Cancer chemotherapy

This research project aims to: Investigate the safety, the feasibility and the effect of the laparoscopic debulking surgery in the treatment of advanced ovarian cancer (IIIC-IV stages) after neoadjuvant chemotherapy; Analysis of general characteristics, outcomes of postoperative survival time in total number of patients studied.

6p vinatisu 29-08-2024 1 1   Download

Appendiceal cancer is a very rare disease. Based on 6 cases of appendiceal cancer who were admitted to the Internal Medicine of Breast, Gastroenterology, Hepatology, Urology, Department, Oncology Hospital of Ho Chi Minh City from September 2019 to March 2021, we evaluate the available literature review about diagnosis and treatment of appendiceal cancer.

4p vinatisu 29-08-2024 2 0   Download

Assess clinical, subclinical characteristics of stage IB-IIIA non - small cell lung cancer patients (NSCLC). Evaluating the result of adjuvant vinorelbine plus cisplatin in completely resected stage IB - IIIA NSCLC.

6p vinatisu 29-08-2024 2 0   Download

Hue Central Hospital is a special-grade central - level hospital that has been and is promoting comprehensive patient care. The teamwork between treating physicians, nursing care, clinical pharmacists and nutritionists has initially shown positive patient treatment outcomes.

7p vinatisu 29-08-2024 1 0   Download

The metronomic concept emerged more than 20 year sago, however, a significant development in various solidtumors was noticed in the past 10 years. There are potentially several mechanisms of action against tumor cells including inhibition of angiogenesis. This study aims to assess the efficacy and the safety of ametronomic schedule of oral Vinorelbine (Navelbine) in treatment of metastatic breast cancer.

6p vinatisu 29-08-2024 1 0   Download

Acute leukemia is the most commont cancer in children and is curable if correctly diagnosed and effectively treated. The diagnosis and accurate cloning of acute leukemia play an important role in the treatment results for regimens and prognosis between two myeloid and lymphoid completely different.

5p vinatisu 29-08-2024 4 1   Download

The global rise in aging population led to the increase of the number of elderly patients with lung cancer. Due to the impairment of the function of multiple organs, the work-up and treatment NSCLC for older patients become more difficult than adults.

5p vinatisu 29-08-2024 5 1   Download

We conducted the study to describe the alopecia characteristics of patients treated with chemotherapy, and to identify the distress level of cancer patients using CADS and the preference of patients to deal with the CIA.

7p vinatisu 29-08-2024 3 1   Download

Brain metastasis is common in patients with non-small cell lung cancer (NSCLC) and it is associated with poorer prognosis. Several options to control the secondary brain tumors in the context include chemotherapy, whole-brain radiation, stereotactic surgery, surgery. However, chemotherapy is ineffective to those patients because of poor penetration through the blood-brain barrier. Whole-brain radiation therapy used to be a standard option for brain metastases.

5p vinatisu 29-08-2024 4 1   Download

RNA cargo in exosomes, especially microRNAs (miRNAs), play an important role in the chemotherapy drug resistance of human cancers. However, the role and mechanism of exosomal miR-107 on multidrug resistance of gastric cancer cells was still not clear. In this study, we sought to explore whether exosomal miR-107 could reverse the resistance of gastric cancer cells to the chemotherapy drugs.

16p vielonmusk 21-01-2022 13 0   Download

Pegylated liposomal doxorubicin (PLD) is an improved formulation of doxorubicin with comparable effectiveness but significantly lower cardiotoxicity than conventional anthracycline. This study aimed to evaluate the real-world effectiveness and safety of PLD versus epirubicin as neoadjuvant or adjuvant treatment for breast cancer.

11p vielonmusk 21-01-2022 13 1   Download

To examine the prevalence and prognostic role of tumor microenvironment (TME) markers in uterine carcinosarcoma (UCS) through immunohistochemical characterization. Methods: The internal database of our institution was queried out for women with UCS who underwent surgery and thereafter postoperative chemotherapy with carboplatin and paclitaxel between January 2012 and December 2017.

11p vielonmusk 21-01-2022 12 1   Download

Extensive-stage small cell lung cancer (ES-SCLC) is an aggressive disease with poor survival, and platinum-etoposide chemotherapy is indicated as the mainstay of treatment. In this study, we compared the efficacy and safety between the cisplatin plus etoposide (EP) and carboplatin plus etoposide (EC) regimens.

7p vielonmusk 21-01-2022 14 1   Download

The prognosis of pancreatic cancer (PC) has been improved by new chemotherapy regimens (combination of 5-fuorouracil, oxaliplatin, irinotecan, and leucovorin (FOLFIRINOX) or gemcitabine plus nab-paclitaxel (GnP)). Unfortunately, chemotherapy-induced peripheral neuropathy (CIPN) is a common adverse event of these two regimens. The efficacy of pregabalin for CIPN has been reported in previous studies.

7p vielonmusk 21-01-2022 13 1   Download

To evaluate the prognostic value of the apparent diffusion coefficient (ADC) derived from difusionweighted magnetic resonance imaging (MRI) and monitor the early treatment response to induction chemotherapy (IC) with plasma EBV DNA in locoregionally advanced nasopharyngeal carcinoma (LA-NPC).

9p vielonmusk 21-01-2022 12 1   Download

To investigate the difference between doublet and triplet neoadjuvant chemotherapy (NAC) regimens in efficacy and safety profile. Methods: A total of 227 locally advanced gastric cancer (LAGC) patients who received NAC and sequential radical gastrectomy were reviewed. After propensity score matching (PSM), 140 patients with similar baseline characteristics were selected.

11p vielonmusk 21-01-2022 10 2   Download

The optimal treatment of stage IV rectal cancer remains controversial. The purpose of this study was to assess the treatment outcomes and toxicity of neoadjuvant chemotherapy and radiotherapy followed by local treatment of all tumor sites and subsequent adjuvant chemotherapy in stage IV rectal cancer patients with potentially resectable metastases.

10p vielonmusk 21-01-2022 13 1   Download

Cancer-related fatigue (CRF) is one of the most common and distressing complaints reported by cancer patients during chemotherapy considerably impacting all aspects of a patient’s life (physical, psychosocial, professional, and socioeconomic).

11p vielonmusk 21-01-2022 13 1   Download

Human papillomavirus (HPV)-associated oropharyngeal cancer (OPC) has a favorable prognosis which has led to efforts to de-intensify treatment. Response-adaptive de-escalated treatment is promising, however improved biomarkers are needed. Quantitative cell-free HPV-DNA (cfHPV-DNA) in plasma represents an attractive non-invasive biomarker for grading treatment response and post-treatment surveillance.

8p vielonmusk 21-01-2022 12 0   Download

Eribulin methylate (eribulin) improved the overall survival (OS) of eribulin-treated patients with HER2- negative advanced breast cancer (ABC) in prospective and retrospective studies. However, the effect of eribulin on OS as first-line chemotherapy and the characteristics of the patients who benefited from eribulin remain unclear.

10p vielonmusk 21-01-2022 16 1   Download