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Bone marrow biopsy
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Part 2 book "Crow and Walshaw's manual of clinical procedures in dogs, cats, rabbits and rodents" includes content: Skin preparation, intubation, gastric lavage, transtracheal wash, centesis, peritoneal catheterization and lavage, needle biopsy of masses and viscera, urohydropropulsion, prostatic massage washing, semen collection and artificial insemination, vaginal examination and specimen collection, bone marrow aspiration and biopsy, cerebrospinal fluid collection,...and other contents.
185p
oursky08
06-11-2023
5
4
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Plasmacytomas are rare extramedullary plasma cell neoplasms that present in bone and/or soft tissue. Diagnosis can require a variety of laboratory approaches such as serum protein electrophoresis, bone marrow biopsy, Bence Jones protein assays, and imaging.
4p
viintuit
26-09-2023
0
0
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An elderly 72-year-old man presented with anemia, thrombocytopenia, monocytosis, splenomegaly and lymphadenopathy. Bone marrow biopsy was consistent with mast cell neoplasm with positive CD117, CD25, CD34 myeloblasts and polymerase chain reaction (PCR) revealed mutation of D816V. He developed bilateral femoral neck fractures and biopsy confirmed that he has systemic mastocytosis (SM).
3p
viintuit
26-09-2023
4
0
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The patient underwent bone marrow biopsy showing hypocellular marrow with erythroid-dominant, dysplastic hematopoiesis. A thorough panel of investigations to rule out secondary causes led to the diagnosis of aplastic anemia, for which the patient is currently being managed with oral ciclosporin plus eltrombopagbridging therapy, plus counselling for the potential requirement for stem cell transplant.
3p
viintuit
26-09-2023
5
0
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To investigate the feasibility, safety, and clinical application value of single-photon emission computed tomography/computed tomography (SPECT/CT)-guided bone marrow biopsy (BMB) in breast cancer (BC) patients with suspected bone metastases (BM) and compare its diagnostic performance for detection of BM with SPECT/CT.
9p
visusanwojcicki
28-06-2022
12
2
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The unicameral bone cyst (UBC) is a kind of benign tumor whose clinical treatments and efficacy are controversial. The purpose of this study was to evaluate the efficacy of the elastic stable intramedullary nail (ESIN), the injection of autologous bone marrow (ABM), and the combination of ESIN and ABM in the treatment of bone cyst in children.
7p
vivermont2711
28-01-2021
11
2
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Liver biopsies in pediatric hematopoietic stem cell transplantation (HSCT) patients are as and effective when performed at bedside in the Bone Marrow Transplant Unit (BMTU) than in the Day Surgery Unit (DSU), with better patient compliance and lower emotional distress for these children.
8p
vimale2711
25-08-2020
25
2
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To investigate whether PET/CT-guided bone marrow biopsy adds complementary information for evaluation of bone marrow involvement (BMI) in newly diagnosed lymphomas.
11p
viputrajaya2711
22-06-2020
8
0
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In under-resourced hematology laboratories there is usually a missing step in the battery of required investigations. Moreover, when some of the advanced diagnostic instruments can be found then the problem of chronic inadequate and irregular supply of kits and services would supervene.
222p
ti_du_hoang
10-08-2012
38
6
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Chronic lymphocytic leukemia. The peripheral white blood cell count is high due to increased numbers of small, well-differentiated, normal-appearing lymphocytes. The leukemia lymphocytes are fragile, and substantial numbers of broken, smudged cells are usually also present on the blood smear. If the primary presentation is lymphadenopathy and a lymph node biopsy is performed, pathologists usually have little difficulty in making the diagnosis of small lymphocytic lymphoma based on morphologic findings and immunophenotype.
6p
thanhongan
07-12-2010
72
2
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Pathophysiology Bone marrow failure results from severe damage to the hematopoietic cell compartment. In aplastic anemia, replacement of the bone marrow by fat is apparent in the morphology of the biopsy specimen (Fig. 102-1) and MRI of the spine. Cells bearing the CD34 antigen, a marker of early hematopoietic cells, are greatly diminished, and in functional studies, committed and primitive progenitor cells are virtually absent; in vitro assays have suggested that the stem cell pool is reduced to ≤1% of normal in severe disease at the time of presentation. Figure 102-1 A.
5p
thanhongan
07-12-2010
72
5
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Bone Marrow The bone marrow is usually readily aspirated but dilute on smear, and the fatty biopsy specimen may be grossly pale on withdrawal; a "dry tap" instead suggests fibrosis or myelophthisis.
5p
thanhongan
07-12-2010
74
4
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TRUS is the imaging technique most frequently used to assess the primary tumor, but its chief use is directing prostate biopsies, not staging. No TRUS finding consistently indicates cancer with certainty. CT lacks sensitivity and specificity to detect extraprostatic extension and is inferior to MRI in visualization of lymph nodes. In general, MRI performed with an endorectal coil is superior to CT to detect cancer in the prostate and to assess local disease extent.
5p
konheokonmummim
03-12-2010
114
5
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Lymphomas Lymphoma in the small bowel may be primary or secondary. A diagnosis of a primary intestinal lymphoma requires histologic confirmation in a clinical setting in which palpable adenopathy and hepatosplenomegaly are absent and no evidence of lymphoma is seen on chest radiograph, CT scan, or peripheral blood smear or on bone marrow aspiration and biopsy. Symptoms referable to the small bowel are present, usually accompanied by an anatomically discernible lesion.
5p
konheokonmummim
03-12-2010
56
2
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Staging of Small Cell Lung Cancer Pretreatment staging for patients with SCLC includes the initial general lung cancer evaluation with chest and abdominal CT scans (because of the high frequency of hepatic and adrenal involvement) as well as fiberoptic bronchoscopy with washings and biopsies to determine the tumor extent before therapy; brain CT scan (10% of patients have metastases); and radionuclide scans (bone) if symptoms or other findings suggest disease involvement in these areas.
7p
konheokonmummim
03-12-2010
105
7
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Bone Marrow Examination A bone marrow aspirate and smear or a needle biopsy may be useful in the evaluation of some patients with anemia. In patients with hypoproliferative anemia and normal iron status, a bone marrow is indicated. Marrow examination can diagnose primary marrow disorders such as myelofibrosis, a red cell maturation defect, or an infiltrative disease (Figs. 58-14, 58-15, and 58-16). The increase or decrease of one cell lineage (myeloid vs.
5p
konheokonmummim
03-12-2010
76
4
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