Breast carcinoma MCF7

Xem 1-2 trên 2 kết quả Breast carcinoma MCF7

Screening of the small molecule library of Meinox enables the identification of anticancer compounds in pathologically distinct cancers

Meinox’s small molecule library was also tested in vitro for pathologically distinct forms of cancer, including pancreatic adenocarcinoma PANC1, breast carcinoma MCF7, and lymphoblastic carcinoma RS4-11 cell lines. Analysis of this library at a dose of 1 μM allowed the discovery of potent, specific or broadly active anticancer compounds against pathologically distinct cancers. This study shows that in vitro analysis of different cancers or other phenotypic assays with Meinox small molecule library may generate novel and potent bioassay-specific compounds.

13p thiencuuchu 27-11-2021 19 1 Download

Cytotoxic steroids from the mushroom Ganoderma australe collected in Laos

Their structures were characterized by the combination of HR-MS, one and two dimensional NMR spectroscopic analyses. In addition, ergosterol peroxide and kansenone showed good cytotoxicity against four cancer cell lines, KB (human epidermal carcinoma), MCF7 (human breast carcinoma), SK-LU-1 (human lung carcinoma) and Hep-G2 (hepatocellular carcinoma). This is the first report on the chemical constituents and cytotoxic steroids from Ganoderma sp. in Laos.

5p lamtan3547 04-11-2018 20 1 Download