Cancer immunology

PD-L1 showed abnormal mRNA and protein expression in a variety of cancers and predicted prognosis in cancer patients. Furthermore, across a variety of cancer types, the aberrant PD-L1 expression was connected to the MSI, MMR, TMB, drug sensitivity, and tumor immune microenvironment (TIME). Moreover, PD-L1 was significantly correlated with infiltrating levels of immune cells (T cell CD8+, neutrophil, and so on).

19p vishanshan 27-06-2024 1 1   Download

NUP155 is reported to be correlated with tumor development. However, the role of NUP155 in tumor physiology and the tumor immune microenvironment (TIME) has not been previously examined. This study comprehensively investigated the expression, immunological function, and prognostic significance of NUP155 in different cancer types.

22p vikoch 27-06-2024 3 1   Download

Currently, over half of breast cancer cases are unrelated to known risk factors, highlighting the importance of discovering other cancer-promoting factors. Since crosstalk between gut microbes and host immunity contributes to many diseases, we hypothesized that similar interactions could occur between the recently described breast microbiome and local immune responses to influence breast cancer pathogenesis.

17p vibransone 28-03-2024 3 1   Download

Single-cell transcriptomics (scRNA-seq) has become essential for biomedical research over the past decade, particularly in developmental biology, cancer, immunology, and neuroscience. Most commercially available scRNA-seq pro‑ tocols require cells to be recovered intact and viable from tissue.

18p viellison 28-03-2024 4 1   Download

Continued part 1, part 2 of ebook BioChemistry (8th edition) provides readers with contents including: Nucleic acid biotechnology techniques; Viruses, cancer, and immunology; The importance of energy changes and electron transfer in metabolism; Carbohydrates; Glycolysis; Storage mechanisms and control in carbohydrate metabolism; The citric acid cycle; Electron transport and oxidative phosphorylation;...

451p coduathanh1122 27-03-2024 7 1   Download

Part 3 book "Wong’s essentials of pediatric nursing" includes content: The child with problems related to the production and circulation of blood, the child with a disturbance of regulatory mechanisms, the child with a problem that interferes with physical mobility.

753p muasambanhan08 04-03-2024 5 1   Download

The crosstalk between cancer and the tumour immune microenvironment (TIME) has attracted significant interest in the latest years because of its impact on cancer evolution and response to treatment. Despite this, cancer-specific tumour-TIME interactions and their mechanistic insights are still poorly understood.

17p vicwell 29-02-2024 3 1   Download

T-cells play a crucial role in the adaptive immune system by triggering responses against cancer cells and pathogens, while maintaining tolerance against self-antigens, which has sparked interest in the development of various T-cell-focused immunotherapies.

24p vicwell 29-02-2024 2 1   Download

Cancer immunotherapies including immune checkpoint inhibitors and Chimeric Antigen Receptor (CAR) T-cell therapy have shown variable response rates in paediatric patients highlighting the need to establish robust biomarkers for patient selection.

24p vicwell 29-02-2024 1 1   Download

Part 1 book "Cancer immunology and immunotherapy" includes content: Immune infiltration in human cancer - prognostic significance and disease control, subversion and coercion - the art of redirecting tumor immune surveillance, a target to enhance antitumor immune response, biology and clinical observations of regulatory T-cells in cancer immunology, concepts and ways to amplify the antitumor immune response, angiogenesis and the tumor vasculature as antitumor immune modulators - The role of vascular endothelial growth factor and endothelin.

163p muasambanhan08 23-02-2024 6 1   Download

Part 2 book "Cancer immunology and immunotherapy" includes content: Adoptive cellular therapy, dendritic cell subsets as vectors and targets for improved cancer therapy, identification of human idiotype specific T-cells in lymphoma and myeloma, immunologically active biomaterials for cancer therapy,... and other contents.

156p muasambanhan08 23-02-2024 10 1   Download

Ebook Concise oral medicine: Part 2 includes content: Temporomandibular joint disorders, temporomandibular joint disorders, oral cancer and precancerous lesions, immunological diseases, forensic odontology, orofacial syndromes, differential diagnosis of miscellaneous diseases,… and other contents.

126p longtimenosee03 01-02-2024 5 0   Download

Immune checkpoint inhibitors have revolutionized therapy of advanced and metastatic cancers. However, a significant proportion of patients do not respond to immune checkpoint inhibitors or develop resist‑ ance. Therefore, novel therapies or combinations of therapies that may act synergistically are needed.

7p vitiki 30-01-2024 5 2   Download

Part 3 book "Veterinary immunology" includes content: Organ graft rejection and pregnancy; cancer immunology and immunotherapy; autoimmunity; organ specific autoimmune diseases; immune mediated inflammatory diseases; primary immunodeficiencies; secondary immunological defects; drugs and other agents that affect the immune system; immunodiagnostic techniques; evolution of the immune system.

625p muasambanhan03 02-01-2024 3 2   Download

Anaplastic thyroid carcinoma (ATC) was a rare malignancy featured with the weak immunotherapeutic response. So far, disorders of immunogenic cell death genes (ICDGs) were identified as the driving factors in cancer progression, while their roles in ATC remained poorly clear.

14p vileonardodavinci 23-12-2023 4 2   Download

Hexokinase 2 (HK2) is an enzyme that catalyses the conversion of glucose to glucose-6-phosphate, which has been found to be associated with malignant tumour growth. However, the potential immunological and clinical significance of HK2, especially in terms of prognostic prediction for patients with glioma, has not been fully elucidated.

20p vialfrednobel 23-12-2023 6 3   Download

Tumor necrosis factor alpha-induced protein 2 (TNFAIP2), a TNFα-inducible gene, appears to participate in inflammation, immune response, hematopoiesis, and carcinogenesis. However, the potential role of TNFAIP2 in the development of acute myeloid leukemia (AML) remains unknow yet. Therefore, we aimed to study the biological role of TNFAIP2 in leukemogenesis.

16p vialfrednobel 23-12-2023 6 3   Download

Thyroid cancer (THCA) has become increasingly common in recent decades, and women are three to four times more likely to develop it than men. Evidence shows that estrogen has a significant impact on THCA proliferation and growth. Nevertheless, the effects of estrogen-related genes (ERGs) on THCA stages, immunological infiltration, and treatment susceptibility have not been well explored.

20p vialfrednobel 23-12-2023 3 2   Download

Part 2 book "Immunology" includes content: Immunity to protozoa and worms; primary immunodeficiencies; aids, secondary immunodeficiency and immunosuppression; vaccination; immunological tolerance; autoimmunity and autoimmune disease; transplantation and rejection; immunity to cancers; immediate hypersensitivity; hypersensitivity; hypersensitivity; hypersensitivity.

289p oursky08 04-11-2023 1 1   Download

The immunological checkpoint known as Inducible T Cell Costimulatory Factor (ICOS, Cluster of Differentiation, CD278) is activated and expressed on T cells. Both somatic cells and antigen-presenting cells expressed its ligand, ICOSL (including tumor cells in the tumor microenvironment). It is important for immunosuppression. Uncertainty surrounds the function of ICOS in tumor immunity.

15p vischultz 20-10-2023 3 2   Download