Biological causes

Pancreatic cancer, predominantly characterized by ductal adenocarcinoma (PDAC) accounts for 90% of cases and is the fourth leading cause of cancer-related deaths globally. Its incidence is notably increasing. This poor prognosis is primarily due to late-stage diagnosis (approximately 70% to 80% of patients are diagnosed at an advanced stage), aggressive tumor biology, and low sensitivity to chemotherapy.

10p vikoch 27-06-2024 3 1   Download

This volume reviews the current state of research concerning bacterial virulence factors and the infection biology of Helicobacter pylori, which is the leading cause of peptic ulcers and gastric cancer worldwide. The chapters include cutting-edge findings on this fascinating microbe and discuss the general strategies of H. pylori infection and persistence, news on important H. pylori virulence factors, crosstalk with the microbiota, hot novel models and signaling mechanisms, risk factors of gastric disease and stomach cancer, and the impact of H. pylori infection on non-gastric diseases.

363p vimeyers 29-05-2024 2 2   Download

The current understanding of autism spectrum disorder (ASD) as an alteration of neurodevelopment requires deepening in the causes that originate it. This study aims to investigate the relationship between the presence of ASD in subjects aged 2-22 years and some related biological factors (sex/gender, age, and body mass index).

10p viarnault 25-04-2024 1 1   Download

Ebook "Malaria: Drugs, disease and post-genomic biology" despite rapid increases in knowledge, malaria continues to kill more than a million people each year and causes symptomatic disease in a further 300 million individuals. This volume brings some of the world's best investigators to describe recent advances in both the scientific and clinical aspects of malaria, and bridges between the two.

447p tracanhphuonghoa1007 22-04-2024 4 1   Download

Ebook "Oxidative stress in cancer biology and therapy" in order to stimulate the discussion of how the knowledge gained in the emerging field of oxidative stress in cancer biology can be utilized to more effectively design interventions to enhance therapeutic responses while causing fewer treatment limiting complications.

465p tracanhphuonghoa1007 22-04-2024 2 2   Download

Congenital heart disease (CHD) occurs in almost 1% of newborn children and is considered a multifactorial disorder. CHD may segregate in families due to significant contribution of genetic factors in the disease etiology. The aim of the study was to identify pathophysiological mechanisms in families segregating CHD.

13p vibransone 28-03-2024 4 2   Download

Left-sided lesions (LSLs) account for an important fraction of severe congenital cardiovascular malformations (CVMs). The genetic contributions to LSLs are complex, and the mutations that cause these malformations span several diverse biological signaling pathways: TGFB, NOTCH, SHH, and more.

10p vioraclene 31-03-2024 8 2   Download

Tax management is carried out by all companies, including the agricultural sector. In practice, the impact on financial performance caused by various problems relates to accounting policies of biological assets, transparency, accountability, responsibility, independence, fairness, and the size of the company. This study aims to prove empirically whether there is an influence of biological asset accounting policy implications, good corporate governance practices, and company size on tax management through financial performance in agricultural sector companies.

10p longtimenosee06 27-03-2024 6 2   Download

Ebook "Reelin glycoprotein: Structure, biology and roles in health and disease" is a serine protease with important roles in embryogenesis and during adult life. Reelin mutations or deficiency of the protein product could cause abnormal cortical development and reelin signaling impairment in brain. Reelin abnormalities in several neurospychiatric disorders, such as autism, schizophrenia, mood disorders and lissencephaly, may provide mechanistic explanations for etiologies of these disorders.

473p cotieubac1004 15-03-2024 2 0   Download

In ebook "Molecular biology" plant biology is considered from the perspective of plants and their surrounding environment, including both biotic and abiotic interactions. The intended audience is undergraduate students in the middle or final phases of their programs of study.

427p cotieubac1004 15-03-2024 5 0   Download

Epigenetic clocks can track both chronological age (cAge) and biological age (bAge). The latter is typically defined by physiological biomarkers and risk of adverse health outcomes, including all-cause mortality. As cohort sample sizes increase, estimates of cAge and bAge become more precise. Here, we aim to develop accurate epigenetic predictors of cAge and bAge, whilst improving our understanding of their epigenomic architecture.

15p vicwell 29-02-2024 6 1   Download

In ebook "Ecology and the environment (The plant sciences series)" plant biology is considered from the perspective of plants and their surrounding environment, including both biotic and abiotic interactions. The intended audience is undergraduate students in the middle or final phases of their programs of study.

675p manmanthanhla0201 26-02-2024 3 1   Download

Ebook "Systems biology: Functional strategies of living organisms (Second edition)" is an excellent introduction to systems biology, which has developed rapidly in recent years. It discusses the processes in living organisms in an integrated way, enabling the reader to understand the fundamental principles and cause-effect relationships in biology and biochemistry.

269p manmanthanhla0201 26-02-2024 6 1   Download

Ebook "Agrobacterium: From biology to biotechnology" continues with a description of how Agrobacterium is used as a tool in plant biotechnology. The next two chapters describe our knowledge of the Agrobacterium genome gained with the advent of genomics approaches and place Agrobacterium in the taxonomic context of related bacterial species. The main portion of the book, which comprises 11 chapters, provides a detailed review of virtually all molecular aspects of the genetic transformation process, including chemistry, biochemistry and molecular biology of host recognition and attachment,...

768p tachieuhoa 28-01-2024 6 2   Download

Ebook "Bacterial fish pathogens: Disease of farmed and wild fish" is a comprehensive discussion of the biological aspects of the bacteria which cause disease in farmed and wild fish. Since the 4th edition was published in 2007, there has been an upturn in the application of molecular approaches to taxonomy, diagnosis and vaccine development. New pathogens, e.g. Aeromonas schubertii, have been described.

678p tachieuhoa 28-01-2024 5 2   Download

Ebook "Comparative physiology of fasting, starvation, and food limitation" summarizes state of the art of starvation biology from the ecological causes of food limitation to the physiological and evolutionary consequences of prolonged fasting. It is written for an audience with an understanding of general principles in animal physiology, yet offers a level of analysis and interpretation that will engage seasoned scientists.

431p tachieuhoa 28-01-2024 3 2   Download

Ebook "Campylobacter jejuni: Methods and protocols" is often regarded as the one of the most common causes of bacterial gastroenteritis worldwide. The goal of this volume is to highlight key protocols for working with C. jejuni. In particular, chapters aim to highlight recent developments with regards to in vivo models for C. jejuni pathogenesis, different approaches to isolate Campylobacter, and a systems biology approach for studying the effect of all potential Campylobacter gene mutants.

276p lucchinguyen 28-12-2023 5 2   Download

Ebook "Macroevolution in deep time" includes cutting edge research in evolutionary biology that should serve as a starting point for conservation. ​The prerequisite to investigating the underlying causes behind mass extinction is a profound understanding of the evolutionary history of both living and dead species.

69p lucchinguyen 28-12-2023 8 2   Download

Part 1 book "Cancer biology" includes content: What is cancer; natural history - the life of a cancer; pathology - Defining a neoplasm; epidemiology - identifying causes for human cancers; oncogenes, tumour suppressor genes and viruses, chemical and radiation carcinogenesis; mutations, DNA repair and genetic instability.

146p muasambanhan02 25-12-2023 2 2   Download

DCLRE1B is a 5’-to-3’ exonuclease, which is involved in repairing ICL-related DNA damage. DCLRE1B has been reported to cause poor prognosis in a variety of cancers. Nonetheless, there is no research on DCLRE1B’s biological role in pan-cancer datasets. Thus, ascertaining the processes via which DCLRE1B modulates tumorigenesis was the goal of the extensive bioinformatics investigation of pan-cancer datasets in the present research.

14p vialfrednobel 23-12-2023 5 3   Download