Biologics manufacturing

Ebook "Mammalian cell cultures for biologics manufacturing" are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors.

262p nhanphanguyet 28-01-2024 4 2   Download

As known, due to many advantages, X-ray machines have been widely applied in society-economy such as medicine, industry, customs, biology, etc. Depending on an aim of use, they have been manufactured with different structures on generating tube, range of high voltage, current of generating tube, anode target, additional and inherent filters, collimator for X-ray beam, etc.

7p vicedric 08-02-2023 5 4   Download

Panax ginseng is one of the most important medicinal plants in Asian countries such as Vietnam, South Korea, India and China. The ginseng root is normally harvested after four or six years of growth, which has been commonly used for manufacturing health supplements.

7p vineville 08-02-2023 3 1   Download

Various high-throughput systems and strategies are employed by the biopharmaceutical industry for early to late-stage process development for biologics manufacturing. The associated increases to experiment productivity and reduction in material consumption makes high throughput tools integral for bioprocess development.

11p vironald 15-12-2022 6 2   Download

Cadmium (Cd)-containing chemicals can cause serious damage to biological systems. In animals and plants, Cd exposure can lead to metabolic disorders or death. However, for the most part the effects of Cd on specific biological processes are not known. DNA methylation is an important mechanism for the regulation of gene expression.

13p visilicon2711 20-08-2021 9 1   Download

This dissertation focuses on establishing the process of manufacturing bimetallic Fe / Cu internal electrolysis nanomaterial, thereby studying some characteristics correlation between corrosive line and TNT decomposition kinetics and time. Setting and optimizing the internal electrolysis process by bimetal Fe / Cu nanomaterials combined with biological method A2O-MBBR (moving bed Biological reactor) to treat TNT wastewater at laboratory scale and Pilot scale at the scene.

27p larachdumlanat129 20-01-2021 17 2   Download

Bamboo is a sustainable and environmental friendly material that has the potential to improve the global decline of natural resources. Bamboo is one of the popular flora in Southeast of Asia, it is also traditional plants that grow abundantly in Vietnamese villages from north to south. Its ability can replace some kinds of wood in decoration and household goods. Bamboo grow up rapidly and can be harvested within 3 to 5 years of planting, in the meanwhile the harvesting time of other hardwood trees must be from 8 to 10 years or longer.

6p trinhthamhodang9 04-12-2020 12 2   Download

Petrochemical Industry manufacturing petrochemical product-generate waste containing organic compounds. As the toxicity level of most of these compounds is high, there is an increasing demand for remediation of such sites that involves removal of the offending compounds. Bioremediation uses living systems or biological products to biodegrade waste, with the objective being reduction of waste to chemical forms that can be assimilated into natural cycles. In the present study, the use of micro-organism for bioremediation has been carried out.

7p nguaconbaynhay6 24-06-2020 14 0   Download

The extensive use of fascinating colorful dyes during textile manufacturing indirectly causes severe environmental problem. These dyes exert toxic effects on terrestrial and aquatic life forms, imparting photosynthesis and other metabolic processes. Color is an escalating problem in industrial wastewater. Hence, there is a pressing need to eradicate this contaminant for a sustainable environment. This investigation was directed to isolate and characterized potential bacteria which can efficiently decolorize common recalcitrant textile dye Yellow CRG.

10p nguaconbaynhay6 24-06-2020 9 0   Download

Starch from maize kernels has diverse applications in human and animal diets and in industry and manufacturing. To meet the demands of these applications, starch quantity and quality need improvement, which requires a clear understanding of the functional mechanisms involved in starch biosynthesis and accumulation.

12p vihashirama2711 21-05-2020 16 1   Download

For assessment of biosimilarity, the US Food and Drug Administration (FDA) recommends a stepwise approach for obtaining the totality-of-the-evidence for demonstrating biosimilarity between a proposed biosimilar product and an innovative (reference) biological product. The stepwise approach starts with analytical studies for functional and structural characterization at various stages of manufacturing process of the proposed biosimilar product. Analytical similarity assessment involves identification of critical quality attributes (CQAs) that are relevant to clinical outcomes.

8p caothientrangnguyen 09-05-2020 16 0   Download

Antimicrobial peptides have become important candidates as new antibiotics against resistant bacterial strains. However, the major industrial manufacture of antimicrobial peptides is chemical synthesis with high costs and in relatively small scale.

10p viuchiha2711 21-04-2020 6 0   Download

Natural products are structurally and biologically interesting metabolites, but they have been isolated in minute amounts. The syntheses of such natural products help in obtaining them in bulk amounts. The recognition of microbial biotransformation as important manufacturing tool has increased in chemical and pharmaceutical industries. In recent years, microbial transformation is increasing significantly from limited interest into highly active area in green chemistry including preparation of pharmaceutical products.

17p trinhthamhodang1 16-11-2019 14 1   Download

Exosomes represent an important mode of intercellular communication and play key roles in many physiological and pathological processes. Exosomes have hitherto exhibited their capacity to modulate biological activities through their carrying of functional molecules such as proteins, lipids, and genetic materials. In the current study, we investigated exosomes released by mature dendritic cells (mDCs) and umbilical cord-derived mesenchymal stem cells (UCMSCs) under Good Manufacturing Practice (GMP) conditions. Ultracentrifugation was used to isolate and purify the exosomes.

7p caygaocaolon1 13-11-2019 18 1   Download

This is a comprehensive source of information on the application of ion chromatography (IC) in the analysis of pharmaceutical drugs and biologicals. This book, with contributors from academia, pharma, the biotech industry, and instrument manufacturing, presents the different perspectives, experience, and expertise of the thought leaders of IC in a comprehensive manner. It explores potential IC applications in different aspects of product development and quality control testing.

260p phongluu9x 22-10-2014 67 4   Download

Nikolas Kompridis has also written about the dangers of new technology, such as genetic engineering, nanotechnology, synthetic biology and robotics. He warns that these technologies introduce unprecedented new challenges to human beings, including the possibility of the permanent alteration of our biological nature. These concerns are shared by other philosophers, scientists and public intellectuals who have written about similar issues (e.g. Francis Fukuyama, Jürgen Habermas, William Joy, and Michael Sandel).[50]...

32p nt18104 21-05-2013 40 3   Download

Cement manufacturing is an energy-intensive process due to the high temperatures required in the kilns for clinkerization. The use of alternative fuels to replace conventional fuels, in particular coal, is a widespread practice and can contribute to improving the global warming impact and total environmental footprint of the cement industry.

89p loixinloi 08-05-2013 62 6   Download

Supplementing aids can be paid for liquid skimmed milk used in the manufacture of casein and in feeding. They can also be approved for SMP employed in feedstuff, making it more competitive compared to vegetable proteins. The subsidy rate granted takes into account market conditions, e.g. it was reduced to zero in October 2006, as EU market prices for milk protein became exceptionally high. In general, comparable aids are provided for the use of cream, butter and concentrated butter.

74p conduongdinhmenh 07-05-2013 29 3   Download

Food Science and Technology is a multi-disciplinary field that applies fundamental scientific principles to the research, development, manufacture, packaging, storage, and marketing of food products. It is a discipline in which biology, chemistry, engineering, microbiology, biochemistry, toxicology, management, and other basic and applied sciences are used to study the nature of foods, the causes of their deterioration, and the principles underlying food processing.

20p conduongdinhmenh 07-05-2013 66 7   Download

Generally, a process is defined as a sequence of events that transforms the biological materials of food products, via biochemical changes, into stable forms with added value. This can create new products or modify existing ones. Process design refers to the design of food processes and manufacturing methods, while plant design refers to the design of the whole processing plant. The processing of food is no longer as simple or straightforward as in the past. Food process design is an interdisciplinary science that is highly regarded by the food industry.

1533p namde04 02-05-2013 167 48   Download