![](images/graphics/blank.gif)
Bone tissue engineering
-
This work aimed to introduce nanosized SiO2 into the CS matrix to produce three-dimensional (3D) scaffolds by solvent casting combined with salt leaching using NaCl as a porogen agent. The amount of the porogen to polymer was varied to produce 3D CS/SiO2 scaffolds with suitable pore sizes and porosity.
7p
dianmotminh02
03-05-2024
2
1
Download
-
The purpose of this study was to create an animal model of a mandibular alveolar bone defect without compromising the animal’s well-being. Materials and methods: A total of 24 New Zealand white rabbits underwent surgery to create mandibular alveolar bone defects. The animals were sacrificed at 2, 4, 6, 8, 10, and 12 weeks post-surgery.
10p
vioraclene
31-03-2024
5
2
Download
-
A novel polycaprolactonee zeolite nanocomposite Y (PCL - Zeol) scaffold was fabricated as a carrier for sustained release of cisplatin (Cis) for bone cancer treatment. In this regard, after synthesis of Zeol with a proper morphological uniformity, Cis was loaded with a high loading capacity into the cavities of Zeol nanoparticles.
11p
viberbers
09-08-2023
4
2
Download
-
In the quest to increase the quality of life and life expectancy, there is a great demand to develop advanced medical devices capable of facing current health challenges. Santa Barbara Amorphous (SBA-15) mesoporous silica has been demonstrated to be a remarkable option for a variety of biomedical applications, from tissue engineering to drug delivery, due to its unique hierarchical porous structure.
12p
vironald
15-12-2022
4
2
Download
-
Fourier Transformed Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM) coupled with Energy Dispersive X-ray Spectroscopy (EDS) were used for the ‘‘in vitro’’ evaluation of the bioactivity. The obtained results confirmed that the ceramic powder can be used as biomaterial for bone tissue engineering due to its high bioactivity expressed by the rapid formation of a biological carbonated hydroxyapatite layer on its surface after ‘‘in vitro’’ assay.
4p
vijaguar
16-11-2022
6
2
Download
-
In this article, chitosan/biphasic calcium phosphate (CS/BCP) nanofibers were prepared by electrospinning. From the culture of osteogenic cells, the biocompatibility of CS/BCP nanofibrous substrates was identified and increased by the photocrosslinking.
7p
visherylsandber
04-07-2022
9
2
Download
-
In this study, a fibrous bone tissue engineering scaffold was produced using poly(lactic-co-glycolic acid) (PLGA). Different concentrations (20%, 25%, and 30%) of PLGA (PLA:PGA 75:25) (Mw = 66,000–107,000) were wet spun using coagulation baths composed of different ratios (75:25, 60:40, 50:50) of isopropanol and distilled water. Scanning electron microscopy (SEM) and in vitro degradation studies were performed to characterize the fibrous PLGA scaffolds.
11p
thiencuuchu
27-11-2021
5
1
Download
-
In this study, a hydroxyapatite (HA) based scaffold was used together with human adipose stem cells (hASCs), human bone marrow stem cells (hBMSCs) and gingival epithelial cells to mimic human tooth dentin-pulp-enamel tissue complexes and model an immature tooth at the late bell stage in vitro. Characteristics of the scaffold were determined via SEM, FTIR, pore size and density measurements. Changes in gene expression, protein secretions and tissue histology resulting from cross-interactions of different dental tissues grown in the system were shown.
13p
thiencuuchu
27-11-2021
10
1
Download
-
Tissue engineering approaches for reconstruction of large bone defects are still technically immature, especially in regard to sufficient blood supply. Therefore, the aim of the present study was to investigate the influence of osteogenic stimulation and treatment with VEGF on new bone formation and neovascularization in hMSC-loaded cancellous bone scaffolds in vivo.
10p
viannito2711
20-04-2021
6
1
Download
-
Development of a pre-vascularized tissue-engineered construct with intrinsic vascular system for cell growth and tissue formation still faces many difficulties due to the complexity of the vascular network of natural bone tissue.
14p
vianrose2711
26-04-2021
15
2
Download
-
The study aimed to evaluate the combined effect of Pulsed Electromagnetic Field (PEMF) biophysical stimulation and bone marrow concentrate (BMC) in osteochondral defect healing in comparison to the treatment with scaffold alone.
8p
vioregon2711
22-02-2021
10
2
Download
-
New tissue engineering strategies for bone regeneration need to be investigated in a relevant preclinical large animal model before making the translation into human patients. Therefore, our interdisciplinary group established a simplified large animal screening model for intramembranous bone defect regeneration in cancellous and cortical bone.
12p
vioregon2711
22-02-2021
4
2
Download
-
To evaluate synchrotron radiation-based Fourier transform infrared microspectroscopy (SR-FTIR) as a tool for quantitative mapping of the content and distribution of the extracellular matrix in decellularized fibrocartilage bioscaffolds, and to provide a new platform for quantitatively characterizing bioscaffolds for tissue engineering.
8p
vitennessee2711
01-02-2021
11
1
Download
-
In severe injuries with loss of tendon substance a tendon graft or a synthetic substitute is usually used to restore functional length. This is usually associated with donor site morbidity, host tissue reactions and lack of remodelling of the synthetic substitutes, which may result in suboptimal outcome.
13p
vitennessee2711
02-02-2021
10
2
Download
-
Modifications to advanced Core decompression for treatment of Avascular necrosis of the femoral head
“Advanced Core Decompression” (ACD) is a new technique for treatment of osteonecrosis of the femoral head (ONFH) that includes removal of the necrotic tissue using a percutaneous expandable reamer followed by refilling of the drill hole and the defect with an injectable, hard-setting, composite calcium sulphate (CaSO4)-calcium phosphate (CaPO4) bone graft substitute.
8p
vitennessee2711
02-02-2021
12
2
Download
-
Different substances are combined to compensate for each other’s drawbacks and create an appropriate biomaterial. A novel Polyvinyl alcohol (PVA)/chitosan (CS) porous hydrogel was designed and applied to the treatment of osteochondral defects.
12p
vivermont2711
28-01-2021
12
1
Download
-
While multiple in vitro studies examined mesenchymal stromal cells (MSCs) derived from bone marrow or hyaline cartilage, there is little to no data about the presence of MSCs in the joint capsule or the ligamentum capitis femoris (LCF) of the hip joint.
13p
vimariana2711
22-12-2020
12
0
Download
-
Sonic hedgehog (Shh) is an important signalling protein involved in the induction of early cartilaginous differentiation. Herein, we demonstrate that Shh markedly induces chondrogenesis of rabbit bone marrow stromal cells (BMSCs) under microgravity conditions, and promotes cartilage regeneration.
12p
viwyoming2711
16-12-2020
13
0
Download
-
The osteogenic capability of the scaffold is influenced by the interconnections between the scaffold pores which facilitate cell distribution, integration with the host tissue and capillary ingrowth. Hence, the preparation of bone scaffolds with applicable pore size and interconnectivity is a significant issue in bone tissue engineering
9p
tamynhan4
06-09-2020
13
2
Download
-
Tissue engineering and bone substitutes are subjects of intensive ongoing research. If the healing of bone fractures is delayed, osteoinductive materials that induce mesenchymal stem cells (MSCs) to form bone are necessary.
9p
viuchiha2711
21-04-2020
12
0
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)