Biological potential

In the aim of further research of the highly bioactive benzofuran and triazine derivatives, the synthesis of 1,2,4-triazine derivatives bearing the benzofuran moiety has been undertaken. Using a simple and convenient method, a three steps synthesis of novel functionalized 1,2,4-triazine derivatives from readily available starting materials has been described.

6p viprimi 16-12-2024 0 0   Download

The project's main objectives were to analyse the data obtained during geological exploration and use it to model and predict biological patterns in order to answer the main research questions: 1) Is there a statistical relationship between the environmental parameters and the benthic community composition and morphospecies observed? 2) Can predictive models be developed from this relationship? In achieving these main objectives, the project also developed recommendations for methods that could be applied during geological exploration voyages to maximise the potential use of data collected.

206p runthenight04 02-02-2023 6 2   Download

Immediate objective: Identification of the seaweed species composition and its distribution characteristics; evaluation of economic potential seaweed species to establish and manage its exploitation and conservation areas in Phu Yen province.

25p beloveinhouse01 15-08-2021 30 3   Download

Research is conducted on the Ban Pig model with goals: To determine the potential of Ban Pig's oocyte exploitation; to determine cultivate conditions of the oocyte mature in Ban Pig; success in establishing create Pig’s embryo system through in vitro fertilization (IVF) and cloning (C).

28p beloveinhouse01 15-08-2021 14 3   Download

General objectives: Creating of attenuated mutant Vibrio parahaemolyticus strains causing immune response for fish to develop production of vaccines against nephrotic and hepatic necrosis disease for some marine fish.

27p tunelove 10-06-2021 13 4   Download

Objectives: This study aims to evaluate the species diversity, distribution pattern and phylogenetic relationships of the genus Megophrys in Vietnam.

28p thebadguys 08-06-2021 15 3   Download

The objectives of the thesis: The objectives of this study are to investigate the main chemical compositions of Euphorbia hirta L. to search for chemical constituents in relation to biological activities, contributing to further studies to create products for application in the aquarculture industry in particular and for life in general.

31p extraenglish 24-05-2021 34 3   Download

The research objectives of the thesis: Forecast the potential risks of Cu2+, Pb2+ residues on the reproduction and development of oysters Crassostrea gigas on Saigon - Dong Nai estuary.

24p extraenglish 24-05-2021 15 1   Download

The objectives of this study are to investigate the main chemical compositions of Euphorbia hirta L. to search for chemical constituents in relation to biological activities, contributing to further studies to create products for application in the aquarculture industry in particular and for life in general.

31p capheviahe27 23-02-2021 28 4   Download

The objectives of the thesis: Study on chemical constituents of two species Markhamia stipulata var. canaense V.S. Dang and Stereospermum binhchaunesis V.S. Dang; evaluation of biological activities of isolated compounds to find potential compounds.

27p capheviahe27 23-02-2021 15 3   Download

The objectives of the thesis: Study on chemical constituents of three Antidesma species including A. acidum, A. ghaesembilla, and A. hainanensis growing in Vietnam; evaluation of biological activities of isolated metabolites to find potential compounds.

27p capheviahe27 23-02-2021 29 4   Download

Aims of the study: Assess the composition and distribution of Amorphophallus genus (Amorphophallus spp.) contains glucomannan in some northern provinces in Vietnam; choosing the Amorphophallus species that has high level of glucomannan and developing potential for reproduction and growing in some norther provinces in Vietnam; testing the reproduction and growing of the candidate species in some northern provinces in Vietnam.

26p capheviahe27 23-02-2021 16 4   Download

The genus Litsea Lam. (Lauraceae) and Lepisanthes Blume (Sapindaceae) are wildly distributed in Vietnam, especially in the mountainous areas. The reports in the literatures indicated that these two genus contain many constituents with interesting structures and potential biological activities. In order to find interesting substances for development of new pharmaceutical ingredients or functional food products we would like to conduct the resarch thesis ‘‘Study on Chemical constituents and biological activities of Litsea glutinosa (Lour.) Rob. (Lauraceae) and Lepisanthes rubiginosa (Roxb.

26p xacxuoc4321 11-07-2019 30 6   Download

The aims of the dissertation are: Extracting and determining the structure of organic compounds of four plant species with potential for insecticide and fungal diseases. Isolating endogenous fungi from plant samples, extracting and determining the structure of component organic compounds. Testing of insecticidal and fungal activity of extracts and component organic compounds.

35p xacxuoc4321 08-07-2019 33 3   Download

Thesis study of the composition of the parasitic nematodes in marine fishes in the off Vietnam is urgently needed. The survey’s results are not only provide the information about the fauna of fish’s nematoda, the relation between hosts-parasites, but also assess the the potential risks for human consumption.

27p xacxuoc4321 08-07-2019 41 6   Download

In a previous study, the S100A8/A9 protein, a Ca2+- and arachidonic acid-binding protein, abundant in neutrophil cytosol, was found to potentiate the activation of the redox component of the O2– generating oxidase in neutrophils, namely the membrane-bound flavocytochrome b, by the cytosolic phox proteins p67phox, p47phox and Rac ` (Doussiere J., Bouzidi F. and Vignais P.V. (2001) Biochem. Biophys. Res. Commun. 285, 1317–1320). This led us to check by immunoprecipitation and protein fractionation whether the cytosolic phox proteins could bind to S100A8/A9.

10p system191 01-06-2013 30 4   Download

In the biosynthesis of the antiarrhythmic alkaloid ajmaline, polyneuridine aldehyde esterase (PNAE) catalyses a central reaction by transforming polyneuridine aldehyde into epivellosimine, which is the immediate precursor for the synthesis of the ajmalane skeleton. The PNAE cDNA was previously heterologously expressed in E. coli. Sequence alignments indicated that PNAE has a 43% identity to a hydroxynitrile lyase from Hevea brasiliensis, which is a member of the a/b hydrolase superfamily. The catalytic triad, which is typical for this family, is conserved.

8p system191 01-06-2013 36 4   Download

Departamento de Bioquı´mica y Biologı´a Molecular y Celular, Facultad de Ciencias, Universidad de Zaragoza, Spain; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota, USA Reduction potential determinations of K75E, E139K and E301A ferredoxin-NADP+ reductases provide valuable information concerning the factors that contribute to tune the flavin reduction potential. Thus, while E139 is not involved in such modulation, the K75 side-chain tunes the flavin potential by creating a defined environment that modulates the FAD conformation. ...

6p system191 01-06-2013 36 4   Download

The aim of this study was to increase the stability of the thermolabile (ba)8-barrel enzyme indoleglycerol phosphate synthase from Escherichia coli by the introduction of disulfide bridges. For the design of such variants, we selected two out of 12 candidates, in which newly introduced cysteines potentially form optimal disulfide bonds. These variants avoid short-range connections, substitutions near catalytic residues, and crosslinks between the new and the three parental cysteines.

9p research12 01-06-2013 38 4   Download

Thecaa3-oxidase from Thermus thermophilushas been studied with a combined electrochemical, UV/VIS and Fourier-transform infrared (FT-IR) spectroscopic approach. In this oxidase the electron donor, cytochromec, is covalently bound to subunit II of the cytochrome c oxidase. Oxidative electrochemical redox titrations in the visible spectral range yielded a midpoint potential of )0.01 ± 0.01 V (vs. Ag/AgCl/3MKCl, 0.218 V vs. SHE¢) for the hemec.

9p research12 29-04-2013 49 3   Download