 to November 2016.

7p angicungduoc8 07-11-2020 15 1   Download

Escherichia coli is the most common organism causing urinary tract infection (UTI). This organism has the ability to produce Extended Spectrum Beta Lactamases (ESBLs), which confer multiple drug resistance making urinary tract infection difficult to treat. So treatment of UTI requires constant updating of the antibiotic sensitivity profile. Objectives of this study were to detect prevalence of ESBL production among E. coli isolates causing urinary tract infection and to detect their antibiotic susceptibility pattern.

8p trinhthamhodang1215 23-09-2020 25 1   Download

The main aim and objectives of this study includes to determine the Bacterial profile and their Anti-microbial susceptibility pattern of microbes in UTI patients and to detect and evaluate the prevalence of Extended Spectrum Beta Lactamase (ESBL) producing Gram Negative Uropathogens among the isolates. Also to determine the Antimicrobial susceptibility pattern for ESBL producers and ESBL non producers.

9p cothumenhmong7 09-09-2020 17 2   Download

The main aim of this study includes, to isolate and speciate the Klebsiella isolates from various clinical specimens from patients admitted in ICU. To determine the antibiotic susceptibility pattern of Klebsiella species by disc diffusion method. And to detect the presence of extended spectrum betalactamases (ESBL) by double disc synergy test and Inhibitor Potentiated disc diffusion test.

22p dayhoctainha 10-09-2020 25 1   Download

Neonatal septicemia is responsible for nearly half of neonatal deaths. With emerging drug resistance mechanisms like Metallo Beta lactamase (MBL) production, treatment of neonatal sepsis has become a challenge. The present study was done to identify prevalence of bacterial pathogens, their resistance profile and incidence of MBL mediated resistance among Gram negative bacterial isolates in neonatal sepsis. Seventy three cases of suspected neonatal septicemia were included in this prospective study. Blood culture was done by BacT/Alert 3D system, bacterial isolates were identified.

7p angicungduoc6 20-07-2020 10 1   Download

Microbiological infection plays vital role in determining the outcome as well as cost and duration of the hospital stay for patients admitted in ICU setup. Of late nosocomial infections especially ventilator associated pneumonias (VAP) have been recognized to be associated with significant morbidity and mortality in intubated patients. It is of critical importance to do regular surveillance of important pathogen (like Methicillin resistant staphylococcus aureus (MRSA), extended spectrum beta lactamase (ESBL) and carbapenemase producers) and its resistance pattern.

12p kethamoi6 29-06-2020 21 2   Download

Pseudomonas aeruginosa is an opportunistic pathogenic bacterium responsible for both acute and chronic infection causing serious infections in patients who are mechanically ventilated individuals, who are immunocompromised, and patients with malignancies or HIV infection. The present study was undertaken with the aim to find prevalence of Metallo-β-Lactamases producing Pseudomonas aeruginosa among clinical isolates by different phenotypic confirmatory methods.

7p nguaconbaynhay6 24-06-2020 14 1   Download

The infection of diabetic foot ulcer is a debilitating complication of long standing diabetes especially with resistant bacteria. The production of extended spectrum beta-lactamase (ESBL) by gram negative bacteria is widely prevalent. This study was carried out to identify the prevalence, antimicrobial resistant pattern, ESBL production and the presence of TEM and SHV genes among ESBL producing Escherichia Coli.

14p nguaconbaynhay6 23-06-2020 16 0   Download

To isolate the bacterial pathogens causing asymptomatic bacteriuria in antenatal women,to study the drug resistance pattern and prevalence of MRSA and ESBL producers. Bacterial pathogens were isolated from 1000 urine samples collected from antenatal women following standard procedures. All the isolates were studied for antibiotic susceptibility pattern using modified Kirby bauer disc diffusion method. Resistant isolates were identified and studied for MRSA and ESBL by various methods. Out of 1000 urine samples culture positive were 118(11.8%). E.

9p nguaconbaynhay6 23-06-2020 18 1   Download

Acinetobacter the aerobic non fermenting GNCB are emerging as important pathogens in health care associated infection, exhibiting increased antimicrobial resistance by virtue of multiple resistant mechanisms with practically no therapeutic options. The objective was to determine the multitude of resistant mechanisms by phenotypic and genotypic characterization and the prevalent antimicrobial susceptibility pattern. 175 clinically significant non-duplicate Acinetobacter isolates were included.

10p nguaconbaynhay6 23-06-2020 12 1   Download

Acinetobacter species are the commonest pathogens causing nosocomial infections. Acinetobacter is essentially resistant to many antibiotics and they are known to produce extended spectrum beta lactamase and metalo beta lactamase. Aim of the study is to detect Metalo beta lactamase producing Acinetobacter spp. from clinical samples in tertiary care hospital. Between January 2015 and June 2015, total 368 Acinetobacter spp were isolated from different clinical samples.

10p gaocaolon5 14-06-2020 10 1   Download

About 150 million people suffer from urinary tract infection each year. In majority of cases, treatment is initiated empirically based on the antimicrobial resistance pattern of the urinary pathogens prevalent in a particular setting. Emerging antibiotic resistance among Enterobacteriaceae has posed challenges in choosing empiric regimens. Therefore, the present study was designed to identify etiological agents of urinary tract infections, detect ESBL producing uropathogens and study their antibiotic resistance profile.

11p trinhthamhodang1213 30-05-2020 16 0   Download

This situation prompts early and accurate detection of MBL producers. Hence the present study was done to phenotypically evaluate the prevalence of MBL production among 235 clinical isolates of Pseudomonas aeruginosa (183) and Acinetobacter species (52). The antimicrobial susceptibility testing was done by Kirby Bauer disk diffusion method.

11p trinhthamhodang5 16-05-2020 13 1   Download

Non fermenting Gram Negative Bacilli (NFGNB) once considered as contaminants, now emerged as a major cause of life threatening nosocomial infections and as multidrug resistant pathogens. Acinetobacter species are the opportunistic pathogens with increasing prevalance in the nosocomial infections. Community acquired infections are also common in Acinetobacter. It accounts for 10% of all community-acquired bacteremic pneumonias. To isolate, identify and detect Carbapenem resistance producing Acinetobacter spp., and confirm Metallo Beta Lactamase ( MBL) production by phenotypic methods.

10p trinhthamhodang5 16-05-2020 15 1   Download

Urinary tract infections are the commonest infectious disease, seeking medical consultation and antibiotic therapy worldwide. Klebsiella pneumonia is among the most common uropathogen responsible for recurrent infections and it antimicrobial susceptibility to commonly prescribed drugs vary significantly in different regions. Hence, the objective was to analyze the local etiology and antimicrobial susceptibility pattern of urinary K. pneumonia, to optimize the rational empirical therapy.

5p nguathienthan4 18-04-2020 26 1   Download

Hospital acquired infections are one of the major causes of morbidity and mortality in hospitalized patients, leading to an enormous increase in the cost of hospital care and to the emergence of new health hazards for the community. The study aimed to determine the bacteriological profile of hospital acquired infections along with prevalence of multidrug resistance and extended spectrum beta lactamase (ESBL) enzymes amongst the isolates. A total of 180 isolates of various organisms were isolated from different clinical samples during a period of one year from January 2014 to December 2014.

7p quenchua4 06-04-2020 19 0   Download

In the current study prevalence and characterization of extended spectrum betalactamase(ESBL) production of Escherichia coli was detected from broilers of West Bengal, India. A total of 248 cloacal swabs samples were examined for E.coli by standard bacteriological techniques. E.coli isolates were serotyped and also screened for extended spectrum beta-lactamase by double disc diffusion assay and by PCR detection of blaCTX-M, blaSHV, and blaTEM genes.

9p caygaocaolon4 04-04-2020 14 1   Download