Biological age

In the era of targeted therapies, the influence of aging on cancer management varies from one patient to another. Assessing individual frailty using geriatric tools has its limitations, and is not appropriate for all patients especially the youngest one.

8p vikoch 27-06-2024 1 1   Download

In children, the central nervous system tumors are exceeded in incidence only by leukemia and are more common than any of the other malignancies of childhood. Childhood central nervous system tumors encompass a range of histologic varieties from the histologically benignappearing pilocytic astrocytoma to the extremely malignant-appearing glioblastoma multiforme and the undifferentiated primitive neuroectodermal tumors. Similarly, the biologic behavior of childhood brain tumors varies not only according to histology but also with location of the tumor and age.

518p vimeyers 29-05-2024 2 2   Download

The current understanding of autism spectrum disorder (ASD) as an alteration of neurodevelopment requires deepening in the causes that originate it. This study aims to investigate the relationship between the presence of ASD in subjects aged 2-22 years and some related biological factors (sex/gender, age, and body mass index).

10p viarnault 25-04-2024 1 1   Download

Ebook "Longevity genes: A blueprint for aging" describes the hunt for genes affecting complex traits using a high throughput technology, with adequate consideration for the selection of an appropriate population, applications of statistical genetics and computational biology, and most importantly, considering phenotype-genotype association studies. Longevity Genes provides coverage of not only established aspects of genetics and aging, but also new approaches and perceptions in this important area of research.

199p ladongphongthanh1008 22-04-2024 3 2   Download

Ebook "Neural stem cells in development, adulthood and disease" is the first to specifically target developing, adult and diseased neural stem cells. It explores recent advances in the understanding of neural stem cell biology along with strategies that use these cells to tackle neurological diseases and brain aging. Ten inclusive chapters discuss a wide range of topics including neurogenesis, neurodegeneration, demyelinating disease, mood regulation, and spinal cord regeneration, among others.

219p ladongphongthanh1008 22-04-2024 1 1   Download

Ebook "Eco-immunology: Evolutive aspects and future perspectives" represents a cutting-edge contribution giving an all-around perspective of eco-immunology today. Beside questions of the utmost importance for the whole community of immunologists, e.g, the intrinsic limits of immunological experiments performed at the bench on a limited number of selected models, the book covers several other facets of the eco-immunological approach, including host-parasite interactions, human aging and population immunology.

185p tracanhphuonghoa1007 22-04-2024 4 2   Download

DNA methylation changes with age. Chronological age predictors built from DNA methylation are termed ‘epigenetic clocks’. The deviation of predicted age from the actual age (‘age acceleration residual’, AAR) has been reported to be associated with death. However, it is currently unclear how a better prediction of chronological age affects such association.

11p vibransone 28-03-2024 6 2   Download

While clinical factors such as age, grade, stage, and histological subtype provide physicians with information about patient prognosis, genomic data can further improve these predictions. Previous studies have shown that germline variants in known cancer driver genes are predictive of patient outcome.

18p vibransone 28-03-2024 4 2   Download

This paper aims to evaluate the nature of halal risk management by focusing on the advent of online business. Globally, there is a growing trend of halal trading activities from inbound to outbound stages in a virtual marketplace utilising the advancement of online technology. With reference to MS 2400: 2010, an organization must establish a Halalan-Toyyiban Risk Management Plan (HTRMP) following the principles outlined in the standard. This means, beside Halal, the elements for Toyyib should also be considered during risk management, namely the physical, chemical and biological aspects.

6p longtimenosee06 27-03-2024 3 2   Download

Epigenetic alterations are associated with normal biological processes such as aging or differentiation. Changes in global epigenetic signatures, together with genetic alterations, are driving events in several diseases including cancer. Comparative studies of cancer and healthy tissues found alterations in patterns of DNA methylation, histone posttranslational modifications, and changes in chromatin accessibility.

12p vibransone 28-03-2024 7 2   Download

Ebook "Stem cell biology and regenerative medicine in ophthalmology" provides a comprehensive and engaging overview of the latest innovations in the field. Twelve chapters discuss the fastest growing areas in ophthalmological stem cell research, from disease modelling, drug screening and gene targeting to clinical genetics and regenerative treatments. Innovative results from stem cell research of the past decade are pointing the way toward practicable treatments for retinitis pigmentosa, age related macular degeneration, and Stargardt disease.

196p cotieubac1004 15-03-2024 4 0   Download

Ebook "Protein metabolism and homeostasis in aging (Advances in experimental medicine and biology, Volume 694)" provided of the current knowledge in the area, including protein synthesis, accuracy and repair, post-translational modifications, degradation and turnover, and how they define and influence aging. The chapters mainly focus on well-characterised factors and pathways, but new areas are also presented, where associations with aging are just being elucidated by current experimental data.

268p duongthandue0501 28-02-2024 1 1   Download

Hearing problems (HP) in adults are common and are associated with several comorbid conditions. Its prevalence increases with age, reflecting the cumulative effect of environmental factors and genetic predisposition. Although several risk loci have been already identified, HP biology and epidemiology are still insufciently investigated by large-scale genetic studies.

18p vicwell 29-02-2024 3 1   Download

Epigenetic clocks can track both chronological age (cAge) and biological age (bAge). The latter is typically defined by physiological biomarkers and risk of adverse health outcomes, including all-cause mortality. As cohort sample sizes increase, estimates of cAge and bAge become more precise. Here, we aim to develop accurate epigenetic predictors of cAge and bAge, whilst improving our understanding of their epigenomic architecture.

15p vicwell 29-02-2024 6 1   Download

Ebook "Systems biology of Parkinson’s disease" will be underpinned by new measurement techniques. This is particularly true of the pathology of Parkinson's Disease, where recent developments in brain imaging have offered new insights into the morphology of dopaminergic neurons that have profound implications for the special vulnerability and role of this class of neurons.

187p duongthandue0501 28-02-2024 4 1   Download

Ebook "Artemisinin and nitric oxide: Mechanisms and implications in disease and health" discusses both the beneficial and harmful aspects of NO in biology and medicine, and also introduces the emerging discovery of artemisinin in antitumor, antibacterial infection, anti-inflammation, and antiaging contexts. In 1992 nitric oxide (NO) was voted “Molecule of the Year” by Science magazine, and the discovery of its physiological roles has led to Nobel Prize-winning work in neuroscience, physiology and immunology.

137p nhanphanguyet 28-01-2024 4 2   Download

Women from Asian and western countries have vastly different ages of onset of breast cancer, with the disease tending to occur at an older age in the West. Through an investigation of the patterns of old-onset breast cancer (OBC) in Korean women, we aimed to identify the characteristics of Korean OBC and evaluate whether these patterns are changing in relation to increasing westernization.

15p vileonardodavinci 23-12-2023 4 3   Download

Part 2 book "Seafood science - Advances in chemistry, technology and applications" includes content: Anti aging and immunoenhancing properties of marine bioactive compounds; arsenic in seaweed - presence, bioavailability and speciation; application of bacterial fermentation in edible brown algae; production, handling and processing of seaweeds in indonesia; food applications of by products from the sea; mining products from shrimp processing waste and their biological activities;... and other contents.

335p muasambanhan01 13-12-2023 6 3   Download

Part 2 book "Introduction to horse biology" includes content: The respiratory system, the nervous system, the endocrine system, reproduction, disease causing organisms, genetics and heredity, teeth and estimating age.

110p oursky08 04-11-2023 7 3   Download

Part 2 book "Honeybees, foraging behavior, reproductive biology and diseases" includes content: Situational choices among alternative visual stimuliin honeybees and paper wasps when for aging, fuel for foraging - regulation of the crop content of foragers upon departing the hive; sex differences of dopamine control systems associated with reproduction in honeybees, roundtrip structure of the foraging honeybee (apis mellifera).

85p oursky08 04-11-2023 5 2   Download