Biological systems

Glioblastoma is a malignant and aggressive type of central nevous system malignancy characterized by many distinct biological features including extensive hypoxia. Hypoxia in glioblatoma associates with complex signaling patterns including activation of several pathways such as MAPK, PI3K-AKT/mTOR and IL-6/JAK/STAT3 with the master regulator HIF-1, which in turn drive particular tumor behaviors determining, in the end, treatment outcomes and patients fate.

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Endometrial cancer is one of the most common types of cancer that affects women’s reproductive system. The risk of endometrial cancer is associated with biologic, behavioral and social determinants of health (SDOH).

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Despite the known association between healthy lifestyles and reduced risk of breast cancer, it remains unclear whether systemic inflammation, as a consequence of unhealthy lifestyles, may mediate the association.

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In children, the central nervous system tumors are exceeded in incidence only by leukemia and are more common than any of the other malignancies of childhood. Childhood central nervous system tumors encompass a range of histologic varieties from the histologically benignappearing pilocytic astrocytoma to the extremely malignant-appearing glioblastoma multiforme and the undifferentiated primitive neuroectodermal tumors. Similarly, the biologic behavior of childhood brain tumors varies not only according to histology but also with location of the tumor and age.

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The general aim of these advanced seminars is to bring together European Neurosurgeons interested or involved in research work, either clinically, experimentally or both, in a given field in order to achieve in-depth informal discussions not possible in the more conventional large congress. In particular, these advanced seminars seek to provide high level teaching by experienced basic scientists, to provide "state of the art" assessment of the subject and to highlight areas of controversy that may be suitable for future research.

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This book develops the mathematical tools essential for students in the life sciences to describe interacting systems and predict their behavior. From predator-prey populations in an ecosystem, to hormone regulation within the body, the natural world abounds in dynamical systems that affect us profoundly.

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This Volume presents protocols for systems and synthetic biology applications in the field of hydrocarbon and lipid microbiology. It complements another Volume that describes generic protocols for wet experimental and computer-based systems and synthetic biology studies.

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The encyclopedia provides valuable reference material for those working in the field who wish to know more about a topic outside their area of expertise, as well as providing an authoritative reference source for students and researchers. Undergraduate students should find it a useful source of material, as will teachers and lecturers.

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Ebook "Resilient Asia: Fusion of traditional and modern systems for a sustainable future" summarizes three years of extensive research conducted in Sri Lanka, Indonesia and Vietnam as part of the CECAR – Asia project, which was intended to enhance resilience to climate and ecosystem changes by developing mosaic systems to strengthen resilience of bio-production systems through the integration of large-scale modern agriculture systems with traditional, decentralized small-scale systems.

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Ebook "Mycobacteria protocols (Second edition)" updates and refines the methods of the well-received first edition while adding newly developed methods culled from the most cutting-edge research in the field. Ranging from the basics of sub-cellular fractionation to advanced methods using specialized growth conditions and whole genome, transcriptome and proteome analysis, the chapters conform to the Methods in Molecular Biology™ series format, providing step-by-step laboratory protocols, lists of necessary materials and reagents, and tips on troubleshooting and avoiding known pitfalls.

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Ebook "Systems medicine" guides readers through the field of systems medicine by defining the terminology, and describing how established computational methods form bioinformatics and systems biology can be taken forward to an integrative systems medicine approach. Chapters provide an outlook on the role that systems medicine may or should play in various medical fields, and describe different facets of the systems medicine approach in action.

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Lecture Artificial intelligence: Artificial neural network. This lecture provides students with content including: computing systems inspired by biological neural networks; consists of several processing elements that receive inputs and deliver outputs; "learn" to perform tasks by considering examples; be able to model nonlinear processes;... Please refer to the detailed content of the lecture!

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In this study, we synthesized magnetic activated carbon (MAC) derived from Litsea glutinosa seeds, which was applied to eliminate methylene blue and nickel ions in the aeration tank of the biological treatment system. Structural characteristics and adsorption properties of MAC were studied. The obtained results revealed that the removal efficiency of these pollutants significantly improved as a combination of MAC and activated sludge, especially in the case of nickel ions removal.

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Ebook "Current topics in innate immunity II" compiles the latest advances in this rapidly evolving field as presented by eminent scientists at the 7th International Aegean Conference on Innate Immunity in Rhodes, Greece. It includes topics related to the biology and function of Toll-like and other pattern-recognition receptors, complement and its crosstalk with other physiological systems, inflammatory mechanisms and diseases, natural killer cells, and the cooperative interplay between innate and adaptive immune cells.

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Ebook "Systems biology of tuberculosis" starts with a general introduction into the relevance of systems biology for understanding tuberculosis. This will be followed by several chapters which describe the application of systems biology to various aspects of the study of the pathogen, Mycobacterium tuberculosis, and its interaction with the host. The book provides the reader with an account of how the new science of systems biology is providing novel insights into the ancient scourge of tuberculosis.

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Ebook "Genetics meets metabolomics: From experiment to systems biology" is written by leading researchers in the fields about the intersection of genetics and metabolomics which can lead to more comprehensive studies of inborn variation of metabolism.

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Ebook "Forkhead transcription factors: Vital elements in biology and medicine" provides a unique platform for the presentation of novel work and new insights into the vital role that forkhead transcription factors play in multiple systems throughout the body. Leading international authorities provide their knowledge and insights to offer a novel perspective for translational medicine that highlights the role of forkhead genes and proteins that may have the greatest impact for the development of new strategies for a broad array of disorders.

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Ebook "Biology of the fungal cell: Volume VIII (2nd edition)" provides readers with contents including: the endomembrane system of the fungal cell; motile tubular vacuole systems; the fungal woronin body; a molecular and genomic view of the fungal cell wall; the cytoskeleton and polarized growth of filamentous fungi; polarised growth in fungi; signal transduction and morphogenesis in candida albicans;...

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Ebook "Biophotonics and coherent systems in biology" provides readers with contents including: from mitogenetic rays to biophotons; photon sucking as an essential principle of biological regulation; quantum squeezed state description of spectral decompositions of a biophoton signal and the possibility of remote intervention; biological structure as a converter of coherent radiation;...

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Ebook "Functional coherence of molecular networks in bioinformatics" will provide a detailed review of existing knowledge on the functional characterization of biological networks. In 15 chapters authored by an international group of prolific systems biology and bioinformatics researchers, it will organize, conceptualize, and summarize the existing core of research results and computational methods on understanding biological function from a network perspective.

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