![](images/graphics/blank.gif)
Breast cancer model
-
Circulating tumor cell (CTC) clusters play a critical role in carcinoma metastasis. However, the rarity of CTC clusters and the limitations of capture techniques have retarded the research progress. In vitro CTC clusters model can help to further understand the biological properties of CTC clusters and their clinical significance.
17p
vishanshan
27-06-2024
1
1
Download
-
This research aimed to create a robust signature with hypoxia-related genes to predict the prognosis of breast cancer patients. The function of hypoxia genes was further studied through cell line experiments.
12p
vishanshan
27-06-2024
3
1
Download
-
This research designeded to: 1. Analyze the efficacy and safety of Palbociclib treatment in HR-positive and HER2-negative (HR+/HER2-) metastatic breast cancer(MBC) patients. 2. Establish and validate a nomogram model for predicting the progression-free survival (PFS) rates of 6 months, 12 months, and 18 months in HR+/HER2- MBC patients after receiving Palbociclib plus endocrine therapy (ET).
13p
vishanshan
27-06-2024
2
1
Download
-
Gastric cancer is one of the most common tumors worldwide, and most patients are deprived of treatment options when diagnosed at advanced stages. PRDM14 has carcinogenic potential in breast and non-small cell lung cancer. however, its role in gastric cancer has not been elucidated.
13p
vikoch
27-06-2024
1
1
Download
-
Since the Z0011 trial, the assessment of axillary lymph node status has been redirected from the previous assessment of the occurrence of lymph node metastasis alone to the assessment of the degree of lymph node loading. Our aim was to apply preoperative breast ultrasound and clinicopathological features to predict the diagnostic value of axillary lymph node load in early invasive breast cancer.
10p
vikoch
27-06-2024
1
1
Download
-
Knowing the activity of the mutational processes shaping a cancer genome may provide insight into tumorigenesis and personalized therapy. It is thus important to characterize the signatures of active mutational processes in patients from their patterns of single base substitutions.
12p
vibransone
28-03-2024
9
2
Download
-
Estrogen receptor (ER) activity is critical for the development and progression of the majority of breast cancers. It is known that ER is differentially bound to DNA leading to transcriptomic and phenotypic changes in different breast cancer models.
11p
vioraclene
31-03-2024
5
2
Download
-
More accurate diagnostic methods are pressingly needed to diagnose breast cancer, the most common malignant cancer in women worldwide. Blood-based metabolomics is a promising diagnostic method for breast cancer. However, many metabolic biomarkers are difficult to replicate among studies.
14p
vioraclene
31-03-2024
3
2
Download
-
Contemporary deep learning approaches show cutting-edge performance in a variety of complex prediction tasks. Nonetheless, the application of deep learning in healthcare remains limited since deep learning methods are often considered as non-interpretable black-box models.
16p
vibransone
28-03-2024
4
2
Download
-
Preclinical studies and early clinical trials have shown that targeting cancer neoantigens is a promising approach towards the development of personalized cancer immunotherapies. DNA vaccines can be rapidly and efficiently manufactured and can integrate multiple neoantigens simultaneously.
13p
vibransone
28-03-2024
7
2
Download
-
Circulating tumor DNA (ctDNA) offers minimally invasive means to repeatedly interrogate tumor genomes, providing opportunities to monitor clonal dynamics induced by metastasis and therapeutic selective pressures. In metastatic cancers, ctDNA profiling allows for simultaneous analysis of both local and distant sites of recurrence. Despite the promise of ctDNA sampling, its utility in real-time genetic monitoring remains largely unexplored.
17p
vibransone
28-03-2024
3
2
Download
-
Ebook "Computational biology: Issues and applications in oncology" provides a comprehensive report on recent techniques and results in computational oncology essential to the knowledge of scientists, engineers, as well as postgraduate students working on the areas of computational biology, bioinformatics, and medical informatics. With chapters timely prepared and written by experts in the field, this in-depth and up-to-date volume covers advanced statistical methods, heuristic algorithms, cluster analysis, data modeling, image and pattern analysis applied to cancer research.
309p
cotieubac1004
15-03-2024
4
0
Download
-
There has been a growing appreciation recently that mutagenic processes can be studied through the lenses of mutational signatures, which represent characteristic mutation patterns attributed to individual mutagens.
15p
vicwell
29-02-2024
7
1
Download
-
Evolutionary models of breast cancer progression differ on the extent to which metastatic potential is pre-encoded within primary tumors. Although metastatic recurrences often harbor putative driver mutations that are not detected in their antecedent primary tumor using standard sequencing technologies, whether these mutations were acquired before or after dissemination remains unclear.
19p
vicwell
29-02-2024
4
2
Download
-
Part 1 book "Biomedical tissue culture" includes content: Culture conditions and types of growth media for mammalian cells, cell handling and culture under controlled oxygen concentration, contamination of tissue cultures by mycoplasmas, isolation of breast cancer stem cells by single cell sorting, in vitro, tissue based models as a replacement for animal models in testing of drugs at the preclinical stages, use of cell culture to prove syncytial connection and fusion of neurons.
123p
muasambanhan07
20-02-2024
3
0
Download
-
Ebook "Mammary gland development: Methods and protocols" provides key molecular biological protocols and experimental strategies currently employed to study the various stages of mammary gland development. Chapters are divided into four parts covering genetically modified mouse models that exhibit prenatal and pubertal mammary gland phenotypes, 2D and 3D-model culture systems, methodologies for mammary stem cell isolation, and translational applications that provide a bridge between experimental studies of mammary gland development and the study of human breast cancer.
357p
lucchinguyen
28-12-2023
7
3
Download
-
Part 2 book "Mouse as a model organism" includes content: Experimental tumour models in mice; exploration of mmp function in mouse models of angiogenesis; tumor stroma interactions - focus on fibroblasts; experimental procedures to assay invasion associated activities of primary cultured fibroblasts; systemic instigation - a mouse model to study breast cancer as a systemic disease.
77p
muasambanhan03
25-12-2023
5
1
Download
-
MicroRNAs (miRNAs) play pivotal roles in the development and progression of breast cancer (BC). In this study, we attempted to identify miRNAs associated with BC prognosis and progression via integrated analysis.
13p
vileonardodavinci
23-12-2023
8
2
Download
-
Since the publication of MA-20 and EORTC-22922 trials, chest wall (CW)/ whole breast (WB) irradia‑ tion+comprehensive regional nodal irradiation (RNI) with internal mammary node irradiation (IMNI) has been the standard adjuvant treatment for early-stage breast cancer (BC).
8p
vileonardodavinci
23-12-2023
5
2
Download
-
The objective of this paper is to explore the value of a delta-radiomic model of the axillary lymph node (ALN) using dynamic contrast-enhanced (DCE) MRI for early prediction of the axillary pathological complete response (pCR) of breast cancer patients after neoadjuvant chemotherapy (NAC).
13p
vileonardodavinci
23-12-2023
8
3
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)