Biologic features

Glioblastoma is a malignant and aggressive type of central nevous system malignancy characterized by many distinct biological features including extensive hypoxia. Hypoxia in glioblatoma associates with complex signaling patterns including activation of several pathways such as MAPK, PI3K-AKT/mTOR and IL-6/JAK/STAT3 with the master regulator HIF-1, which in turn drive particular tumor behaviors determining, in the end, treatment outcomes and patients fate.

12p vishanshan 27-06-2024 2 1   Download

Nasopharyngeal adenoid cystic carcinoma (NACC) is a rare malignancy with special biological features. Controversies exist regarding the treatment approach and prognostic factors in the IMRT era. This study aimed to evaluate the long-term outcomes and management approaches in NACC.

9p vishanshan 27-06-2024 1 1   Download

Ebook "Galectins: Methods and protocols" is dedicated to examining salient features of galectin functions. Each chapter has been written by the world’s experts in the field and features clear protocols with notes that provide important considerations that will help you avoid common pitfalls when examining galectin biology.

505p dongmelo 27-05-2024 4 2   Download

Ebook "Handbook of Maize: Its biology" centers on the past, present and future of maize as a model for plant science research and crop improvement. The book includes brief, focused chapters from the foremost maize experts and features a succinct collection of informative images representing the maize germplasm collection.

583p ladongphongthanh1008 22-04-2024 6 4   Download

Ebook "Immunoformatics: Bioinformatic strategies for better understanding of immune function" is the first to feature thorough coverage of this new field. Immunoinformatics facilitates the understanding of immune function by modelling the interactions among immunological components. Biological research provides ever deeper insights into the complexity of living organisms while computer science provides an effective means to store and analyse large volumes of complex data.

271p tracanhphuonghoa1007 22-04-2024 2 1   Download

Ebook "RAS family GTPases" features chapters by leading investigators in the field that highlight the current state-of-the art in Ras biochemistry, structure and biology. This book is an excellent reference for students in the biomedical sciences and for investigators in the field.

403p tracanhphuonghoa1007 22-04-2024 1 1   Download

Ebook "Power laws, scale-free networks and genome biology" deals with crucial aspects of the theoretical foundations of systems biology, namely power law distributions and scale-free networks which have emerged as the hallmarks of biological organization in the post-genomic era. The chapters in the book not only describe the interesting mathematical properties of biological networks but moves beyond phenomenology, toward models of evolution capable of explaining the emergence of these features.

274p tracanhphuonghoa1007 22-04-2024 9 2   Download

Ebook "Carbohydrate-based interactions at the molecular and the cellular level" offers a clearly written and highly accessible account of two different aspects of carbohydrate chemistry. Carbohydrates are an essential component of life and have many important biological functions, but the details of how carbohydrates interact with other biomolecules to mediate biological signalling remain unclear. Firstly, this thesis details innovative methods to mine protein structural data to uncover new features of carbohydrate-based interactions.

216p tracanhphuonghoa1007 22-04-2024 4 3   Download

Ebook "CFTR and cystic fibrosis: From structure to function" is devoted to the CFTR protein and cystic fibrosis, and it provides an updated perspective of the genetic, functional and cellular processes involved in this conformational disorder. Starting with a historical perspective on cystic fibrosis and its clinical features, the author departs into an in-depth description of the biology of the CFTR protein, ending with a discussion on the latest approaches aimed at developing corrective therapies for cystic fibrosis.

70p tracanhphuonghoa1007 22-04-2024 3 2   Download

Cerebral amyloidosis, neuroinflammation, and tauopathy are key features of Alzheimer’s disease (AD), but interactions among these features remain poorly understood. Our previous multiscale molecular network models of AD revealed TYROBP as a key driver of an immune- and microglia-specific network that was robustly associated with AD pathophysiology.

20p vibransone 28-03-2024 3 2   Download

Ebook "Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexes" has led to a better understanding of the metal ion binding and active site structural features of the enzyme GpdQ. Daumann describes how she successfully immobilized phosphoesterase and related biomimetics on solid supports for potential applications in the area of bioremediation of organophosphate pesticides.

253p tudohanhtau1006 29-03-2024 4 1   Download

Ebook "Bone morphogenetic proteins: Systems biology regulators" focuses on the salient features of the biology of Bone Morphogenetic Proteins and the advances in our understanding of their structure and function and of downstream signaling, as well as their governance in systems biology from bone and dentin to kidney, cancer, diabetes, iron homeostasis and angiogenesis, including rare musculoskeletal disorders.

448p cotieubac1004 15-03-2024 3 0   Download

Ebook "Biology and management of unusual plasma cell dyscrasias" focuses on the non-myeloma plasma cell dyscrasias. A key resource for this group of diseases, the book features the latest in emerging knowledge and therapeutic developments, including novel therapies. Each disease-specific chapter discusses biology, disease course, and appropriate therapeutic interventions, covering plasma cell leukemia, plasmacytoma, POEMS Syndrome and Castleman's Disease, Waldenström macroglobulinemia, immunoglobin deposition disease, and cryoglobulinemic syndromes, among others.

207p cotieubac1004 15-03-2024 0 0   Download

Transcriptional classifcation has been used to stratify colorectal cancer (CRC) into molecular subtypes with distinct biological and clinical features. However, it is not clear whether such subtypes represent discrete, mutually exclusive entities or molecular/phenotypic states with potential overlap.

17p vicwell 29-02-2024 4 1   Download

Papillary thyroid carcinoma accounts for the most common type of thyroid cancer of well-differentiated type. Papillary thyroid carcinoma is featured by biologically low-grade and less aggressive tumors with a survival rate of 10 years in most of the diagnosed cases.

8p vitiki 30-01-2024 6 2   Download

Ebook "Genetics and genomics of Populus" provides an indepth description of the genetic and genomic tools and approaches for Populus, examines the biology that has been elucidated using genomics, and looks to the future of this unique model plant. This volume is designed to serve both experienced Populus researchers and newcomers to the field. Contributors to the volume are a blend of researchers, some who have spent most of their research career on Populus and others that have moved to Populus from other model systems.

388p tachieuhoa 28-01-2024 3 2   Download

Ebook The laboratory ferret includes content: Important biological features, husbandry, management, veterinary care, experimental methodology, resources and additional information.

123p muasambanhan04 14-01-2024 2 2   Download

Ebook "Edible insects in sustainable food systems" provides an important overview of the contributions of edible insects to ecological sustainability, livelihoods, nutrition and health, food culture and food systems around the world. While insect farming for both food and feed is rapidly increasing in popularity around the world, the role that wild insect species have played in the lives and societies of millions of people worldwide cannot be ignored.

468p lamquandat 28-12-2023 6 2   Download

Ebook "Plant chromatin dynamics: Methods and protocols" provides a comprehensive collection of protocols that can be used to study plant chromatin structure and composition. Chapters divided into three sections detail the profiling of chromatin features in relation to epigenetic regulation, investigate the interaction between chromatin modifications and gene regulation, and explore the 3D spatial organization of the chromatin inside the nucleus.

650p lucchinguyen 28-12-2023 6 3   Download

Ebook "The bifidobacteria and related organisms: Biology, taxonomy, applications" brings together authoritative reviews on all aspects of Bifidobacteria and related genera. Their place within the Phylum Actinobacteria is discussed first, and this is followed by descriptions of the genera Bifidobacterium, Alloscardovia, Aeriscardovia, Bombiscardovia, Gardnerella, Metascardovia, Parascardovia and Scardovia and the currently accredited species within those genera.

326p lucchinguyen 28-12-2023 4 2   Download