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Carbapenem resistant Enterobacteriaceae
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Carbapenem-resistant Enterobacteriaceae are considered by WHO as “critical” priority pathogens for which novel antibiotics are urgently needed. The dissemination of carbapenemase-producing Escherichia coli (CP-Ec) in the community is a major public health concern. However, the global molecular epidemiology of CP-Ec isolates remains largely unknown as well as factors contributing to the acquisition of carbapenemase genes.
18p
vibransone
28-03-2024
4
2
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Enterobacteriaceae are the most frequently isolated organisms from clinical specimens. Among them Escherichia coli and Klebsiella pneumoniae cause a wide variety of clinical infections. With the emergence of ESBLs, carbapenems became the drug of choice. During the past decade, there has been an emergence of carbapenems-resistant Enterobacteriaceae that produce carbapenamases.
6p
caygaocaolon11
21-04-2021
11
1
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Sự gia tăng của trực khuẩn Gram âm đường ruột kháng Carbapenem (Carbapenem resistant Enterobacteriaceae - CRE) đang ở mức báo động về tỷ lệ lưu hành trên thế giới. Bài viết trình bày xác định tỷ lệ người bệnh bị chiếm cư CRE tại thời điểm nhập Khoa ICU và các yếu tố liên quan tại Bệnh viện Đại học Y Dược Thành phố Hồ Chí Minh (BVĐHYD TPHCM).
6p
vihampshire2711
14-03-2021
24
2
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Carbapenems are one of the β-Lactam antibiotics with a broad spectrum of antibacterial activity. Inappropriate use of this antibiotic can produce resistance strains by production of carbapenemases enzyme. The Klebsiella pneumoniae carbapenemase (KPC) is the most important mechanism of enzymatic resistance seen in Enterobacteriaceae isolated especially Klebsiella pneumoniae. The aim and objectives of this study was isolation and detection of the Carbapenem resistant Klebsiella species strains with phenotypic methods. Out of 11248 samples, 602 Klebsiella species (33.
6p
nguaconbaynhay8
13-10-2020
11
1
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Enterobacteriaceae are inhabitants of the intestinal flora. Emergence of Carbapenem resistant Enterobacteriaceae (CRE) is a serious threat to public health. They rapidly acquire and transfer drug resistance genes through plasmids and transposons and spread to community via faeco-oral route. Hence the present study was done to know the magnitude of Carbapenem resistant Enterobacteriaceae in our hospital. This study was conducted in the department of Microbiology, SIMS and RH, Tumkuru during a period from May 2016 to October 2016.
6p
kethamoi6
29-06-2020
17
2
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Carbapenamse Resistant Enterobacteriaceae (CRE) have disseminated widely since being first reported in 2001. CRE often carry genes that confer high levels of resistance to many other antimicrobials. So they are usually resistant to all β-lactam agents as well as most other classes of antimicrobial agents.
10p
nguaconbaynhay6
24-06-2020
12
0
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Gram negative enteric bacilli are a leading cause for sepsis in children and adults. The infections caused by Enterobacteriaceae are community and hospital-acquired. These bacteria have the potential to spread in the hospital environment and also across continents. Current study was designed to characterise Escherichia coli isolates from blood stream infection and identify the genes responsible for carbapenemase production and correlate the results with MHT.
6p
angicungduoc4
04-05-2020
19
1
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The worldwide spread of carbapenem-resistant Enterobacteriaceae (CRE) has become a major challenge in healthcare settings. This study aimed to screen the susceptibility to imipenem and meropenem, among 49 Klebsiella and 7 Proteus vulgaris clinical isolates from Egypt. The combinations of carbapenems with ciprofloxacin, rifampicin, amikacin and colistin were tested against CRE. Attempts to cure plasmids mediating carbapenem resistance using menthol, as a natural curing agent, as well as to test its efficacy when combined with other antibiotics against CRE, were done.
17p
nguathienthan4
18-04-2020
14
2
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Critical care populations are at high risk for Multi drug resistant organisms (MDRO) colonization because of rampant use of broad-spectrum antibiotics leading to colonization with resistant strains, Screening for MDR organisms is one of the many approaches needed to deal with the very major clinical problem concerning drug resistance.
9p
caygaocaolon4
01-04-2020
18
1
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Antibiotic resistance is observed in both pathogenic and normal commensal flora. Gastrointestinal tract may serve as a reservoir for carbapenem resistant Enterobacteriaceae (CRE), resulting in cross transmission within / among health care settings. Awareness of the fecal carriage of Extended spectrum Beta lactamase (ESBL) and CarbapenemaseProducing Enterobacteriaceae (CPE) bacteria is very important for the clinicians, microbiologists, infection control practitioners and epidemiologists.
7p
chauchaungayxua3
07-02-2020
18
0
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The drug resistance among the gram negative bacteria is present as a serious global problem. ESBLs and MBLs are the important members of beta-lactamases produced mainly by gram negative bacteria and are responsible for mediating resistance to extendedspectrum cephalosporins and carbapenem. These enzymes are commonly detected in the members of the Enterobacteriaceae like Klebsiella pneumoniae and Escherichia coli. A cross-sectional study was conducted at Department of Microbiology, Santosh Medical College & Hospital Ghaziabad by using K. pneumoniae isolated from sputum samples.
7p
chauchaungayxua3
07-02-2020
17
0
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MBL producing members of family Enterobacteriaceae have been responsible for numerous outbreaks of infection throughout the world. A total of 108 non repetitive carbapenem resistant strains isolated from various clinical samples, identified by standard microbiological techniques and antimicrobial susceptibility pattern was determined. MBL detection was done by combined disc test using ceftazidime-EDTA, imipenemEDTA and meropenem-EDTA. Ceftazidime-EDTA detected 90 (97.8%) isolates, imipenem-EDTA detected 14 (15.2%) isolates and meropenemEDTA detected 13 (14.
5p
nguaconbaynhay3
07-02-2020
24
1
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A review of -multidrug-resistant Enterobacteriaceae in a neonatal unit in Johannesburg, South Africa
Multi-drug resistant organisms are an increasingly important cause of neonatal sepsis. Aim: This study aimed to review neonatal sepsis caused by multi-drug resistant Enterobacteriaceae (MDRE) in neonates in Johannesburg, South Africa.
9p
virome2711
13-01-2020
11
1
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K. pneumoniae is responsible for a wide variety of hospital and community-acquired infections, affecting patients with normal immune systems as well as those with pre-existing conditions. The Carbapenems are β-lactam antibiotics that are used in the treatment of infections caused by Extended Spectrum beta-Lactamases (ESBL) producing gram negative bacteria (GNB). Carbapenem antibiotics are considered the drugs of choice for the treatment of ESBL -producing Enterobacteriaceae and other multidrug resistant bacteria.
11p
quenchua2
18-12-2019
10
0
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Carbapenemase producing carbapenem resistant Enterobacteriacea were almost non-existent till 1990s but nowadays they are routinely encountered in hospitals. KPC producing Klebsiella pneumoniae were the first to develop and occur commonly. Lately NDM producing Enterobacteriaceae have emerged. IMP and VIM genes in Carbapenem resistant Enterobacteriaecae have started to emerge but the prevalence is low.
7p
quenchua2
15-12-2019
8
0
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