Bioactivity of products

This thesis documents a research program in which Australian grown Danshen extracts and related bioactive compounds have been demonstrated to be effective in scavenging free radicals, namely ROS generation, in a cell free system and NADPH oxidase derived superoxide (O2-) generation in vascular tissue (rat aorta). Danshen extracts, both aqueous and ethanol, and their active compounds (Tanshinone IIA, Salvianolic Acid B and Danshensu) demonstrated anti-oxidant activity however findings exhibited stronger activity in a cell free system than in the aortic vascular tissue.

138p runthenight07 01-03-2023 10 3   Download

Enhance and improve the bioavailability of the bioactive compounds in garlic through the processing of garlic products (black garlic and lactic acid bacteria fermentation garlic) and nanotechnology.

42p gaocaolon12 18-06-2021 16 4   Download

Objectives of the study: Survey of biological activity of alkaloid isolated from hairy roots of E.longifolia to find new activities. Determining optimal culture conditions for E.longifolia hairy roots to grow and develop. Determining the concentration of three elicitors (Salicylic acid, Jasmonic acid and Yeat extract) on the production and accumulation of alkaloids isolated from hairy roots of E.longifolia in vitro.

26p extraenglish 24-05-2021 30 5   Download

The objective of the thesis is to successfully build up a process for preparation of bioactive water-soluble low molecular weight β-glucan product from from spent brewer’ yeast by irradiation method.

31p capheviahe26 25-01-2021 42 5   Download

Preliminary experiments shows, that [3+2] cycloadditions reactions proceeds with full regioselectivity and high stereoselectivity. In consequence, 3,4-trans-2-methyl-3-(3,4,5-trimethoxyphenyl)-4-halo-4-nitroisoxazolidines are forming as predominantly (or sole) products. Additionally, prognosis for the synthesized compounds to be potential ingredients of drugs is good.

6p tocectocec 26-05-2020 22 1   Download

Objectives of the thesis: Research to clarify the main chemical composition of two species of G. glomerulatum, G. hirsutum in Vietnam. Evaluation of toxic activity cells of isolated compounds to search for bioactive compounds, as a scientific basis for further research to create care products health for the community and contribute to explaining the curative effect of these species.

27p xacxuoc4321 09-07-2019 51 5   Download

The research objective of the dissertation is to research and apply enzyme technology to hydrolysis of plant glycoid compounds, creating higher activity products and developing green research in organic chemistry.

27p xacxuoc4321 09-07-2019 45 3   Download

The research objectives of the dissertation isolate and determine the structure of clean compounds from mondo grass root roots. Evaluate cytotoxic effects and anti-inflammatory activity based on the effect of inhibiting NO production of isolated compounds.

27p xacxuoc4321 11-07-2019 41 3   Download

Human interleukin-11 (hIL-11) is a pleiotropic cytokine that is involved in numerous biological activities such as hematopoiesis, osteoclastogenesis, neurogenesis and female fertility. IL-11 is obviously a key reagent to study the IL-11 receptors. However, conventional radio-iodination techni-ques lead to a loss of IL-11 bioactivity. Here, we report the construction and the production of a new recombinant human IL-11 (FPDIL-11). In this molecule, a speci®c phosphorylation site (RRASVA) has been introduced at the N-terminus of rhIL-11. ...

8p research12 29-04-2013 30 4   Download

Characterization of the peptide content of venoms has a number of poten-tial benefits for basic research, clinical diagnosis, development of new therapeutic agents, and production of antiserum. Here, we use a substrate-capture assay that employs a catalytically inactive mutant of thimet oligo-peptidase (EC 3.4.24.15; EP24.15) to identify novel bioactive peptides in Bothrops jararacussu venom.

13p media19 06-03-2013 45 5   Download

Cyclooxygenases (COXs) catalyze the rate-limiting step in the production of prostaglandins, bioactive compounds involved in processes such as fever and sensitivity to pain, and are the target of aspirin-like drugs. COX genes have been cloned from coral, tunicates and vertebrates, and in all the phyla where they are found, there are two genes encoding two COX isoenzymes; it is unclear whether these genes arose from an early single duplication event or from multiple independent duplications in evolution. The...

7p thulanh19 09-11-2011 33 3   Download